Brewster, R; Bi, W L; Smith, T R; Gormley, W B; Dunn, I F; Laws Jr., E R
The neurosurgeon as baseball fan and inventor: Walter Dandy and the batter's helmet Journal Article
In: Neurosurgical Focus, vol. 39, no. 1, 2015.
Abstract | Links | BibTeX | Tags: 19th Century, 20th Century, Baseball, Baseball helmet, brain concussion, Head Protective Devices, Head trauma, Helmet, HISTORY, human, Humans, Injuries, Innovation, Male, middle aged, neurosurgeon, Neurosurgeons, Protective gear, traumatic brain injury, Walter dandy
@article{Brewster2015,
title = {The neurosurgeon as baseball fan and inventor: Walter Dandy and the batter's helmet},
author = {Brewster, R and Bi, W L and Smith, T R and Gormley, W B and Dunn, I F and {Laws Jr.}, E R},
doi = {10.3171/2015.3.FOCUS1552},
year = {2015},
date = {2015-01-01},
journal = {Neurosurgical Focus},
volume = {39},
number = {1},
abstract = {Baseball maintains one of the highest impact injury rates in all athletics. A principal causative factor is the "beanball," referring to a pitch thrown directly at a batter's head. Frequent morbidities elicited demand for the development of protective gear development in the 20th century. In this setting, Dr. Walter Dandy was commissioned to design a "protective cap" in 1941. His invention became widely adopted by professional baseball and inspired subsequent generations of batting helmets. As a baseball aficionado since his youth, Walter Dandy identified a natural partnership between baseball and medical practice for the reduction of beaning-related brain injuries. This history further supports the unique position of neurosurgeons to leverage clinical insights, inform innovation, and expand service to society. © AANS, 2015.},
keywords = {19th Century, 20th Century, Baseball, Baseball helmet, brain concussion, Head Protective Devices, Head trauma, Helmet, HISTORY, human, Humans, Injuries, Innovation, Male, middle aged, neurosurgeon, Neurosurgeons, Protective gear, traumatic brain injury, Walter dandy},
pubstate = {published},
tppubtype = {article}
}
Lawrence, D W; Comper, P; Hutchison, M G; Sharma, B
The role of apolipoprotein E episilon ($epsilon$)-4 allele on outcome following traumatic brain injury: A systematic review Journal Article
In: Brain Injury, vol. 29, no. 9, pp. 1018–1031, 2015.
Abstract | Links | BibTeX | Tags: 80 and over, aged, allele, Alleles, Alzheimer disease, amyloid beta protein, APOE, apolipoprotein E, apolipoprotein E4, Article, athlete, brain concussion, Brain Injuries, clinical evaluation, cognition, cognitive defect, disease severity, Female, follow up, genetic association, genetic risk, genetics, GENOTYPE, Glasgow Outcome Scale, heterozygote, histopathology, homozygote, human, Humans, Incidence, injury severity, Male, Memory, nerve cell necrosis, neuropathology, Neuroprotection, outcome assessment, pediatrics, Prevalence, Prognosis, prognostic assessment, protein function, psychologic test, psychology, Recovery, scoring system, Systematic Review, tau protein, traumatic brain injury, treatment outcome, very elderly, Wechsler Intelligence Scale
@article{Lawrence2015,
title = {The role of apolipoprotein E episilon ($epsilon$)-4 allele on outcome following traumatic brain injury: A systematic review},
author = {Lawrence, D W and Comper, P and Hutchison, M G and Sharma, B},
doi = {10.3109/02699052.2015.1005131},
year = {2015},
date = {2015-01-01},
journal = {Brain Injury},
volume = {29},
number = {9},
pages = {1018--1031},
abstract = {Background: The apolipoprotein E gene (APOE) has emerged as a candidate for prognosticating traumatic brain injury (TBI) recovery, with APOE$epsilon$4 identified as a susceptibility marker for poor outcome, despite large discrepancy in its reported influence post-TBI.Methods: A systematic review was conducted, including all primary articles investigating the role of APOE$epsilon$4 on TBI outcome. A total of 65 studies were included, including 24 predominantly investigating mild (mTBI), seven moderate (modTBI) and 33 severe (sTBI); severity was not reported in one study.Results: In mTBI studies, the association between APOE$epsilon$4 and post-TBI outcome was concluded as non-contributory in 14 studies (58.3%), hazardous in nine (37.5%) and protective in one (4.2%). In sTBI studies, the role of APOE$epsilon$4 was hazardous in 21 (63.6%), non-contributory in nine (27.3%) and protective in three (9.1%). Of the seven studies investigating dementia outcomes, four observed a hazardous association with APOE$epsilon$4, while three reported no association. Six studies examined Alzheimers dementia pathology, of which three reported a hazardous influence of APOE$epsilon$4.Conclusions: The influence of APOE$epsilon$4 on neuropsychological testing, functional outcome and in paediatric populations was incongruous. This review supports the majority of research indicating APOE$epsilon$4 adversely influences recovery following TBI, particularly with respect to dementia-related outcomes and outcomes following sTBI. © 2015 Taylor \& Francis Group, LLC.},
keywords = {80 and over, aged, allele, Alleles, Alzheimer disease, amyloid beta protein, APOE, apolipoprotein E, apolipoprotein E4, Article, athlete, brain concussion, Brain Injuries, clinical evaluation, cognition, cognitive defect, disease severity, Female, follow up, genetic association, genetic risk, genetics, GENOTYPE, Glasgow Outcome Scale, heterozygote, histopathology, homozygote, human, Humans, Incidence, injury severity, Male, Memory, nerve cell necrosis, neuropathology, Neuroprotection, outcome assessment, pediatrics, Prevalence, Prognosis, prognostic assessment, protein function, psychologic test, psychology, Recovery, scoring system, Systematic Review, tau protein, traumatic brain injury, treatment outcome, very elderly, Wechsler Intelligence Scale},
pubstate = {published},
tppubtype = {article}
}
Bowman, T G; Breedlove, K M; Breedlove, E L; Dodge, T M; Nauman, E A
Impact attenuation properties of new and used lacrosse helmets Journal Article
In: Journal of Biomechanics, vol. 48, no. 14, pp. 3782–3787, 2015.
Abstract | Links | BibTeX | Tags: Accident prevention, Article, Athletic Injuries, attenuation, brain concussion, Cracks, Drop test, Drops, Equipment Design, Gadd Severity Index, head impact, Head Protective Devices, Helmet, Helmet evaluation, human, Humans, Injuries, lacrosse helmet, Materials testing, mechanical stress, priority journal, protective equipment, racquet sport, Racquet Sports, recertification, rigidity, Safety devices, Severity index, Sporting goods, Sports Equipment, standards, stress strain relationship, velocity
@article{Bowman2015,
title = {Impact attenuation properties of new and used lacrosse helmets},
author = {Bowman, T G and Breedlove, K M and Breedlove, E L and Dodge, T M and Nauman, E A},
doi = {10.1016/j.jbiomech.2015.08.026},
year = {2015},
date = {2015-01-01},
journal = {Journal of Biomechanics},
volume = {48},
number = {14},
pages = {3782--3787},
abstract = {The National Operating Committee on Standards for Athletic Equipment (NOCSAE) has developed impact attenuation thresholds that protective helmets worn in sport must meet to be commercially available in an attempt to prevent injury. It remains unknown how normal helmet use in athletic activity alters the force attenuation ability of lacrosse helmets. We tested 3 new and 3 randomly selected used helmets from 2 popular lacrosse models (Cascade Pro7, Cascade CPXR). All used helmets had been worn for 3 collegiate seasons prior to testing and had never been refurbished. Helmets were drop-tested using 3 prescribed impact velocities at 6 locations according to the NOCSAE lacrosse helmet standard, and we compared the Gadd Severity Index (GSI) scores between new and used helmets using a repeated measure ANOVA with location as the repeated variable and data separated by impact velocity. All 12 helmets passed the NOCSAE GSI threshold for all testing conditions; however 1 used helmet shell cracked resulting in a failed test. We found a significant main effect for helmet age at the low (F5},
keywords = {Accident prevention, Article, Athletic Injuries, attenuation, brain concussion, Cracks, Drop test, Drops, Equipment Design, Gadd Severity Index, head impact, Head Protective Devices, Helmet, Helmet evaluation, human, Humans, Injuries, lacrosse helmet, Materials testing, mechanical stress, priority journal, protective equipment, racquet sport, Racquet Sports, recertification, rigidity, Safety devices, Severity index, Sporting goods, Sports Equipment, standards, stress strain relationship, velocity},
pubstate = {published},
tppubtype = {article}
}
De Matteo, C; Volterman, K A; Breithaupt, P G; Claridge, E A; Adamich, J; Timmons, B W
Exertion testing in youth with mild traumatic brain injury/concussion Journal Article
In: Medicine & Science in Sports & Exercise, vol. 47, no. 11, pp. 2283–2290, 2015.
Abstract | Links | BibTeX | Tags: Adolescent, adolescents, brain concussion, Child, children, Cross-Sectional Studies, cross-sectional study, exercise, exercise test, exercise tolerance, Female, head injury, human, Humans, Male, Pathophysiology, Physical Exertion, Post-Concussion Syndrome, postconcussion syndrome, Return to Play, return to sport, time factor, Time Factors
@article{DeMatteo2015,
title = {Exertion testing in youth with mild traumatic brain injury/concussion},
author = {{De Matteo}, C and Volterman, K A and Breithaupt, P G and Claridge, E A and Adamich, J and Timmons, B W},
doi = {10.1249/MSS.0000000000000682},
year = {2015},
date = {2015-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {47},
number = {11},
pages = {2283--2290},
abstract = {Purpose The decision regarding return to activity (RTA) after mild traumatic brain injuries/concussion is one of the most difficult and controversial areas in concussion management, particularly for youth. This study investigated how youth with postconcussion syndrome (PCS) are affected by exertion and whether standardized exertion testing using the McMaster All-Out Progressive Continuous Cycling Test can contribute to clinical decision making for safe RTA. Methods Fifty-four youth (8.5-18.3 yr) with a previously confirmed concussion participated in the study. Each participant performed exertion testing on a cycle ergometer and completed a Postconcussion Symptom scale at the following time points: before exertion (baseline), 5 and 30 min, and 24 h after exertion. A modified Postconcussion Symptom scale was administered at 2-min intervals during exertion. Results Participants had a mean ± SD symptom duration of 6.3 ± 6.9 months after the most recent concussive injury, with a median of 4.1 months (range, 0.7-35 months). Sixty-three percent of participants had symptoms during exertion testing. Symptom profile (number and severity) significantly affected perception of exertion at 50% peak mechanical power. During acute assessment of symptoms (30-min after exertion), headache (P = 0.39), nausea (P = 0.63), and dizziness (P = 0.35) did not change. However, both the number and severity of symptoms significantly improved over 24 h, with 56.8% of youth showing improvements. The time from the most recent injury had a significant effect on the symptom score at baseline, 30 min after exertion, and 24 h after exertion. Conclusions Exertion testing has an important role in the evaluation of symptoms and readiness to RTA, particularly in youth who are slow to recover. Overall, controlled exertion seemed to lesson symptoms for most youth. © 2015 by the American College of Sports Medicine.},
keywords = {Adolescent, adolescents, brain concussion, Child, children, Cross-Sectional Studies, cross-sectional study, exercise, exercise test, exercise tolerance, Female, head injury, human, Humans, Male, Pathophysiology, Physical Exertion, Post-Concussion Syndrome, postconcussion syndrome, Return to Play, return to sport, time factor, Time Factors},
pubstate = {published},
tppubtype = {article}
}
Dematteo, Carol; Volterman, Kimberly A; Breithaupt, Peter G; Claridge, Everett A; Adamich, John; Timmons, Brian W
Exertion Testing in Youth with Mild Traumatic Brain Injury/Concussion Journal Article
In: Medicine & Science in Sports & Exercise, vol. 47, no. 11, pp. 2283–2290, 2015, ISBN: 01959131.
Abstract | BibTeX | Tags: *BRAIN -- Concussion, *BRAIN -- Wounds & injuries, *EXERCISE, *EXERCISE tests, *POSTCONCUSSION syndrome, *SPORTS participation, ADOLESCENCE, adolescents, brain concussion, children, DATA analysis, DATA analysis -- Software, DECISION making in clinical medicine, DESCRIPTIVE statistics, head injury, MULTIPLE regression analysis, ONE-way analysis of variance, postconcussion syndrome, RESEARCH -- Finance, Return to Play, SAMPLING (Statistics), STATISTICS
@article{Dematteo2015b,
title = {Exertion Testing in Youth with Mild Traumatic Brain Injury/Concussion},
author = {Dematteo, Carol and Volterman, Kimberly A and Breithaupt, Peter G and Claridge, Everett A and Adamich, John and Timmons, Brian W},
isbn = {01959131},
year = {2015},
date = {2015-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {47},
number = {11},
pages = {2283--2290},
abstract = {Purpose: The decision regarding return to activity (RTA) after mild traumatic brain injuries/concussion is one of the most difficult and controversial areas in concussion management, particularly for youth. This study investigated how youth with postconcussion syndrome (PCS) are affected by exertion and whether standardized exertion testing using the McMaster All-Out Progressive Continuous Cycling Test can contribute to clinical decision making for safe RTA. Methods: Fifty-four youth (8.5-18.3 yr) with a previously confirmed concussion participated in the study. Each participant performed exertion testing on a cycle ergometer and completed a Postconcussion Symptom scale at the following time points: before exertion (baseline), 5 and 30 min, and 24 h after exertion. A modified Postconcussion Symptom scale was administered at 2-min intervals during exertion. Results: Participants had a mean T SD symptom duration of 6.3 T 6.9 months after the most recent concussive injury, with a median of 4.1 months (range, 0.7-35 months). Sixty-three percent of participants had symptoms during exertion testing. Symptom profile (number and severity) significantly affected perception of exertion at 50% peak mechanical power. During acute assessment of symptoms (30-min after exertion), headache (P = 0.39), nausea (P = 0.63), and dizziness (P = 0.35) did not change. However, both the number and severity of symptoms significantly improved over 24 h, with 56.8% of youth showing improvements. The time from the most recent injury had a significant effect on the symptom score at baseline, 30 min after exertion, and 24 h after exertion. Conclusions: Exertion testing has an important role in the evaluation of symptoms and readiness to RTA, particularly in youth who are slow to recover. Overall, controlled exertion seemed to lesson symptoms for most youth. ABSTRACT FROM AUTHOR},
keywords = {*BRAIN -- Concussion, *BRAIN -- Wounds \& injuries, *EXERCISE, *EXERCISE tests, *POSTCONCUSSION syndrome, *SPORTS participation, ADOLESCENCE, adolescents, brain concussion, children, DATA analysis, DATA analysis -- Software, DECISION making in clinical medicine, DESCRIPTIVE statistics, head injury, MULTIPLE regression analysis, ONE-way analysis of variance, postconcussion syndrome, RESEARCH -- Finance, Return to Play, SAMPLING (Statistics), STATISTICS},
pubstate = {published},
tppubtype = {article}
}
Register-Mihalik, J K; De Maio, V J; Tibbo-Valeriote, H L; Wooten, J D
Characteristics of pediatric and adolescent concussion clinic patients with postconcussion amnesia Journal Article
In: Clinical Journal of Sport Medicine, vol. 25, no. 6, pp. 502–508, 2015.
Abstract | BibTeX | Tags: Adolescent, adult, amnesia, anamnesis, Article, brain concussion, Child, complication, Concussion, Concussive injury, Cross-Sectional Studies, cross-sectional study, Demography, disease severity, emergency ward, ethnology, Female, head injury, human, Humans, major clinical study, Male, MEDICAL history taking, Memory, ODDS ratio, outcome assessment, postconcussion symptoms, priority journal, race, Retrospective Studies, retrospective study, Risk, risk factor, Risk Factors, unconsciousness
@article{Register-Mihalik2015,
title = {Characteristics of pediatric and adolescent concussion clinic patients with postconcussion amnesia},
author = {Register-Mihalik, J K and {De Maio}, V J and Tibbo-Valeriote, H L and Wooten, J D},
year = {2015},
date = {2015-01-01},
journal = {Clinical Journal of Sport Medicine},
volume = {25},
number = {6},
pages = {502--508},
abstract = {Objective: The current study examines the demographics, injury characteristics, and outcomes associated with the presence of postconcussion amnesia in young concussion clinic patients. Design: Cross-sectional, retrospective clinical cohort. Setting: Concussion services clinic. Patients: Pediatric and adolescent concussion services program patients, presenting within 10 days postinjury, aged 10-18 years, with the goal of returning to sport (n = 245). Assessment of Risk Factors: Age, gender, race, head trauma history, injury mechanism, loss of consciousness (LOC), injuryrelated visit to an emergency department, cognitive and balance scores, symptoms, and management recommendations. Main Outcome Measures: Univariate and multivariate analyses determined adjusted odds ratios for reported presence of any postconcussion amnesia (anterograde or retrograde). Results: Factors associated with amnesia (univariate, P \< 0.10) and included in the multivariate model were race, head trauma history, mechanism of injury, LOC, injury-related visit to an emergency department, management recommendations and time of injury and initial visit symptom severity. Age and gender were also included in the model due to biological significance. Of the 245 patients, 181 had data for all model variables. Of the 181 patients, 58 reported amnesia. History of head trauma [odds ratio (OR), 2.7; 95% confidence interval (CI), 1.3-5.7]; time of injury (TOI) symptom severity \>75th percentile (OR, 2.6; 95% CI, 1.2-5.3) and LOC (OR, 2.2; 95% CI, 1.1-4.6) were found to have significant and independent relationships with amnesia in the multivariate model. Conclusions: This study illustrates that patients presenting with postconcussion amnesia are more likely to have a history of head trauma, LOC, and greater symptom severity. Future research is needed to better understand amnesia following concussion. Clinical Relevance: Amnesia presence, previous head trauma, LOC, and increased symptom severity may aid in identifying patients with a greater initial injury burden who warrant closer observation and more conservative management. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.},
keywords = {Adolescent, adult, amnesia, anamnesis, Article, brain concussion, Child, complication, Concussion, Concussive injury, Cross-Sectional Studies, cross-sectional study, Demography, disease severity, emergency ward, ethnology, Female, head injury, human, Humans, major clinical study, Male, MEDICAL history taking, Memory, ODDS ratio, outcome assessment, postconcussion symptoms, priority journal, race, Retrospective Studies, retrospective study, Risk, risk factor, Risk Factors, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Merritt, V C; Meyer, J E; Arnett, P A
A novel approach to classifying postconcussion symptoms: The application of a new framework to the Post-Concussion Symptom Scale Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 37, no. 7, pp. 764–775, 2015.
Abstract | Links | BibTeX | Tags: Adolescent, Athletic Injuries, brain concussion, CLASSIFICATION, collegiate athletes, Female, human, Humans, Male, neuropsychological test, Neuropsychological Tests, Post-Concussion Syndrome, postconcussion symptoms, self report, SEVERITY of illness index, Sports-related concussion, symptom assessment, Young Adult
@article{Merritt2015b,
title = {A novel approach to classifying postconcussion symptoms: The application of a new framework to the Post-Concussion Symptom Scale},
author = {Merritt, V C and Meyer, J E and Arnett, P A},
doi = {10.1080/13803395.2015.1060950},
year = {2015},
date = {2015-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {37},
number = {7},
pages = {764--775},
abstract = {Introduction: Self-report measures such as the Post-Concussion Symptom Scale (PCSS) are frequently used during baseline and postconcussion testing to evaluate athletes symptom profiles. However, the common approach of evaluating the total symptom score and/or symptom clusters may not allow for a complete understanding of the nature of athletes symptom reporting patterns. The primary objective of this study was to apply three "global indices of distress" variables, derived from the Symptom Checklist-90-Revised (SCL-90-R) framework, to the PCSS at baseline and postconcussion. We aimed to evaluate the utility of these symptom indices in relation to four PCSS symptom clusters and the total PCSS symptom score. Method: Participants included college athletes evaluated at baseline (N = 846) and postconcussion (N = 86). Athletes underwent neuropsychological testing at both time points, including completion of the PCSS and a paper/pencil and computerized test battery. Eight symptom indices were derived from the PCSS, and a postconcussion neurocognitive composite score was calculated. Results: Results showed that there were significant mean increases from baseline to postconcussion on four of the eight symptom indices evaluated. Furthermore, a significant proportion of athletes showed no change from baseline to postconcussion when evaluating the total symptom score, but showed at least a one standard deviation increase in symptom reporting from baseline to postconcussion when evaluating at least one other symptom index (i.e., a global index of distress or symptom cluster). Finally, the three global indices of distress variables, two of the four symptom clusters, and the total symptom score significantly predicted a postconcussion neurocognitive composite score, such that greater postconcussion symptoms were associated with lower postconcussion neurocognitive performance. Conclusions: These findings suggest that, in addition to evaluating the postconcussion total symptom score, there may be value in examining more specific symptom indices such as the global indices of distress variables and symptom clusters. © 2015 Taylor \& Francis.},
keywords = {Adolescent, Athletic Injuries, brain concussion, CLASSIFICATION, collegiate athletes, Female, human, Humans, Male, neuropsychological test, Neuropsychological Tests, Post-Concussion Syndrome, postconcussion symptoms, self report, SEVERITY of illness index, Sports-related concussion, symptom assessment, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Hendricks, S; O’Connor, S; Lambert, M; Brown, J; Burger, N; Fie, S M; Readhead, C; Viljoen, W
Contact technique and concussions in the South African under-18 Coca-Cola craven week rugby tournament Journal Article
In: European Journal of Sport Science, vol. 15, no. 6, pp. 557–564, 2015.
Abstract | Links | BibTeX | Tags: Athletic Injuries, brain concussion, Concussion, football, human, Humans, Injury and prevention, measurement, PHYSIOLOGY, Skill, team sport, videorecording, Videotape Recording
@article{Hendricks2015,
title = {Contact technique and concussions in the South African under-18 Coca-Cola craven week rugby tournament},
author = {Hendricks, S and O’Connor, S and Lambert, M and Brown, J and Burger, N and Fie, S M and Readhead, C and Viljoen, W},
doi = {10.1080/17461391.2015.1046192},
year = {2015},
date = {2015-01-01},
journal = {European Journal of Sport Science},
volume = {15},
number = {6},
pages = {557--564},
abstract = {In rugby union, understanding the techniques and events leading to concussions is important because of the nature of the injury and the severity and potential long-term consequences, particularly in junior players. Proper contact technique is a prerequisite for successful participation in rugby and is a major factor associated with injury. However, the execution of proper contact technique and its relationship to injury has yet to be studied in matches. Therefore, the aim of this study was to compare contact techniques leading to concussion with a representative sample of similarly matched non-injury (NI) contact events. Injury surveillance was conducted at the 2011-2013 under-18 Craven Week Rugby tournaments. Video footage of 10 concussive events (5 tackle, 4 ruck and 1 aerial collision) and 83 NI events were identified (19 tackle, 61 ruck and 3 aerial collisions). Thereafter, each phase of play was analysed using standardised technical proficiency criteria. Overall score for ruck proficiency in concussive events was 5.67 (out of a total of 15) vs. 6.98 for NI events (n = 54) (effect size = 0.52, small). Overall average score for tackler proficiency was 7.25 (n = 4) and 6.67 (n = 15) for injury and NI tackles, respectively (out of 16) (effect size = 0.19, trivial). This is the first study to compare concussion injury contact technique to a player-matched sample of NI contact techniques. Certain individual technical criteria had an effect towards an NI outcome, and others had an effect towards a concussive event, highlighting that failure to execute certain techniques may substantially increase the opportunity for concussion. © 2015 European College of Sport Science.},
keywords = {Athletic Injuries, brain concussion, Concussion, football, human, Humans, Injury and prevention, measurement, PHYSIOLOGY, Skill, team sport, videorecording, Videotape Recording},
pubstate = {published},
tppubtype = {article}
}
Marinides, Z; Galetta, K M; Andrews, C N; Wilson, J A; Herman, D C; Robinson, C D; Smith, M S; Bentley, B C; Galetta, S L; Balcer, L J; Clugston, J R
Vision testing is additive to the sideline assessment of sports-related concussion Journal Article
In: Neurology: Clinical Practice, vol. 5, no. 1, pp. 25–34, 2015.
Abstract | Links | BibTeX | Tags: Article, athlete, Balance Error Scoring System, brain concussion, clinical assessment, Female, football, human, King Devick Test, major clinical study, Male, priority journal, Soccer, sport injury, Standardized Assessment of Concussion, vision test
@article{Marinides2015,
title = {Vision testing is additive to the sideline assessment of sports-related concussion},
author = {Marinides, Z and Galetta, K M and Andrews, C N and Wilson, J A and Herman, D C and Robinson, C D and Smith, M S and Bentley, B C and Galetta, S L and Balcer, L J and Clugston, J R},
doi = {10.1212/CPJ.0000000000000060},
year = {2015},
date = {2015-01-01},
journal = {Neurology: Clinical Practice},
volume = {5},
number = {1},
pages = {25--34},
abstract = {We examined the King-Devick (K-D) test, a vision-based test of rapid number naming, as a complement to components of the Sport Concussion Assessment Tool, 3rd edition (SCAT3) for diagnosis of concussion. Baseline and postconcussion data for the University of Florida men's football, women's soccer, and women's lacrosse teams were collected, including the K-D test, Standardized Assessment of Concussion (SAC), and Balance Error Scoring System (BESS). Among 30 athletes with first concussion during their athletic season (n 5 217 total), differences from baseline to postinjury showed worsening of K-D time scores in 79%, while SAC showed a ≥2- point worsening in 52%. Combining K-D and SAC captured abnormalities in 89%; adding the BESS identified 100% of concussions. Adding a vision-based test may enhance the detection of athletes with concussion. © 2015 American Academy of Neurology.},
keywords = {Article, athlete, Balance Error Scoring System, brain concussion, clinical assessment, Female, football, human, King Devick Test, major clinical study, Male, priority journal, Soccer, sport injury, Standardized Assessment of Concussion, vision test},
pubstate = {published},
tppubtype = {article}
}
Shumko, Dr John; Toto, Diana
Education on all aspects of a concussion Journal Article
In: Exceptional Parent, vol. 45, no. 8, pp. 36–38, 2015, ISBN: 0046-9157.
BibTeX | Tags: Attitude to Health, brain concussion, Brain Concussion -- Diagnosis, Brain Concussion -- Symptoms, Brain Concussion -- Therapy, Sports Re-Entry
@article{Shumko2015,
title = {Education on all aspects of a concussion},
author = {Shumko, Dr John and Toto, Diana},
isbn = {0046-9157},
year = {2015},
date = {2015-01-01},
journal = {Exceptional Parent},
volume = {45},
number = {8},
pages = {36--38},
keywords = {Attitude to Health, brain concussion, Brain Concussion -- Diagnosis, Brain Concussion -- Symptoms, Brain Concussion -- Therapy, Sports Re-Entry},
pubstate = {published},
tppubtype = {article}
}
McGinley, A D; Master, C L; Zonfrillo, M R
Sports-Related Head Injuries in Adolescents: A Comprehensive Update Journal Article
In: Adolescent Medicine, vol. 26, no. 3, pp. 491–506, 2015.
BibTeX | Tags: Adolescent, Athletic Injuries, brain concussion, Brain Injuries, Brain Injury, Chronic, CONVALESCENCE, human, Humans, injury scale, Recovery of Function, sport injury, Trauma Severity Indices
@article{McGinley2015,
title = {Sports-Related Head Injuries in Adolescents: A Comprehensive Update},
author = {McGinley, A D and Master, C L and Zonfrillo, M R},
year = {2015},
date = {2015-01-01},
journal = {Adolescent Medicine},
volume = {26},
number = {3},
pages = {491--506},
keywords = {Adolescent, Athletic Injuries, brain concussion, Brain Injuries, Brain Injury, Chronic, CONVALESCENCE, human, Humans, injury scale, Recovery of Function, sport injury, Trauma Severity Indices},
pubstate = {published},
tppubtype = {article}
}
Antonius, D; Mathew, N; Picano, J; Hinds, A; Cogswell, A; Olympia, J; Brooks, T; Di Giacomo, M; Baker, J; Willer, B; Leddy, J
In: Journal of Neuropsychiatry and Clinical Neurosciences, vol. 26, no. 4, pp. 313–322, 2014.
Abstract | Links | BibTeX | Tags: Aggression, anxiety disorder, apathy, Article, behavior change, behavior disorder, brain concussion, buspirone, Chronic traumatic encephalopathy, Chronic Traumatic Encephalopathy beta adrenergic r, cingulate gyrus, degenerative disease, depression, euphoria, head injury, human, hypersexuality, impulse control disorder, mental disease, mental instability, mood change, nerve degeneration, neurofibrillary tangle, olanzapine, parahippocampal gyrus, personality disorder, postconcussion syndrome, posttraumatic stress disorder, priority journal, serotonin uptake inhibitor, sexual behavior, suicidal behavior, traumatic brain injury
@article{Antonius2014,
title = {Behavioral health symptoms associated with chronic traumatic encephalopathy: A critical review of the literature and recommendations for treatment and research},
author = {Antonius, D and Mathew, N and Picano, J and Hinds, A and Cogswell, A and Olympia, J and Brooks, T and {Di Giacomo}, M and Baker, J and Willer, B and Leddy, J},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84920996232\&partnerID=40\&md5=cb8a1deab38101900f8d7a8ac0b7a80c},
year = {2014},
date = {2014-01-01},
journal = {Journal of Neuropsychiatry and Clinical Neurosciences},
volume = {26},
number = {4},
pages = {313--322},
abstract = {Chronic traumatic encephalopathy (CTE) is a neurodegenerative syndrome that has been linked to serious psychiatric symptoms, including depression, aggression, and suicidal behavior. This review critically examines the extant research on the behavioral manifestations of CTE and concludes that the paucity of longitudinal prospective studies on CTE, combined with a lack of research-accepted diagnostic criteria for identifying individuals who are considered at risk for CTE, makes it difficult to reliably establish a causal relationship between CTE and the onset of behavioral health problems. Selection and reporting bias and inconsistency in data collection methods are other concerns. To advance the field, there is a critical need for more empirical research on the behavioral manifestations of CTE. Recommendations and intervention models are also discussed. © 2014 American Psychiatric Association.},
keywords = {Aggression, anxiety disorder, apathy, Article, behavior change, behavior disorder, brain concussion, buspirone, Chronic traumatic encephalopathy, Chronic Traumatic Encephalopathy beta adrenergic r, cingulate gyrus, degenerative disease, depression, euphoria, head injury, human, hypersexuality, impulse control disorder, mental disease, mental instability, mood change, nerve degeneration, neurofibrillary tangle, olanzapine, parahippocampal gyrus, personality disorder, postconcussion syndrome, posttraumatic stress disorder, priority journal, serotonin uptake inhibitor, sexual behavior, suicidal behavior, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Miyashita, Theresa L; Diakogeorgiou, Eleni; Hellstrom, Brian; Kuchwara, Nick; Tafoya, Erica; Lori, Young
High School Athletes' Perceptions of Concussion Journal Article
In: Orthopaedic Journal of Sports Medicine, pp. 1–5, 2014.
Links | BibTeX | Tags: ADOLESCENCE, ANALYSIS of variance, Athletes, Athletic, Athletic Training, attitude, brain concussion, Coaches, Cross Sectional Studies, Data Analysis Software, DESCRIPTIVE statistics, Female, Head Injuries, health education, Health Knowledge, high school, human, Male, Random Sample, T-Tests
@article{Miyashita2014,
title = {High School Athletes' Perceptions of Concussion},
author = {Miyashita, Theresa L and Diakogeorgiou, Eleni and Hellstrom, Brian and Kuchwara, Nick and Tafoya, Erica and Lori, Young},
doi = {10.1177/2325967114554549},
year = {2014},
date = {2014-01-01},
journal = {Orthopaedic Journal of Sports Medicine},
pages = {1--5},
publisher = {Sage Publications Inc.},
address = {Thousand Oaks, California},
keywords = {ADOLESCENCE, ANALYSIS of variance, Athletes, Athletic, Athletic Training, attitude, brain concussion, Coaches, Cross Sectional Studies, Data Analysis Software, DESCRIPTIVE statistics, Female, Head Injuries, health education, Health Knowledge, high school, human, Male, Random Sample, T-Tests},
pubstate = {published},
tppubtype = {article}
}
Anonymous,
SCAT3 Journal Article
In: British Journal of Sports Medicine, vol. 47, no. 5, pp. 259, 2013, ISBN: 1473-0480.
BibTeX | Tags: Assessment/Testing article, ataxia, body equilibrium, brain concussion, cognitive defect, emergency treatment, human, injury scale, memory disorder, METHODOLOGY, neurologic examination, neuropsychological test, Physical Examination, questionnaire, sport injury, unconsciousness
@article{Anonymous2013b,
title = {SCAT3},
author = {Anonymous},
isbn = {1473-0480},
year = {2013},
date = {2013-01-01},
journal = {British Journal of Sports Medicine},
volume = {47},
number = {5},
pages = {259},
keywords = {Assessment/Testing article, ataxia, body equilibrium, brain concussion, cognitive defect, emergency treatment, human, injury scale, memory disorder, METHODOLOGY, neurologic examination, neuropsychological test, Physical Examination, questionnaire, sport injury, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Apps, Jennifer Niskala
Review of Ahead of the game: The parent’s guide to youth sports concussion Journal Article
In: Archives of Clinical Neuropsychology, vol. 28, no. 8, pp. 867–868, 2013, ISBN: 0887-6177 1873-5843.
Abstract | Links | BibTeX | Tags: 2013, At Risk Populations, Athletes, brain concussion, health education, parent guide, Parents, sport concussion, Sports, youth athletics
@article{Apps2013,
title = {Review of Ahead of the game: The parent’s guide to youth sports concussion},
author = {Apps, Jennifer Niskala},
doi = {10.1093/arclin/act059},
isbn = {0887-6177
1873-5843},
year = {2013},
date = {2013-01-01},
journal = {Archives of Clinical Neuropsychology},
volume = {28},
number = {8},
pages = {867--868},
publisher = {Oxford University Press},
address = {United Kingdom},
abstract = {Reviews the book, Ahead of the Game: The Parent's Guide to Youth Sports Concussion by Rosemarie Scolaro Moser (2012). This book is a strong addition to the limited arsenal of useful references to help guide parents through the complex maze of information about concussion in youths. The author presents this text in an easily navigable format, with user-friendly titles and terms. While the content of the book may be intimidating for many parents, the format and writing style will not be overwhelming. Additionally, each chapter provides a review at the end, as well as useful tips, facts, and tables throughout. Parents in the midst of trying to educate themselves about this injury, preferably before they are faced with these issues, would likely be able to access individual components of the book as needed. This resource should be useful for parents and the public, as well as clinical neuropsychologists as a possible reference point for parents, community groups, and patient populations. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, At Risk Populations, Athletes, brain concussion, health education, parent guide, Parents, sport concussion, Sports, youth athletics},
pubstate = {published},
tppubtype = {article}
}
Anonymous,
Pocket CRT Journal Article
In: British Journal of Sports Medicine, vol. 47, no. 5, pp. 267, 2013, ISBN: 1473-0480.
BibTeX | Tags: ambulatory care, Article, Assessment/Testing, brain concussion, human, injury scale, memory disorder, sport injury
@article{Anonymous2013a,
title = {Pocket CRT},
author = {Anonymous},
isbn = {1473-0480},
year = {2013},
date = {2013-01-01},
journal = {British Journal of Sports Medicine},
volume = {47},
number = {5},
pages = {267},
keywords = {ambulatory care, Article, Assessment/Testing, brain concussion, human, injury scale, memory disorder, sport injury},
pubstate = {published},
tppubtype = {article}
}
Vagnozzi, Roberto; Signoretti, Stefano; Cristofori, Luciano; Alessandrini, Franco; Floris, Roberto; Isgrò, Eugenio; Ria, Antonio; Marziali, Simone; Zoccatelli, Giada; Tavazzi, Barbara; Del Bolgia, Franco; Sorge, Roberto; Broglio, Steven P; McIntosh, Tracy K; Lazzarino, Giuseppe
Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients: Corrigendum Journal Article
In: Brain: A Journal of Neurology, vol. 136, no. 11, pp. e262–e262, 2013, ISBN: 0006-8950 1460-2156.
Abstract | BibTeX | Tags: 2013, Athletes, brain concussion, BRAIN damage, Concussion, Magnetic Resonance Spectroscopy, metabolic brain damage, mild traumatic brain injury, NEUROCHEMISTRY, Recovery, Recovery (Disorders), Spectroscopy, traumatic brain injury
@article{Vagnozzi2013a,
title = {Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients: Corrigendum},
author = {Vagnozzi, Roberto and Signoretti, Stefano and Cristofori, Luciano and Alessandrini, Franco and Floris, Roberto and Isgr\`{o}, Eugenio and Ria, Antonio and Marziali, Simone and Zoccatelli, Giada and Tavazzi, Barbara and {Del Bolgia}, Franco and Sorge, Roberto and Broglio, Steven P and McIntosh, Tracy K and Lazzarino, Giuseppe},
isbn = {0006-8950
1460-2156},
year = {2013},
date = {2013-01-01},
journal = {Brain: A Journal of Neurology},
volume = {136},
number = {11},
pages = {e262--e262},
abstract = {Reports an error in 'Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients' by Roberto Vagnozzi, Stefano Signoretti, Luciano Cristofori, Franco Alessandrini, Roberto Floris, Eugenio Isgr\`{o}, Antonio Ria, Simone Marziale, Giada Zoccatelli, Barbara Tavazzi, Franco Del Bolgia, Roberto Sorge, Steven P. Broglio, Tracy K. McIntosh and Giuseppe Lazzarino (Brain: A Journal of Neurology, 2010[Nov], Vol 133[11], 3232-3242). In the original article, the eighth author’s surname was incorrectly given as ‘Marziale’. The corrected surname of the eighth author is present in the erratum. (The following abstract of the original article appeared in record [rid]2010-23062-009[/rid]). Concussive head injury opens a temporary window of brain vulnerability due to the impairment of cellular energetic metabolism. As experimentally demonstrated, a second mild injury occurring during this period can lead to severe brain damage, a condition clinically described as the second impact syndrome. To corroborate the validity of proton magnetic resonance spectroscopy in monitoring cerebral metabolic changes following mild traumatic brain injury, apart from the magnetic field strength (1.5 or 3.0 T) and mode of acquisition, we undertook a multicentre prospective study in which a cohort of 40 athletes suffering from concussion and a group of 30 control healthy subjects were admitted. Athletes (aged 16\textendash35 years) were recruited and examined at three different institutions between September 2007 and June 2009. They underwent assessment of brain metabolism at 3, 15, 22 and 30 days post-injury through proton magnetic resonance spectroscopy for the determination of N-acetylaspartate, creatine and choline-containing compounds. Values of these representative brain metabolites were compared with those observed in the group of non-injured controls. Comparison of spectroscopic data, obtained in controls using different field strength and/or mode of acquisition, did not show any difference in the brain metabolite ratios. Athletes with concussion exhibited the most significant alteration of metabolite ratios at Day 3 post-injury (N-acetylaspartate/creatine: −17.6%, N-acetylaspartate/choline: −21.4%; P \< 0.001 with respect to controls). On average, metabolic disturbance gradually recovered, initially in a slow fashion and, following Day 15, more rapidly. At 30 days post-injury, all athletes showed complete recovery, having metabolite ratios returned to values detected in controls. Athletes self-declared symptom clearance between 3 and 15 days after concussion. Results indicate that N-acetylaspartate determination by proton magnetic resonance spectroscopy represents a non-invasive tool to accurately measure changes in cerebral energy metabolism occurring in mild traumatic brain injury. In particular, this metabolic evaluation may significantly improve, along with other clinical assessments, the management of athletes suffering from concussion. Further studies to verify the effects of a second concussive event occurring at different time points of the recovery curve of brain metabolism are needed. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, Athletes, brain concussion, BRAIN damage, Concussion, Magnetic Resonance Spectroscopy, metabolic brain damage, mild traumatic brain injury, NEUROCHEMISTRY, Recovery, Recovery (Disorders), Spectroscopy, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Duhaime, A C
Response Journal Article
In: Journal of Neurosurgery, vol. 117, no. 6, pp. 1090–1091, 2012, ISBN: 0022-3085 1933-0693.
BibTeX | Tags: Accident prevention, Assessment & Testing, athlete, Biomechanics, brain concussion, Equipment, headache, Helmets, human, Neck pain, neurosurgery, Note, Post-Concussion, priority journal, sport injury, surgeon, symptom, Syndrome, traumatic brain injury, unconsciousness
@article{Duhaime2012,
title = {Response},
author = {Duhaime, A C},
isbn = {0022-3085
1933-0693},
year = {2012},
date = {2012-01-01},
journal = {Journal of Neurosurgery},
volume = {117},
number = {6},
pages = {1090--1091},
keywords = {Accident prevention, Assessment \& Testing, athlete, Biomechanics, brain concussion, Equipment, headache, Helmets, human, Neck pain, neurosurgery, Note, Post-Concussion, priority journal, sport injury, surgeon, symptom, Syndrome, traumatic brain injury, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Rabb, C H
Comments Journal Article
In: Neurosurgery, vol. 67, no. 4, pp. 1027–1028, 2010, ISBN: 0148-396X.
BibTeX | Tags: brain concussion, functional magnetic resonance imaging, human, Imaging & EEG, mental task, neuroimaging, Note, priority journal, sport injury, working memory Overviews
@article{Rabb2010,
title = {Comments},
author = {Rabb, C H},
isbn = {0148-396X},
year = {2010},
date = {2010-01-01},
journal = {Neurosurgery},
volume = {67},
number = {4},
pages = {1027--1028},
keywords = {brain concussion, functional magnetic resonance imaging, human, Imaging \& EEG, mental task, neuroimaging, Note, priority journal, sport injury, working memory Overviews},
pubstate = {published},
tppubtype = {article}
}
Pangilinan, P H; Hornyak, J E
Controversial topic: return to competitive sport after severe traumatic brain injury Journal Article
In: Brain Injury, vol. 21, no. 12, pp. 1315–1317, 2007, ISBN: 0269-9052.
Abstract | BibTeX | Tags: Athletes, brain concussion, Brain Injuries -- Rehabilitation, Case Studies, human, Severity of Injury, Sports, Sports Re-Entry
@article{Pangilinan2007,
title = {Controversial topic: return to competitive sport after severe traumatic brain injury},
author = {Pangilinan, P H and Hornyak, J E},
isbn = {0269-9052},
year = {2007},
date = {2007-01-01},
journal = {Brain Injury},
volume = {21},
number = {12},
pages = {1315--1317},
publisher = {Taylor \& Francis Ltd},
address = {Philadelphia, Pennsylvania},
abstract = {Various guidelines have been proposed for returning to sport after concussion or mild TBI. However, no such guidelines exist for severe TBI. This study presents three cases of athletes who sustained severe TBIs and returned to competition. The rational for their clearance will be discussed.},
keywords = {Athletes, brain concussion, Brain Injuries -- Rehabilitation, Case Studies, human, Severity of Injury, Sports, Sports Re-Entry},
pubstate = {published},
tppubtype = {article}
}
Barr, William B
Recovering from mild traumatic brain injury: What psychology has learned from sports concussion research Journal Article
In: NYS Psychologist, vol. 19, no. 5, pp. 24–29, 2007, ISBN: 1048-6925.
Abstract | BibTeX | Tags: 2007, brain concussion, disorder recovery, mild traumatic brain injury, psychology, Recovery (Disorders), Sports, sports concussion, traumatic brain injury
@article{Barr2007,
title = {Recovering from mild traumatic brain injury: What psychology has learned from sports concussion research},
author = {Barr, William B},
isbn = {1048-6925},
year = {2007},
date = {2007-01-01},
journal = {NYS Psychologist},
volume = {19},
number = {5},
pages = {24--29},
publisher = {New York State Psychological Assn},
address = {US},
abstract = {Research on sports concussion has contributed significantly to our knowledge on the characteristics and course of recovery from mild traumatic brain injury (MTBI). Findings from research studies on injured athletes indicate that most symptoms of concussion resolve within 7-10 days of the injury. Results from studies examining the development of more persistent symptoms have found relationships with a number of psychological factors, including expectation and maladaptive coping styles. Systematic reviews of intervention strategies have indicated that psychological approaches to treatment of MTBI, such as early education and support, are more effective than any form of drug treatment. Psychologists should be aware of these findings and the potential for playing a significant role in treating individuals with MTBI. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2007, brain concussion, disorder recovery, mild traumatic brain injury, psychology, Recovery (Disorders), Sports, sports concussion, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Quintana, E C
[Commentary on] Recovery from mild concussion in high school athletes Journal Article
In: Annals of Emergency Medicine, vol. 43, no. 5, pp. 680–681, 2004, ISBN: 0196-0644.
BibTeX | Tags: Athletes, brain concussion, Cognition Disorders -- Etiology, high school, Recovery
@article{Quintana2004,
title = {[Commentary on] Recovery from mild concussion in high school athletes},
author = {Quintana, E C},
isbn = {0196-0644},
year = {2004},
date = {2004-01-01},
journal = {Annals of Emergency Medicine},
volume = {43},
number = {5},
pages = {680--681},
publisher = {Elsevier Science},
address = {New York, New York},
keywords = {Athletes, brain concussion, Cognition Disorders -- Etiology, high school, Recovery},
pubstate = {published},
tppubtype = {article}
}
Bernstein, Daniel M
Information processing difficulty long after self-reported concussion Journal Article
In: Journal of the International Neuropsychological Society, vol. 8, no. 5, pp. 673–682, 2002, ISBN: 1355-6177 1469-7661.
Abstract | Links | BibTeX | Tags: 2002, attention, attention tasks, brain concussion, Cognitive Ability, cognitive tasks, information processing, Mild head injury, self-report concussion
@article{Bernstein2002,
title = {Information processing difficulty long after self-reported concussion},
author = {Bernstein, Daniel M},
doi = {10.1017/S1355617702801400},
isbn = {1355-6177
1469-7661},
year = {2002},
date = {2002-01-01},
journal = {Journal of the International Neuropsychological Society},
volume = {8},
number = {5},
pages = {673--682},
publisher = {Cambridge University Press},
address = {United Kingdom},
abstract = {The present study replicates and extends previous work in which university students with self-reported concussion demonstrated reduced P300 amplitude on a set of easy and difficult attention tasks, in addition to performing more poorly than controls on demanding cognitive tasks many years after injury. In the present study, 13 students with self-reported concussion (MHI group: M time since injury = 8 years) and 10 controls were matched for age, sex, education, and a variety of cognitive, physical and emotional complaints. Controls outperformed the MHI group on the Digit Symbol substitution task and on a difficult dual task involving tone discrimination and visual working memory. Additionally, controls exhibited larger P300 amplitudes on both an easy and a difficult auditory discrimination task. A combination of electrophysiological, neuropsychological and self-report indices predicted group membership (MHI vs. control) with 88% accuracy. The present results, coupled with previous work, offer preliminary evidence that the combination of event-related potentials and demanding behavioral measures might reveal long-lasting, subtle cognitive problems associated with MHI. These findings may challenge existing notions of complete recovery after MHI. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2002, attention, attention tasks, brain concussion, Cognitive Ability, cognitive tasks, information processing, Mild head injury, self-report concussion},
pubstate = {published},
tppubtype = {article}
}
Silverberg, N D; Berkner, P D; Atkins, J E; Zafonte, R; Iverson, G L
Relationship between Short Sleep Duration and Preseason Concussion Testing Journal Article
In: Clinical Journal of Sport Medicine, vol. 26, no. 3, pp. 226–231, 2016.
@article{Silverberg2016,
title = {Relationship between Short Sleep Duration and Preseason Concussion Testing},
author = {Silverberg, N D and Berkner, P D and Atkins, J E and Zafonte, R and Iverson, G L},
doi = {10.1097/JSM.0000000000000241},
year = {2016},
date = {2016-01-01},
journal = {Clinical Journal of Sport Medicine},
volume = {26},
number = {3},
pages = {226--231},
abstract = {Objective: Baseline, preseason assessment of cognition, symptoms, and balance has been recommended as part of a comprehensive sport concussion management program. We examined the relationship between sleep and baseline test results. We hypothesized that adolescents who slept fewer hours the night before would report more symptoms and perform more poorly on cognitive testing than students who had a full night sleep. Design: Cross-sectional observation study. Setting: Preseason concussion testing for high school athletes. Participants: A large sample (n 2928) of student athletes from Maine, USA, between the ages of 13 and 18 years completed preseason testing. Participants with developmental problems, a history of treatment for neurological or psychiatric problems, recent concussion, or 3 or more prior concussions were excluded. Assessment of Risk Factors: Athletes were divided into 4 groups based on their sleep duration the night before testing. Main Outcome Measures: Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT; ImPACT Applications, Inc, Pittsburgh, PA) cognitive composite scores and the embedded Post-Concussion Symptom Scale. Results: Sleep was not related to any ImPACT cognitive composite score, after covarying for age and controlling for multiple comparisons. In contrast, there were sleep duration, sex, and sleep duration by sex effects on the Post-Concussion Symptom Scale. The effect of sleep duration on symptom reporting was more pronounced in girls. Supplementary analyses suggested that sleep insufficiency was associated with a diverse array of postconcussion-like symptoms. Conclusions: Poor sleep the night before baseline or postinjury testing may be an important confound when assessing postconcussion symptoms. Girls may be more vulnerable to experiencing and reporting symptoms following insufficient sleep. Clinical Relevance: Clinicians should routinely ask how the athlete slept the night before preseason baseline testing and consider deferring the symptom assessment or later retesting athletes who slept poorly. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Laker, S R; Meron, A; Greher, M R; Wilson, J
Retirement and Activity Restrictions Following Concussion Journal Article
In: Physical Medicine & Rehabilitation Clinics of North America, vol. 27, no. 2, pp. 487–501, 2016.
@article{Laker2016,
title = {Retirement and Activity Restrictions Following Concussion},
author = {Laker, S R and Meron, A and Greher, M R and Wilson, J},
doi = {10.1016/j.pmr.2016.01.001},
year = {2016},
date = {2016-01-01},
journal = {Physical Medicine \& Rehabilitation Clinics of North America},
volume = {27},
number = {2},
pages = {487--501},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Brauge, D; Moulin, B; Lafargue, M; Nogué, E; Rivière, D; Pariente, J
Brain concusion in Midi-Pyrénées amateur rugby Journal Article
In: Science and Sports, vol. 31, no. 5, pp. 297–302, 2016.
@article{Brauge2016,
title = {Brain concusion in Midi-Pyr\'{e}n\'{e}es amateur rugby},
author = {Brauge, D and Moulin, B and Lafargue, M and Nogu\'{e}, E and Rivi\`{e}re, D and Pariente, J},
doi = {10.1016/j.scispo.2016.04.009},
year = {2016},
date = {2016-01-01},
journal = {Science and Sports},
volume = {31},
number = {5},
pages = {297--302},
abstract = {Objective Concussion could provide disabling consequences if repetitive. We would like to assess the state of knowledge of this problem in Midi-Pyr\'{e}n\'{e}es amateur rugby. Material and methods Our evaluation was based on questionnaire about diagnosis and management of concussion. For each club, we included at least one player and one staff member (manager, medical team member or coach). Results One hundred and sixty-three subjects (37 players and 126 staff members) of 47 clubs were included. For all subjects, the loss of conscious was a symptom of concussion but only 61% could give 3 others symptoms. The risk of a second accident during days after concussion was known by 95%. About primary care, 50% did not look for cervical spine accident just after brain concussion and 22% thought that concussed athletes could finish the game. A majority of our study population (89%) would not leave alone an injured player after the trauma. This study shows some deficiencies in identification of concussion. The questions about primary care indicate some problems that can cause additional accident. © 2016},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Holtkamp, M D; Grimes, J; Ling, G
Concussion in the Military: an Evidence-Base Review of mTBI in US Military Personnel Focused on Posttraumatic Headache Journal Article
In: Current Pain & Headache Reports, vol. 20, no. 6, 2016.
@article{Holtkamp2016,
title = {Concussion in the Military: an Evidence-Base Review of mTBI in US Military Personnel Focused on Posttraumatic Headache},
author = {Holtkamp, M D and Grimes, J and Ling, G},
doi = {10.1007/s11916-016-0572-x},
year = {2016},
date = {2016-01-01},
journal = {Current Pain \& Headache Reports},
volume = {20},
number = {6},
abstract = {Traumatic brain injury (TBI) is defined as an alteration in brain function caused by an external force. Mild TBI or concussion is now well recognized to be a risk of military service as well as participation in athletic sports such as football. Posttraumatic headache (PTH) is the most common symptom after mTBI in US service members. PTH most commonly presents with migraine-like headache features. The following is an overview of the epidemiology, pathophysiology, clinical course, prognosis, complications, and treatment of mTBI and associated comorbidities with a focus on PTH. There is a particular emphasis on emerging evidence-based clinical practice. One important medical consequence of the recognition that mTBI is a highly prevalent among military service members is that the Department of Defense (DoD) is dedicating significant financial and intellectual resources to better understanding and developing treatments for TBI. The identification of the importance of TBI among the US military population has had the added benefit of increasing awareness of this condition among civilian populations, particularly those engaged in both professional and youth sports. The NIH and NSF are also supporting important TBI research. President Obama’s Brain Initiative is also providing additional impetus for these efforts. Unfortunately, the understanding of the acute and chronic effects of mTBI on the brain remains limited. Gratefully, there is hope that through innovative research, there will be advances in elucidating the underlying pathophysiology, which will lead to clinical and prognostic indicators, ultimately resulting in new treatment options for this very complicated set of disorders. © 2016, Springer Science+Business Media New York (outside the USA).},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gardner, A J; Tan, C O; Ainslie, P N; Van Donkelaar, P; Stanwell, P; Levi, C R; Iverson, G L
Cerebrovascular reactivity assessed by transcranial Doppler ultrasound in sport-related concussion: A systematic review Journal Article
In: British Journal of Sports Medicine, vol. 49, no. 16, pp. 1050–1055, 2015.
@article{Gardner2015bb,
title = {Cerebrovascular reactivity assessed by transcranial Doppler ultrasound in sport-related concussion: A systematic review},
author = {Gardner, A J and Tan, C O and Ainslie, P N and {Van Donkelaar}, P and Stanwell, P and Levi, C R and Iverson, G L},
doi = {10.1136/bjsports-2014-093901},
year = {2015},
date = {2015-01-01},
journal = {British Journal of Sports Medicine},
volume = {49},
number = {16},
pages = {1050--1055},
abstract = {Background: Traumatic brain injury influences regulation of cerebral blood flow in animal models and in human studies. We reviewed the use of transcranial Doppler ultrasound (US) to monitor cerebrovascular reactivity following sport-related concussion. Review method: A narrative and systematic review of articles published in the English language, from December 1982 to October 2013. Data sources: Articles were retrieved via numerous databases using relevant key terms. Observational, cohort, correlational, cross-sectional and longitudinal studies were included. Results: Three publications met the criteria for inclusion; these provided data from 42 athletes and 33 controls. All three studies reported reductions in cerebrovascular reactivity via transcranial Doppler US. Conclusions: These initial results support the use of cerebrovascular reactivity as a research tool for identifying altered neurophysiology and monitoring recovery in adult athletes. Larger cross-sectional, prospective and longitudinal studies are required to understand the sensitivity and prognostic value of cerebrovascular reactivity in sport-related concussion. © 2015, BMJ Publishing Group. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Zottoli, T M; Hoover, S; Barr, W B
In: Clinical Neuropsychologist, vol. 29, no. 5, pp. 678–688, 2015.
@article{Zottoli2015,
title = {Utility of the Standardized Assessment of Concussion (SAC) to Detect Insufficient Effort in Independent Medical Examinations and Civil Litigation Cases},
author = {Zottoli, T M and Hoover, S and Barr, W B},
doi = {10.1080/13854046.2015.1062562},
year = {2015},
date = {2015-01-01},
journal = {Clinical Neuropsychologist},
volume = {29},
number = {5},
pages = {678--688},
abstract = {Objective: The Standardized Assessment of Concussion (SAC) is a standardized mental status screening instrument initially developed for assessment and tracking of concussion symptoms in athletes. The purpose of the current study was to validate the utility of the SAC as an embedded screening measure for insufficient effort in independent medical examinations (IME) and personal injury cases. Method: A known-groups design was used to examine the SACs utility for the detection of insufficient effort in 75 de-identified private IME and civil litigation evaluations. Initial classifications of insufficient effort were made independently of SAC scores, on the basis of having two or more scores falling below established cut-offs on previously validated neuropsychological measures. Results: Results suggest that the total score on the SAC significantly distinguishes effortful respondents from those exhibiting insufficient effort. Empirically derived cut-off scores yielded adequate sensitivity (.62-.95) and negative predictive power (.93-.97). Conclusions: While optimal cut-off scores depend upon intended use, our data suggest that the SAC is useful as a potential screener for insufficient effort, after which one can employ additional measures to rule out false-positives. Further research is required before cut-off scores can be recommended for clinical use. © 2015 Taylor and Francis.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Fuller, C W; Jones, R; Fuller, A D
Defining a safe player run-off zone around rugby union playing areas Journal Article
In: Injury Prevention, vol. 21, no. 5, pp. 309–313, 2015.
@article{Fuller2015ab,
title = {Defining a safe player run-off zone around rugby union playing areas},
author = {Fuller, C W and Jones, R and Fuller, A D},
doi = {10.1136/injuryprev-2015-041587},
year = {2015},
date = {2015-01-01},
journal = {Injury Prevention},
volume = {21},
number = {5},
pages = {309--313},
abstract = {Objectives To identify the circumstances in which international rugby players exit the playing area during match activities and to define a safe run-off distance around the playing area. Method An observational study using video recordings of 102 matches associated with the Rugby World Cup (2011), Rugby Championship (2013, 2014) and Six Nations Championship (2013, 2014) were used to analyse every event in which one or more players exited the playing area during normal match activities. The circumstances in which a player exited the playing area were categorised using a range of parameters: playing position, location, out-of-play region, match activity, distance travelled over the touchline, contacts made with pitchside fixtures and fittings. Results Ninety-five per cent of player-excursions took place within 5.2 m of the touchline. Players exiting the playing area were nearly three times more likely to be a back than a forward (p\<0.001) and the event was more likely to take place when a team was defending than attacking (p\<0.001). Being forced out of play during a contact event (70%) was the major reason for players exiting the playing area. Most players (88%) exiting the playing area only made contact with the perimeter area surface; a small proportion of players contacted touchline flags (6.1%), advertising boards (2.3%) and TV cameras/equipment (1.0%). Conclusions A minimum hazard-free distance of 5 m around a Rugby pitch is proposed based on the 95% percentile frequency distribution of player-excursion events into the areas contiguous with the playing area. © 2015 BMJ Publishing Group. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Phillips, S; Woessner, D
Sports-Related Traumatic Brain Injury Journal Article
In: Primary Care - Clinics in Office Practice, vol. 42, no. 2, pp. 243–248, 2015.
@article{Phillips2015b,
title = {Sports-Related Traumatic Brain Injury},
author = {Phillips, S and Woessner, D},
doi = {10.1016/j.pop.2015.01.010},
year = {2015},
date = {2015-01-01},
journal = {Primary Care - Clinics in Office Practice},
volume = {42},
number = {2},
pages = {243--248},
abstract = {Concussions have garnered more attention in the medical literature, media, and social media. As such, in the nomenclature according to the Centers for Disease Control and Prevention, the term concussion has been supplanted by the term mild traumatic brain injury. Current numbers indicate that 1.7 million TBIs are documented annually, with estimates around 3 million annually (173,285 sports- and recreation-related TBIs among children and adolescents). The Sideline Concussion Assessment Tool 3 and the NFL Sideline Concussion Assessment Tool are commonly used sideline tools. © 2015 Elsevier Inc.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
DiFazio, M; Silverberg, N D; Kirkwood, M W; Bernier, R; Iverson, G L
Prolonged Activity Restriction after Concussion: Are We Worsening Outcomes? Journal Article
In: Clinical Pediatrics, vol. 55, no. 5, pp. 443–451, 2015.
@article{DiFazio2015,
title = {Prolonged Activity Restriction after Concussion: Are We Worsening Outcomes?},
author = {DiFazio, M and Silverberg, N D and Kirkwood, M W and Bernier, R and Iverson, G L},
doi = {10.1177/0009922815589914},
year = {2015},
date = {2015-01-01},
journal = {Clinical Pediatrics},
volume = {55},
number = {5},
pages = {443--451},
abstract = {The current treatment of concussion or mild traumatic brain injury (mTBI) is primarily based on expert consensus. Most clinical practice guidelines advise cognitive and physical rest after injury including withdrawal from normal life activities such as school attendance, sports participation, and technology use until symptoms resolve. Some individuals who sustain an mTBI experience persistent physical, cognitive, and mental health problems. Activity restriction itself may contribute to protracted recovery and other complications. Williamson's Activity Restriction Model of Depression, formulated more than 20 years ago, is central to this hypothesis. We review research evidence for potential harms of prolonged activity restriction and report an mTBI case as an example of how an "activity restriction cascade" can unfold. According to this model, psychological consequences of removal from validating life activities, combined with physical deconditioning, contribute to the development and persistence of postconcussive symptoms after mTBI in some youth. A modification to mTBI guidelines that emphasizes prompt reengagement in life activities as tolerated is encouraged. © SAGE Publications.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Wang, H; Wang, B; Jackson, K; Miller, C M; Hasadsri, L; Llano, D; Rubin, R; Zimmerman, J; Johnson, C; Sutton, B
A novel head-neck cooling device for concussion injury in contact sports Journal Article
In: Translational Neuroscience, vol. 6, pp. 20–31, 2015.
@article{Wang2015a,
title = {A novel head-neck cooling device for concussion injury in contact sports},
author = {Wang, H and Wang, B and Jackson, K and Miller, C M and Hasadsri, L and Llano, D and Rubin, R and Zimmerman, J and Johnson, C and Sutton, B},
doi = {10.1515/tnsci-2015-0004},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
pages = {20--31},
abstract = {Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports. © 2015 Huan Wang et al., licensee De Gruyter Open.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Maerlender, A; Rieman, W; Lichtenstein, J; Condiracci, C
Programmed physical exertion in recovery from sports-related concussion: A randomized pilot study Journal Article
In: Developmental Neuropsychology, vol. 40, no. 5, pp. 273–278, 2015.
@article{Maerlender2015a,
title = {Programmed physical exertion in recovery from sports-related concussion: A randomized pilot study},
author = {Maerlender, A and Rieman, W and Lichtenstein, J and Condiracci, C},
doi = {10.1080/87565641.2015.1067706},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {5},
pages = {273--278},
abstract = {Although no data exist, general practice recommends only rest following concussion. This randomized clinical trial found that programmed physical exertion during recovery produced no significant differences in recovery time between groups of participants. However, high levels of exertion were deleterious. This study provides initial evidence that moderate physical activity is a safe replacement behavior during recovery. © 2015 Copyright © 2015 Taylor \& Francis Group, LLC.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Neal, Timothy L; Diamond, Alex B; Goldman, Scott; Liedtka, Karl D; Mathis, Kembra; Morse, Eric D; Putukian, Margot; Quandt, Eric; Ritter, Stacey J; Sullivan, John P; Welzant, Victor
In: Journal of Athletic Training, vol. 50, no. 3, pp. 231–249, 2015, ISBN: 1062-6050.
@article{Neal2015,
title = {Interassociation Recommendations for Developing a Plan to Recognize and Refer Student-Athletes With Psychological Concerns at the Secondary School Level: A Consensus Statement},
author = {Neal, Timothy L and Diamond, Alex B and Goldman, Scott and Liedtka, Karl D and Mathis, Kembra and Morse, Eric D and Putukian, Margot and Quandt, Eric and Ritter, Stacey J and Sullivan, John P and Welzant, Victor},
doi = {10.4085/1062-6050-50.3.03},
isbn = {1062-6050},
year = {2015},
date = {2015-01-01},
journal = {Journal of Athletic Training},
volume = {50},
number = {3},
pages = {231--249},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Sikoglu, E M; Liso Navarro, A A; Czerniak, S M; McCafferty, J; Eisenstock, J; Stevenson, J H; King, J A; Moore, C M
Effects of Recent Concussion on Brain Bioenergetics: A Phosphorus-31 Magnetic Resonance Spectroscopy Study Journal Article
In: Cognitive and Behavioral Neurology, vol. 28, no. 4, pp. 181–187, 2015.
@article{Sikoglu2015,
title = {Effects of Recent Concussion on Brain Bioenergetics: A Phosphorus-31 Magnetic Resonance Spectroscopy Study},
author = {Sikoglu, E M and {Liso Navarro}, A A and Czerniak, S M and McCafferty, J and Eisenstock, J and Stevenson, J H and King, J A and Moore, C M},
doi = {10.1097/WNN.0000000000000076},
year = {2015},
date = {2015-01-01},
journal = {Cognitive and Behavioral Neurology},
volume = {28},
number = {4},
pages = {181--187},
abstract = {Background: Although clinical evaluations and neurocognitive assessments are commonly used to evaluate the extent of and recovery from concussion, brain bioenergetics could provide a more quantitative marker. The neurometabolic response to a concussion is thought to increase neuronal energy consumption and thus the demand for nucleoside triphosphate (NTP). Objective: We investigated the possible disruption in high-energy metabolism within the prefrontal cortex of college athletes who had either had a concussion within the past 6 months (n=14) or had never had a concussion (n=13). We hypothesized that concussed athletes would have imbalanced brain bioenergetics resulting from increased NTP consumption, and these biochemical changes would correspond to impaired cognitive abilities. Methods: We used phosphorus-31 magnetic resonance spectroscopy to quantify high-energy phosphates. We performed the neuroimaging in conjunction with neurocognitive assessments targeting prefrontal cortex-mediated tasks. Results: Our results revealed significantly lower $gamma$-NTP levels in the athletes after concussion. Although the concussed and non-concussed participants performed similarly in neurocognitive assessments, lower levels of $gamma$-NTP were associated with worse scores on neurocognitive tasks. Conclusions: Our results support the concept of increased energy demand in the prefrontal cortex of a concussed brain, and we found that while neurocognitive assessments appear normal, brain energetics may be abnormal. A longitudinal study could help establish brain NTP levels as a biomarker to aid in diagnosis and to assess recovery in concussed patients. © 2015 Wolters Kluwer Health, Inc.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Liu, C Y; Law, M; Romano, R
Rational approach to understanding and preventing sports-related traumatic brain injuries Journal Article
In: World Neurosurgery, vol. 84, no. 6, pp. 1556–1557, 2015.
@article{Liu2015,
title = {Rational approach to understanding and preventing sports-related traumatic brain injuries},
author = {Liu, C Y and Law, M and Romano, R},
doi = {10.1016/j.wneu.2015.07.076},
year = {2015},
date = {2015-01-01},
journal = {World Neurosurgery},
volume = {84},
number = {6},
pages = {1556--1557},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gardner, A J; Iverson, G L; Quinn, T N; Makdissi, M; Levi, C R; Shultz, S R; Wright, D K; Stanwell, P
A preliminary video analysis of concussion in the National Rugby League Journal Article
In: Brain Injury, vol. 29, no. 10, pp. 1182–1185, 2015.
@article{Gardner2015b,
title = {A preliminary video analysis of concussion in the National Rugby League},
author = {Gardner, A J and Iverson, G L and Quinn, T N and Makdissi, M and Levi, C R and Shultz, S R and Wright, D K and Stanwell, P},
doi = {10.3109/02699052.2015.1034179},
year = {2015},
date = {2015-01-01},
journal = {Brain Injury},
volume = {29},
number = {10},
pages = {1182--1185},
abstract = {Primary objective: To conduct the first video analysis of concussion in the Australian National Rugby League (NRL) and describe player and injury characteristics, situational factors and time to return to play.Research design: Descriptive, observational case series.Methods and procedures: Video analysis of 20 medically diagnosed concussions for three consenting clubs during the 2013 NRL season.Main outcome and results: Most concussions (83%) occurred during a high tackle, and all injured ball carriers were hit high. Loss of consciousness was observed in 30% of cases. Common observable signs of injury included clutching of the head, balance problems or wobbly legs and a blank or vacant state. There were no post-concussive seizures. All players with loss of consciousness were removed from play. However, only half of the total sample was removed from play and one athlete who was removed returned to play in the same match. Of the players who were removed from play, the large majority returned the following week. Illegal play accounted for 25% of all concussions.Conclusions: Video analysis may be a useful method to study the incidence, mechanism and management of concussion in sports such as Rugby League. Future studies may include larger numbers to validate this preliminary data and may also investigate other levels of play and age ranges. © 2015 Taylor and Francis Group, LLC.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dessy, A M; Rasouli, J; Choudhri, T F
Second Impact Syndrome: A Rare, Devastating Consequence of Repetitive Head Injuries Journal Article
In: Neurosurgery Quarterly, vol. 25, no. 3, pp. 423–426, 2015.
@article{Dessy2015,
title = {Second Impact Syndrome: A Rare, Devastating Consequence of Repetitive Head Injuries},
author = {Dessy, A M and Rasouli, J and Choudhri, T F},
doi = {10.1097/WNQ.0000000000000085},
year = {2015},
date = {2015-01-01},
journal = {Neurosurgery Quarterly},
volume = {25},
number = {3},
pages = {423--426},
abstract = {Sports-related concussion has been viewed as a developing public health crisis in recent years. Underrecognition of concussions can lead to premature clearance for athletic participation. Second impact syndrome (SIS) represents a rare, yet devastating, potential outcome of premature return to play. SIS is a condition in which rapid brain swelling occurs as a result of a repeat head injury sustained before symptoms of a previous head injury have resolved. Within minutes of the second impact, diffuse cerebral swelling, brain herniation, and death can occur. There are \<20 documented cases of SIS in the world literature to date, and the general understanding of the syndrome is based largely on interpretation of anecdotal cases. This article reviews current understanding of the epidemiology and pathology of SIS. Given neurosurgeons' role in management of head trauma, it is essential that neurosurgeons acquire and maintain thorough knowledge of concussion diagnosis, treatment, and management. © 2014 Wolters Kluwer Health, Inc. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mayer, A R; Ling, J M; Dodd, A B; Gasparovic, C; Klimaj, S D; Meier, T B
A Longitudinal Assessment of Structural and Chemical Alterations in Mixed Martial Arts Fighters Journal Article
In: Journal of Neurotrauma, vol. 32, no. 22, pp. 1759–1767, 2015.
@article{Mayer2015b,
title = {A Longitudinal Assessment of Structural and Chemical Alterations in Mixed Martial Arts Fighters},
author = {Mayer, A R and Ling, J M and Dodd, A B and Gasparovic, C and Klimaj, S D and Meier, T B},
doi = {10.1089/neu.2014.3833},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neurotrauma},
volume = {32},
number = {22},
pages = {1759--1767},
abstract = {Growing evidence suggests that temporally proximal acute concussions and repetitive subconcussive head injuries may lead to long-term neurological deficits. However, the underlying mechanisms of injury and their relative time-scales are not well documented in human injury models. The current study therefore investigated whether biomarkers of brain chemistry (magnetic resonance [MR] spectroscopy: N-acetylaspartate [NAA], combined glutamate and glutamine [Glx], total creatine [Cre], choline compounds [Cho], and myo-inositol [mI]) and structure (cortical thickness, white matter [WM]/subcortical volume) differed between mixed martial artists (MMA; n = 13) and matched healthy controls (HC) without a history of contact sport participation (HC; n = 14). A subset of participants (MMA = 9; HC = 10) returned for follow-up visits, with MMA (n = 3) with clinician-documented acute concussions also scanned serially. As expected, MMA self-reported a higher incidence of previous concussions and significantly more cognitive symptoms during prior concussion recovery. Fighters also exhibited reduced memory and processing speed relative to controls on neuropsychological testing coupled with cortical thinning in the left posterior cingulate gyrus and right occipital cortex at baseline assessment. Over a 1-year follow-up period, MMA experienced a significant decrease in both WM volume and NAA concentration, as well as relative thinning in the left middle and superior frontal gyri. These longitudinal changes did not correlate with self-reported metrics of injury (i.e., fight diary). In contrast, HC did not exhibit significant longitudinal changes over a 4-month follow-up period (p \> 0.05). Collectively, current results provide preliminary evidence of progressive changes in brain chemistry and structure over a relatively short time period in individuals with high exposure to repetitive head hits. These findings require replication in independent samples. © Mary Ann Liebert, Inc. 2015.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Stone Jr., M E; Safadjou, S; Farber, B; Velazco, N; Man, J; Reddy, S H; Todor, R; Teperman, S
Utility of the Military Acute Concussion Evaluation as a screening tool for mild traumatic brain injury in a civilian trauma population Journal Article
In: Journal of Trauma and Acute Care Surgery, vol. 79, no. 1, pp. 147–151, 2015.
@article{StoneJr.2015,
title = {Utility of the Military Acute Concussion Evaluation as a screening tool for mild traumatic brain injury in a civilian trauma population},
author = {{Stone Jr.}, M E and Safadjou, S and Farber, B and Velazco, N and Man, J and Reddy, S H and Todor, R and Teperman, S},
doi = {10.1097/TA.0000000000000679},
year = {2015},
date = {2015-01-01},
journal = {Journal of Trauma and Acute Care Surgery},
volume = {79},
number = {1},
pages = {147--151},
abstract = {BACKGROUND: Mild traumatic brain injury (mTBI) constitutes 75% of more than 1.5 million traumatic brain injuries annually. There exists no consensus on point-of-care screening for mTBI. The Military Acute Concussion Evaluation (MACE) is a quick and easy test used by the US Army to screen for mTBI; however, its utility in civilian trauma is unclear. It has two parts: a history section and the Standardized Assessment of Concussion (SAC) score (0-30) previously validated in sports injury. As a performance improvement project, our institution sought to evaluate the MACE as a concussion screening tool that could be used by housestaff in a general civilian trauma population. METHODS: From June 2013 to May 2014, patients 18 years to 65 years old with suspected concussion were given the MACE within 72 hours of admission to our urban Level I trauma center. Patients with a positive head computed tomography were excluded. Demographic data and MACE scores were recorded in prospect. Concussion was defined as loss of consciousness and/or posttraumatic amnesia; concussed patients were compared with those nonconcussed. Sensitivity and specificity for each respective MACE score were used to plot a receiver operating characteristic (ROC) curve. An ROC curve area of 0.8 was set as the benchmark for a good screening test to distinguish concussion from nonconcussion. RESULTS: There were 84 concussions and 30 nonconcussed patients. Both groups were similar; however, the concussion group had a lower mean MACE score than the nonconcussed patients. Data analysis demonstrated the sensitivity and specificity of a range of MACE scores used to generate an ROC curve area of only 0.65. CONCLUSION: The MACE showed a lower mean score for individuals with concussion, defined by loss of consciousness and/or posttraumatic amnesia. However, the ROC curve area of 0.65 highly suggests that MACE alone would be a poor screening test for mTBI in a general civilian trauma population. LEVEL OF EVIDENCE: Diagnostic study, level II. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dretsch, M N; Kelly, M P; Coldren, R L; Parish, R V; Russell, M L
In: Journal of Neurotrauma, vol. 32, no. 16, pp. 1217–1222, 2015.
@article{Dretsch2015a,
title = {No Significant Acute and Subacute Differences between Blast and Blunt Concussions across Multiple Neurocognitive Measures and Symptoms in Deployed Soldiers},
author = {Dretsch, M N and Kelly, M P and Coldren, R L and Parish, R V and Russell, M L},
doi = {10.1089/neu.2014.3637},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neurotrauma},
volume = {32},
number = {16},
pages = {1217--1222},
abstract = {Seventy-one deployed U.S. Army soldiers who presented for concussion care due to either blast or blunt mechanisms within 72 h of injury were assessed using the Military Acute Concussion Evaluation, the Automated Neuropsychological Assessment Metrics (ANAM), traditional neuropsychological tests, and health status questionnaires. Follow-up ANAM testing was performed 10 d after initial testing (±5 d). Twenty-one soldiers were excluded: two for poor effort and 19 who had combined blast/blunt injuries. Of the remaining 50 male participants, 34 had blast injuries and 16 had blunt injuries. There were no statistically significant differences between blast injury and blunt injury participants in demographic, physical, or psychological health factors, concussive symptoms, or automated and traditional neurocognitive testing scores within 72 h post-injury. In addition, follow-up ANAM scores up to 15 d post-injury were not significantly different (available on 21 blast-injured and 13 blunt-injured subjects). Pre-injury baseline ANAM scores were compared where available, and revealed no statistically significant differences between 22 blast injury and eight blunt injury participants. These findings suggest there are no significant differences between mechanisms of injury during both the acute and subacute periods in neurobehavioral concussion sequelae while deployed in a combat environment. The current study supports the use of sports/mechanical concussion models for early concussion management in the deployed setting and exploration of variability in potential long-term outcomes. © Copyright 2015, Mary Ann Liebert, Inc.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Ellis, M J; Cordingley, D; Vis, S; Reimer, K; Leiter, J; Russell, K
Vestibulo-ocular dysfunction in pediatric sports-related concussion Journal Article
In: Journal of Neurosurgery: Pediatrics, vol. 16, no. 3, pp. 248–255, 2015.
@article{Ellis2015,
title = {Vestibulo-ocular dysfunction in pediatric sports-related concussion},
author = {Ellis, M J and Cordingley, D and Vis, S and Reimer, K and Leiter, J and Russell, K},
doi = {10.3171/2015.1.PEDS14524},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neurosurgery: Pediatrics},
volume = {16},
number = {3},
pages = {248--255},
abstract = {Object The objective of this study was 2-fold: 1) to examine the prevalence of vestibulo-ocular dysfunction (VOD) among children and adolescents with acute sports-related concussion (SRC) and postconcussion syndrome (PCS) who were referred to a multidisciplinary pediatric concussion program; and 2) to determine if VOD is associated with the development of PCS in this cohort. Methods The authors conducted a retrospective review of all patients with acute SRC (presenting 30 days or less postinjury) and PCS (3 or more symptoms for at least 1 month) referred to a multidisciplinary pediatric concussion program between September 2013 and July 2014. Initial assessment included clinical history, physical examination, and Post-Concussion Symptom Scale assessment. Patients were also assessed for VOD, which was defined as more than one subjective vestibular and oculomotor complaint (dizziness, blurred vision, and so on) and more than one objective physical examination finding (abnormal smooth pursuits, saccades, vestibulo-ocular reflex, and so on). This study was approved by the local institutional ethics review board. Results A total of 101 patients (mean age 14.2 years, SD 2.3 years; 63 male and 38 female patients) participated, including 77 (76.2%) with acute SRC and 24 (23.8%) with PCS. Twenty-two of the 77 patients (28.6%) with acute SRC and 15 of the 24 (62.5%) with PCS met the clinical criteria for VOD. The median duration of symptoms was 40 days (interquartile range [IQR] 28.5-54 days) for patients with acute SRC who had VOD compared with 21 days (IQR 13-32 days) for those without VOD (p = 0.0001). There was a statistically significant increase in the adjusted odds of developing PCS among patients with acute SRC who had VOD compared with those without VOD (adjusted OR 4.10; 95% CI 1.04-16.16). Conclusions Evidence of VOD was detected in a significant proportion of children and adolescents with acute SRC and PCS who were referred to a multidisciplinary pediatric concussion program. This clinical feature was a significant risk factor for the subsequent development of PCS in this pediatric acute SRC cohort. © AANS, 2015.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Brewster, R; Bi, W L; Smith, T R; Gormley, W B; Dunn, I F; Laws Jr., E R
The neurosurgeon as baseball fan and inventor: Walter Dandy and the batter's helmet Journal Article
In: Neurosurgical Focus, vol. 39, no. 1, 2015.
Abstract | Links | BibTeX | Tags: 19th Century, 20th Century, Baseball, Baseball helmet, brain concussion, Head Protective Devices, Head trauma, Helmet, HISTORY, human, Humans, Injuries, Innovation, Male, middle aged, neurosurgeon, Neurosurgeons, Protective gear, traumatic brain injury, Walter dandy
@article{Brewster2015,
title = {The neurosurgeon as baseball fan and inventor: Walter Dandy and the batter's helmet},
author = {Brewster, R and Bi, W L and Smith, T R and Gormley, W B and Dunn, I F and {Laws Jr.}, E R},
doi = {10.3171/2015.3.FOCUS1552},
year = {2015},
date = {2015-01-01},
journal = {Neurosurgical Focus},
volume = {39},
number = {1},
abstract = {Baseball maintains one of the highest impact injury rates in all athletics. A principal causative factor is the "beanball," referring to a pitch thrown directly at a batter's head. Frequent morbidities elicited demand for the development of protective gear development in the 20th century. In this setting, Dr. Walter Dandy was commissioned to design a "protective cap" in 1941. His invention became widely adopted by professional baseball and inspired subsequent generations of batting helmets. As a baseball aficionado since his youth, Walter Dandy identified a natural partnership between baseball and medical practice for the reduction of beaning-related brain injuries. This history further supports the unique position of neurosurgeons to leverage clinical insights, inform innovation, and expand service to society. © AANS, 2015.},
keywords = {19th Century, 20th Century, Baseball, Baseball helmet, brain concussion, Head Protective Devices, Head trauma, Helmet, HISTORY, human, Humans, Injuries, Innovation, Male, middle aged, neurosurgeon, Neurosurgeons, Protective gear, traumatic brain injury, Walter dandy},
pubstate = {published},
tppubtype = {article}
}
Lawrence, D W; Comper, P; Hutchison, M G; Sharma, B
The role of apolipoprotein E episilon ($epsilon$)-4 allele on outcome following traumatic brain injury: A systematic review Journal Article
In: Brain Injury, vol. 29, no. 9, pp. 1018–1031, 2015.
Abstract | Links | BibTeX | Tags: 80 and over, aged, allele, Alleles, Alzheimer disease, amyloid beta protein, APOE, apolipoprotein E, apolipoprotein E4, Article, athlete, brain concussion, Brain Injuries, clinical evaluation, cognition, cognitive defect, disease severity, Female, follow up, genetic association, genetic risk, genetics, GENOTYPE, Glasgow Outcome Scale, heterozygote, histopathology, homozygote, human, Humans, Incidence, injury severity, Male, Memory, nerve cell necrosis, neuropathology, Neuroprotection, outcome assessment, pediatrics, Prevalence, Prognosis, prognostic assessment, protein function, psychologic test, psychology, Recovery, scoring system, Systematic Review, tau protein, traumatic brain injury, treatment outcome, very elderly, Wechsler Intelligence Scale
@article{Lawrence2015,
title = {The role of apolipoprotein E episilon ($epsilon$)-4 allele on outcome following traumatic brain injury: A systematic review},
author = {Lawrence, D W and Comper, P and Hutchison, M G and Sharma, B},
doi = {10.3109/02699052.2015.1005131},
year = {2015},
date = {2015-01-01},
journal = {Brain Injury},
volume = {29},
number = {9},
pages = {1018--1031},
abstract = {Background: The apolipoprotein E gene (APOE) has emerged as a candidate for prognosticating traumatic brain injury (TBI) recovery, with APOE$epsilon$4 identified as a susceptibility marker for poor outcome, despite large discrepancy in its reported influence post-TBI.Methods: A systematic review was conducted, including all primary articles investigating the role of APOE$epsilon$4 on TBI outcome. A total of 65 studies were included, including 24 predominantly investigating mild (mTBI), seven moderate (modTBI) and 33 severe (sTBI); severity was not reported in one study.Results: In mTBI studies, the association between APOE$epsilon$4 and post-TBI outcome was concluded as non-contributory in 14 studies (58.3%), hazardous in nine (37.5%) and protective in one (4.2%). In sTBI studies, the role of APOE$epsilon$4 was hazardous in 21 (63.6%), non-contributory in nine (27.3%) and protective in three (9.1%). Of the seven studies investigating dementia outcomes, four observed a hazardous association with APOE$epsilon$4, while three reported no association. Six studies examined Alzheimers dementia pathology, of which three reported a hazardous influence of APOE$epsilon$4.Conclusions: The influence of APOE$epsilon$4 on neuropsychological testing, functional outcome and in paediatric populations was incongruous. This review supports the majority of research indicating APOE$epsilon$4 adversely influences recovery following TBI, particularly with respect to dementia-related outcomes and outcomes following sTBI. © 2015 Taylor \& Francis Group, LLC.},
keywords = {80 and over, aged, allele, Alleles, Alzheimer disease, amyloid beta protein, APOE, apolipoprotein E, apolipoprotein E4, Article, athlete, brain concussion, Brain Injuries, clinical evaluation, cognition, cognitive defect, disease severity, Female, follow up, genetic association, genetic risk, genetics, GENOTYPE, Glasgow Outcome Scale, heterozygote, histopathology, homozygote, human, Humans, Incidence, injury severity, Male, Memory, nerve cell necrosis, neuropathology, Neuroprotection, outcome assessment, pediatrics, Prevalence, Prognosis, prognostic assessment, protein function, psychologic test, psychology, Recovery, scoring system, Systematic Review, tau protein, traumatic brain injury, treatment outcome, very elderly, Wechsler Intelligence Scale},
pubstate = {published},
tppubtype = {article}
}
Bowman, T G; Breedlove, K M; Breedlove, E L; Dodge, T M; Nauman, E A
Impact attenuation properties of new and used lacrosse helmets Journal Article
In: Journal of Biomechanics, vol. 48, no. 14, pp. 3782–3787, 2015.
Abstract | Links | BibTeX | Tags: Accident prevention, Article, Athletic Injuries, attenuation, brain concussion, Cracks, Drop test, Drops, Equipment Design, Gadd Severity Index, head impact, Head Protective Devices, Helmet, Helmet evaluation, human, Humans, Injuries, lacrosse helmet, Materials testing, mechanical stress, priority journal, protective equipment, racquet sport, Racquet Sports, recertification, rigidity, Safety devices, Severity index, Sporting goods, Sports Equipment, standards, stress strain relationship, velocity
@article{Bowman2015,
title = {Impact attenuation properties of new and used lacrosse helmets},
author = {Bowman, T G and Breedlove, K M and Breedlove, E L and Dodge, T M and Nauman, E A},
doi = {10.1016/j.jbiomech.2015.08.026},
year = {2015},
date = {2015-01-01},
journal = {Journal of Biomechanics},
volume = {48},
number = {14},
pages = {3782--3787},
abstract = {The National Operating Committee on Standards for Athletic Equipment (NOCSAE) has developed impact attenuation thresholds that protective helmets worn in sport must meet to be commercially available in an attempt to prevent injury. It remains unknown how normal helmet use in athletic activity alters the force attenuation ability of lacrosse helmets. We tested 3 new and 3 randomly selected used helmets from 2 popular lacrosse models (Cascade Pro7, Cascade CPXR). All used helmets had been worn for 3 collegiate seasons prior to testing and had never been refurbished. Helmets were drop-tested using 3 prescribed impact velocities at 6 locations according to the NOCSAE lacrosse helmet standard, and we compared the Gadd Severity Index (GSI) scores between new and used helmets using a repeated measure ANOVA with location as the repeated variable and data separated by impact velocity. All 12 helmets passed the NOCSAE GSI threshold for all testing conditions; however 1 used helmet shell cracked resulting in a failed test. We found a significant main effect for helmet age at the low (F5},
keywords = {Accident prevention, Article, Athletic Injuries, attenuation, brain concussion, Cracks, Drop test, Drops, Equipment Design, Gadd Severity Index, head impact, Head Protective Devices, Helmet, Helmet evaluation, human, Humans, Injuries, lacrosse helmet, Materials testing, mechanical stress, priority journal, protective equipment, racquet sport, Racquet Sports, recertification, rigidity, Safety devices, Severity index, Sporting goods, Sports Equipment, standards, stress strain relationship, velocity},
pubstate = {published},
tppubtype = {article}
}
De Matteo, C; Volterman, K A; Breithaupt, P G; Claridge, E A; Adamich, J; Timmons, B W
Exertion testing in youth with mild traumatic brain injury/concussion Journal Article
In: Medicine & Science in Sports & Exercise, vol. 47, no. 11, pp. 2283–2290, 2015.
Abstract | Links | BibTeX | Tags: Adolescent, adolescents, brain concussion, Child, children, Cross-Sectional Studies, cross-sectional study, exercise, exercise test, exercise tolerance, Female, head injury, human, Humans, Male, Pathophysiology, Physical Exertion, Post-Concussion Syndrome, postconcussion syndrome, Return to Play, return to sport, time factor, Time Factors
@article{DeMatteo2015,
title = {Exertion testing in youth with mild traumatic brain injury/concussion},
author = {{De Matteo}, C and Volterman, K A and Breithaupt, P G and Claridge, E A and Adamich, J and Timmons, B W},
doi = {10.1249/MSS.0000000000000682},
year = {2015},
date = {2015-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {47},
number = {11},
pages = {2283--2290},
abstract = {Purpose The decision regarding return to activity (RTA) after mild traumatic brain injuries/concussion is one of the most difficult and controversial areas in concussion management, particularly for youth. This study investigated how youth with postconcussion syndrome (PCS) are affected by exertion and whether standardized exertion testing using the McMaster All-Out Progressive Continuous Cycling Test can contribute to clinical decision making for safe RTA. Methods Fifty-four youth (8.5-18.3 yr) with a previously confirmed concussion participated in the study. Each participant performed exertion testing on a cycle ergometer and completed a Postconcussion Symptom scale at the following time points: before exertion (baseline), 5 and 30 min, and 24 h after exertion. A modified Postconcussion Symptom scale was administered at 2-min intervals during exertion. Results Participants had a mean ± SD symptom duration of 6.3 ± 6.9 months after the most recent concussive injury, with a median of 4.1 months (range, 0.7-35 months). Sixty-three percent of participants had symptoms during exertion testing. Symptom profile (number and severity) significantly affected perception of exertion at 50% peak mechanical power. During acute assessment of symptoms (30-min after exertion), headache (P = 0.39), nausea (P = 0.63), and dizziness (P = 0.35) did not change. However, both the number and severity of symptoms significantly improved over 24 h, with 56.8% of youth showing improvements. The time from the most recent injury had a significant effect on the symptom score at baseline, 30 min after exertion, and 24 h after exertion. Conclusions Exertion testing has an important role in the evaluation of symptoms and readiness to RTA, particularly in youth who are slow to recover. Overall, controlled exertion seemed to lesson symptoms for most youth. © 2015 by the American College of Sports Medicine.},
keywords = {Adolescent, adolescents, brain concussion, Child, children, Cross-Sectional Studies, cross-sectional study, exercise, exercise test, exercise tolerance, Female, head injury, human, Humans, Male, Pathophysiology, Physical Exertion, Post-Concussion Syndrome, postconcussion syndrome, Return to Play, return to sport, time factor, Time Factors},
pubstate = {published},
tppubtype = {article}
}
Dematteo, Carol; Volterman, Kimberly A; Breithaupt, Peter G; Claridge, Everett A; Adamich, John; Timmons, Brian W
Exertion Testing in Youth with Mild Traumatic Brain Injury/Concussion Journal Article
In: Medicine & Science in Sports & Exercise, vol. 47, no. 11, pp. 2283–2290, 2015, ISBN: 01959131.
Abstract | BibTeX | Tags: *BRAIN -- Concussion, *BRAIN -- Wounds & injuries, *EXERCISE, *EXERCISE tests, *POSTCONCUSSION syndrome, *SPORTS participation, ADOLESCENCE, adolescents, brain concussion, children, DATA analysis, DATA analysis -- Software, DECISION making in clinical medicine, DESCRIPTIVE statistics, head injury, MULTIPLE regression analysis, ONE-way analysis of variance, postconcussion syndrome, RESEARCH -- Finance, Return to Play, SAMPLING (Statistics), STATISTICS
@article{Dematteo2015b,
title = {Exertion Testing in Youth with Mild Traumatic Brain Injury/Concussion},
author = {Dematteo, Carol and Volterman, Kimberly A and Breithaupt, Peter G and Claridge, Everett A and Adamich, John and Timmons, Brian W},
isbn = {01959131},
year = {2015},
date = {2015-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {47},
number = {11},
pages = {2283--2290},
abstract = {Purpose: The decision regarding return to activity (RTA) after mild traumatic brain injuries/concussion is one of the most difficult and controversial areas in concussion management, particularly for youth. This study investigated how youth with postconcussion syndrome (PCS) are affected by exertion and whether standardized exertion testing using the McMaster All-Out Progressive Continuous Cycling Test can contribute to clinical decision making for safe RTA. Methods: Fifty-four youth (8.5-18.3 yr) with a previously confirmed concussion participated in the study. Each participant performed exertion testing on a cycle ergometer and completed a Postconcussion Symptom scale at the following time points: before exertion (baseline), 5 and 30 min, and 24 h after exertion. A modified Postconcussion Symptom scale was administered at 2-min intervals during exertion. Results: Participants had a mean T SD symptom duration of 6.3 T 6.9 months after the most recent concussive injury, with a median of 4.1 months (range, 0.7-35 months). Sixty-three percent of participants had symptoms during exertion testing. Symptom profile (number and severity) significantly affected perception of exertion at 50% peak mechanical power. During acute assessment of symptoms (30-min after exertion), headache (P = 0.39), nausea (P = 0.63), and dizziness (P = 0.35) did not change. However, both the number and severity of symptoms significantly improved over 24 h, with 56.8% of youth showing improvements. The time from the most recent injury had a significant effect on the symptom score at baseline, 30 min after exertion, and 24 h after exertion. Conclusions: Exertion testing has an important role in the evaluation of symptoms and readiness to RTA, particularly in youth who are slow to recover. Overall, controlled exertion seemed to lesson symptoms for most youth. ABSTRACT FROM AUTHOR},
keywords = {*BRAIN -- Concussion, *BRAIN -- Wounds \& injuries, *EXERCISE, *EXERCISE tests, *POSTCONCUSSION syndrome, *SPORTS participation, ADOLESCENCE, adolescents, brain concussion, children, DATA analysis, DATA analysis -- Software, DECISION making in clinical medicine, DESCRIPTIVE statistics, head injury, MULTIPLE regression analysis, ONE-way analysis of variance, postconcussion syndrome, RESEARCH -- Finance, Return to Play, SAMPLING (Statistics), STATISTICS},
pubstate = {published},
tppubtype = {article}
}
Register-Mihalik, J K; De Maio, V J; Tibbo-Valeriote, H L; Wooten, J D
Characteristics of pediatric and adolescent concussion clinic patients with postconcussion amnesia Journal Article
In: Clinical Journal of Sport Medicine, vol. 25, no. 6, pp. 502–508, 2015.
Abstract | BibTeX | Tags: Adolescent, adult, amnesia, anamnesis, Article, brain concussion, Child, complication, Concussion, Concussive injury, Cross-Sectional Studies, cross-sectional study, Demography, disease severity, emergency ward, ethnology, Female, head injury, human, Humans, major clinical study, Male, MEDICAL history taking, Memory, ODDS ratio, outcome assessment, postconcussion symptoms, priority journal, race, Retrospective Studies, retrospective study, Risk, risk factor, Risk Factors, unconsciousness
@article{Register-Mihalik2015,
title = {Characteristics of pediatric and adolescent concussion clinic patients with postconcussion amnesia},
author = {Register-Mihalik, J K and {De Maio}, V J and Tibbo-Valeriote, H L and Wooten, J D},
year = {2015},
date = {2015-01-01},
journal = {Clinical Journal of Sport Medicine},
volume = {25},
number = {6},
pages = {502--508},
abstract = {Objective: The current study examines the demographics, injury characteristics, and outcomes associated with the presence of postconcussion amnesia in young concussion clinic patients. Design: Cross-sectional, retrospective clinical cohort. Setting: Concussion services clinic. Patients: Pediatric and adolescent concussion services program patients, presenting within 10 days postinjury, aged 10-18 years, with the goal of returning to sport (n = 245). Assessment of Risk Factors: Age, gender, race, head trauma history, injury mechanism, loss of consciousness (LOC), injuryrelated visit to an emergency department, cognitive and balance scores, symptoms, and management recommendations. Main Outcome Measures: Univariate and multivariate analyses determined adjusted odds ratios for reported presence of any postconcussion amnesia (anterograde or retrograde). Results: Factors associated with amnesia (univariate, P \< 0.10) and included in the multivariate model were race, head trauma history, mechanism of injury, LOC, injury-related visit to an emergency department, management recommendations and time of injury and initial visit symptom severity. Age and gender were also included in the model due to biological significance. Of the 245 patients, 181 had data for all model variables. Of the 181 patients, 58 reported amnesia. History of head trauma [odds ratio (OR), 2.7; 95% confidence interval (CI), 1.3-5.7]; time of injury (TOI) symptom severity \>75th percentile (OR, 2.6; 95% CI, 1.2-5.3) and LOC (OR, 2.2; 95% CI, 1.1-4.6) were found to have significant and independent relationships with amnesia in the multivariate model. Conclusions: This study illustrates that patients presenting with postconcussion amnesia are more likely to have a history of head trauma, LOC, and greater symptom severity. Future research is needed to better understand amnesia following concussion. Clinical Relevance: Amnesia presence, previous head trauma, LOC, and increased symptom severity may aid in identifying patients with a greater initial injury burden who warrant closer observation and more conservative management. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.},
keywords = {Adolescent, adult, amnesia, anamnesis, Article, brain concussion, Child, complication, Concussion, Concussive injury, Cross-Sectional Studies, cross-sectional study, Demography, disease severity, emergency ward, ethnology, Female, head injury, human, Humans, major clinical study, Male, MEDICAL history taking, Memory, ODDS ratio, outcome assessment, postconcussion symptoms, priority journal, race, Retrospective Studies, retrospective study, Risk, risk factor, Risk Factors, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Merritt, V C; Meyer, J E; Arnett, P A
A novel approach to classifying postconcussion symptoms: The application of a new framework to the Post-Concussion Symptom Scale Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 37, no. 7, pp. 764–775, 2015.
Abstract | Links | BibTeX | Tags: Adolescent, Athletic Injuries, brain concussion, CLASSIFICATION, collegiate athletes, Female, human, Humans, Male, neuropsychological test, Neuropsychological Tests, Post-Concussion Syndrome, postconcussion symptoms, self report, SEVERITY of illness index, Sports-related concussion, symptom assessment, Young Adult
@article{Merritt2015b,
title = {A novel approach to classifying postconcussion symptoms: The application of a new framework to the Post-Concussion Symptom Scale},
author = {Merritt, V C and Meyer, J E and Arnett, P A},
doi = {10.1080/13803395.2015.1060950},
year = {2015},
date = {2015-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {37},
number = {7},
pages = {764--775},
abstract = {Introduction: Self-report measures such as the Post-Concussion Symptom Scale (PCSS) are frequently used during baseline and postconcussion testing to evaluate athletes symptom profiles. However, the common approach of evaluating the total symptom score and/or symptom clusters may not allow for a complete understanding of the nature of athletes symptom reporting patterns. The primary objective of this study was to apply three "global indices of distress" variables, derived from the Symptom Checklist-90-Revised (SCL-90-R) framework, to the PCSS at baseline and postconcussion. We aimed to evaluate the utility of these symptom indices in relation to four PCSS symptom clusters and the total PCSS symptom score. Method: Participants included college athletes evaluated at baseline (N = 846) and postconcussion (N = 86). Athletes underwent neuropsychological testing at both time points, including completion of the PCSS and a paper/pencil and computerized test battery. Eight symptom indices were derived from the PCSS, and a postconcussion neurocognitive composite score was calculated. Results: Results showed that there were significant mean increases from baseline to postconcussion on four of the eight symptom indices evaluated. Furthermore, a significant proportion of athletes showed no change from baseline to postconcussion when evaluating the total symptom score, but showed at least a one standard deviation increase in symptom reporting from baseline to postconcussion when evaluating at least one other symptom index (i.e., a global index of distress or symptom cluster). Finally, the three global indices of distress variables, two of the four symptom clusters, and the total symptom score significantly predicted a postconcussion neurocognitive composite score, such that greater postconcussion symptoms were associated with lower postconcussion neurocognitive performance. Conclusions: These findings suggest that, in addition to evaluating the postconcussion total symptom score, there may be value in examining more specific symptom indices such as the global indices of distress variables and symptom clusters. © 2015 Taylor \& Francis.},
keywords = {Adolescent, Athletic Injuries, brain concussion, CLASSIFICATION, collegiate athletes, Female, human, Humans, Male, neuropsychological test, Neuropsychological Tests, Post-Concussion Syndrome, postconcussion symptoms, self report, SEVERITY of illness index, Sports-related concussion, symptom assessment, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Hendricks, S; O’Connor, S; Lambert, M; Brown, J; Burger, N; Fie, S M; Readhead, C; Viljoen, W
Contact technique and concussions in the South African under-18 Coca-Cola craven week rugby tournament Journal Article
In: European Journal of Sport Science, vol. 15, no. 6, pp. 557–564, 2015.
Abstract | Links | BibTeX | Tags: Athletic Injuries, brain concussion, Concussion, football, human, Humans, Injury and prevention, measurement, PHYSIOLOGY, Skill, team sport, videorecording, Videotape Recording
@article{Hendricks2015,
title = {Contact technique and concussions in the South African under-18 Coca-Cola craven week rugby tournament},
author = {Hendricks, S and O’Connor, S and Lambert, M and Brown, J and Burger, N and Fie, S M and Readhead, C and Viljoen, W},
doi = {10.1080/17461391.2015.1046192},
year = {2015},
date = {2015-01-01},
journal = {European Journal of Sport Science},
volume = {15},
number = {6},
pages = {557--564},
abstract = {In rugby union, understanding the techniques and events leading to concussions is important because of the nature of the injury and the severity and potential long-term consequences, particularly in junior players. Proper contact technique is a prerequisite for successful participation in rugby and is a major factor associated with injury. However, the execution of proper contact technique and its relationship to injury has yet to be studied in matches. Therefore, the aim of this study was to compare contact techniques leading to concussion with a representative sample of similarly matched non-injury (NI) contact events. Injury surveillance was conducted at the 2011-2013 under-18 Craven Week Rugby tournaments. Video footage of 10 concussive events (5 tackle, 4 ruck and 1 aerial collision) and 83 NI events were identified (19 tackle, 61 ruck and 3 aerial collisions). Thereafter, each phase of play was analysed using standardised technical proficiency criteria. Overall score for ruck proficiency in concussive events was 5.67 (out of a total of 15) vs. 6.98 for NI events (n = 54) (effect size = 0.52, small). Overall average score for tackler proficiency was 7.25 (n = 4) and 6.67 (n = 15) for injury and NI tackles, respectively (out of 16) (effect size = 0.19, trivial). This is the first study to compare concussion injury contact technique to a player-matched sample of NI contact techniques. Certain individual technical criteria had an effect towards an NI outcome, and others had an effect towards a concussive event, highlighting that failure to execute certain techniques may substantially increase the opportunity for concussion. © 2015 European College of Sport Science.},
keywords = {Athletic Injuries, brain concussion, Concussion, football, human, Humans, Injury and prevention, measurement, PHYSIOLOGY, Skill, team sport, videorecording, Videotape Recording},
pubstate = {published},
tppubtype = {article}
}
Marinides, Z; Galetta, K M; Andrews, C N; Wilson, J A; Herman, D C; Robinson, C D; Smith, M S; Bentley, B C; Galetta, S L; Balcer, L J; Clugston, J R
Vision testing is additive to the sideline assessment of sports-related concussion Journal Article
In: Neurology: Clinical Practice, vol. 5, no. 1, pp. 25–34, 2015.
Abstract | Links | BibTeX | Tags: Article, athlete, Balance Error Scoring System, brain concussion, clinical assessment, Female, football, human, King Devick Test, major clinical study, Male, priority journal, Soccer, sport injury, Standardized Assessment of Concussion, vision test
@article{Marinides2015,
title = {Vision testing is additive to the sideline assessment of sports-related concussion},
author = {Marinides, Z and Galetta, K M and Andrews, C N and Wilson, J A and Herman, D C and Robinson, C D and Smith, M S and Bentley, B C and Galetta, S L and Balcer, L J and Clugston, J R},
doi = {10.1212/CPJ.0000000000000060},
year = {2015},
date = {2015-01-01},
journal = {Neurology: Clinical Practice},
volume = {5},
number = {1},
pages = {25--34},
abstract = {We examined the King-Devick (K-D) test, a vision-based test of rapid number naming, as a complement to components of the Sport Concussion Assessment Tool, 3rd edition (SCAT3) for diagnosis of concussion. Baseline and postconcussion data for the University of Florida men's football, women's soccer, and women's lacrosse teams were collected, including the K-D test, Standardized Assessment of Concussion (SAC), and Balance Error Scoring System (BESS). Among 30 athletes with first concussion during their athletic season (n 5 217 total), differences from baseline to postinjury showed worsening of K-D time scores in 79%, while SAC showed a ≥2- point worsening in 52%. Combining K-D and SAC captured abnormalities in 89%; adding the BESS identified 100% of concussions. Adding a vision-based test may enhance the detection of athletes with concussion. © 2015 American Academy of Neurology.},
keywords = {Article, athlete, Balance Error Scoring System, brain concussion, clinical assessment, Female, football, human, King Devick Test, major clinical study, Male, priority journal, Soccer, sport injury, Standardized Assessment of Concussion, vision test},
pubstate = {published},
tppubtype = {article}
}
Shumko, Dr John; Toto, Diana
Education on all aspects of a concussion Journal Article
In: Exceptional Parent, vol. 45, no. 8, pp. 36–38, 2015, ISBN: 0046-9157.
BibTeX | Tags: Attitude to Health, brain concussion, Brain Concussion -- Diagnosis, Brain Concussion -- Symptoms, Brain Concussion -- Therapy, Sports Re-Entry
@article{Shumko2015,
title = {Education on all aspects of a concussion},
author = {Shumko, Dr John and Toto, Diana},
isbn = {0046-9157},
year = {2015},
date = {2015-01-01},
journal = {Exceptional Parent},
volume = {45},
number = {8},
pages = {36--38},
keywords = {Attitude to Health, brain concussion, Brain Concussion -- Diagnosis, Brain Concussion -- Symptoms, Brain Concussion -- Therapy, Sports Re-Entry},
pubstate = {published},
tppubtype = {article}
}
McGinley, A D; Master, C L; Zonfrillo, M R
Sports-Related Head Injuries in Adolescents: A Comprehensive Update Journal Article
In: Adolescent Medicine, vol. 26, no. 3, pp. 491–506, 2015.
BibTeX | Tags: Adolescent, Athletic Injuries, brain concussion, Brain Injuries, Brain Injury, Chronic, CONVALESCENCE, human, Humans, injury scale, Recovery of Function, sport injury, Trauma Severity Indices
@article{McGinley2015,
title = {Sports-Related Head Injuries in Adolescents: A Comprehensive Update},
author = {McGinley, A D and Master, C L and Zonfrillo, M R},
year = {2015},
date = {2015-01-01},
journal = {Adolescent Medicine},
volume = {26},
number = {3},
pages = {491--506},
keywords = {Adolescent, Athletic Injuries, brain concussion, Brain Injuries, Brain Injury, Chronic, CONVALESCENCE, human, Humans, injury scale, Recovery of Function, sport injury, Trauma Severity Indices},
pubstate = {published},
tppubtype = {article}
}
Antonius, D; Mathew, N; Picano, J; Hinds, A; Cogswell, A; Olympia, J; Brooks, T; Di Giacomo, M; Baker, J; Willer, B; Leddy, J
In: Journal of Neuropsychiatry and Clinical Neurosciences, vol. 26, no. 4, pp. 313–322, 2014.
Abstract | Links | BibTeX | Tags: Aggression, anxiety disorder, apathy, Article, behavior change, behavior disorder, brain concussion, buspirone, Chronic traumatic encephalopathy, Chronic Traumatic Encephalopathy beta adrenergic r, cingulate gyrus, degenerative disease, depression, euphoria, head injury, human, hypersexuality, impulse control disorder, mental disease, mental instability, mood change, nerve degeneration, neurofibrillary tangle, olanzapine, parahippocampal gyrus, personality disorder, postconcussion syndrome, posttraumatic stress disorder, priority journal, serotonin uptake inhibitor, sexual behavior, suicidal behavior, traumatic brain injury
@article{Antonius2014,
title = {Behavioral health symptoms associated with chronic traumatic encephalopathy: A critical review of the literature and recommendations for treatment and research},
author = {Antonius, D and Mathew, N and Picano, J and Hinds, A and Cogswell, A and Olympia, J and Brooks, T and {Di Giacomo}, M and Baker, J and Willer, B and Leddy, J},
url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84920996232\&partnerID=40\&md5=cb8a1deab38101900f8d7a8ac0b7a80c},
year = {2014},
date = {2014-01-01},
journal = {Journal of Neuropsychiatry and Clinical Neurosciences},
volume = {26},
number = {4},
pages = {313--322},
abstract = {Chronic traumatic encephalopathy (CTE) is a neurodegenerative syndrome that has been linked to serious psychiatric symptoms, including depression, aggression, and suicidal behavior. This review critically examines the extant research on the behavioral manifestations of CTE and concludes that the paucity of longitudinal prospective studies on CTE, combined with a lack of research-accepted diagnostic criteria for identifying individuals who are considered at risk for CTE, makes it difficult to reliably establish a causal relationship between CTE and the onset of behavioral health problems. Selection and reporting bias and inconsistency in data collection methods are other concerns. To advance the field, there is a critical need for more empirical research on the behavioral manifestations of CTE. Recommendations and intervention models are also discussed. © 2014 American Psychiatric Association.},
keywords = {Aggression, anxiety disorder, apathy, Article, behavior change, behavior disorder, brain concussion, buspirone, Chronic traumatic encephalopathy, Chronic Traumatic Encephalopathy beta adrenergic r, cingulate gyrus, degenerative disease, depression, euphoria, head injury, human, hypersexuality, impulse control disorder, mental disease, mental instability, mood change, nerve degeneration, neurofibrillary tangle, olanzapine, parahippocampal gyrus, personality disorder, postconcussion syndrome, posttraumatic stress disorder, priority journal, serotonin uptake inhibitor, sexual behavior, suicidal behavior, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Miyashita, Theresa L; Diakogeorgiou, Eleni; Hellstrom, Brian; Kuchwara, Nick; Tafoya, Erica; Lori, Young
High School Athletes' Perceptions of Concussion Journal Article
In: Orthopaedic Journal of Sports Medicine, pp. 1–5, 2014.
Links | BibTeX | Tags: ADOLESCENCE, ANALYSIS of variance, Athletes, Athletic, Athletic Training, attitude, brain concussion, Coaches, Cross Sectional Studies, Data Analysis Software, DESCRIPTIVE statistics, Female, Head Injuries, health education, Health Knowledge, high school, human, Male, Random Sample, T-Tests
@article{Miyashita2014,
title = {High School Athletes' Perceptions of Concussion},
author = {Miyashita, Theresa L and Diakogeorgiou, Eleni and Hellstrom, Brian and Kuchwara, Nick and Tafoya, Erica and Lori, Young},
doi = {10.1177/2325967114554549},
year = {2014},
date = {2014-01-01},
journal = {Orthopaedic Journal of Sports Medicine},
pages = {1--5},
publisher = {Sage Publications Inc.},
address = {Thousand Oaks, California},
keywords = {ADOLESCENCE, ANALYSIS of variance, Athletes, Athletic, Athletic Training, attitude, brain concussion, Coaches, Cross Sectional Studies, Data Analysis Software, DESCRIPTIVE statistics, Female, Head Injuries, health education, Health Knowledge, high school, human, Male, Random Sample, T-Tests},
pubstate = {published},
tppubtype = {article}
}
Anonymous,
SCAT3 Journal Article
In: British Journal of Sports Medicine, vol. 47, no. 5, pp. 259, 2013, ISBN: 1473-0480.
BibTeX | Tags: Assessment/Testing article, ataxia, body equilibrium, brain concussion, cognitive defect, emergency treatment, human, injury scale, memory disorder, METHODOLOGY, neurologic examination, neuropsychological test, Physical Examination, questionnaire, sport injury, unconsciousness
@article{Anonymous2013b,
title = {SCAT3},
author = {Anonymous},
isbn = {1473-0480},
year = {2013},
date = {2013-01-01},
journal = {British Journal of Sports Medicine},
volume = {47},
number = {5},
pages = {259},
keywords = {Assessment/Testing article, ataxia, body equilibrium, brain concussion, cognitive defect, emergency treatment, human, injury scale, memory disorder, METHODOLOGY, neurologic examination, neuropsychological test, Physical Examination, questionnaire, sport injury, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Apps, Jennifer Niskala
Review of Ahead of the game: The parent’s guide to youth sports concussion Journal Article
In: Archives of Clinical Neuropsychology, vol. 28, no. 8, pp. 867–868, 2013, ISBN: 0887-6177 1873-5843.
Abstract | Links | BibTeX | Tags: 2013, At Risk Populations, Athletes, brain concussion, health education, parent guide, Parents, sport concussion, Sports, youth athletics
@article{Apps2013,
title = {Review of Ahead of the game: The parent’s guide to youth sports concussion},
author = {Apps, Jennifer Niskala},
doi = {10.1093/arclin/act059},
isbn = {0887-6177
1873-5843},
year = {2013},
date = {2013-01-01},
journal = {Archives of Clinical Neuropsychology},
volume = {28},
number = {8},
pages = {867--868},
publisher = {Oxford University Press},
address = {United Kingdom},
abstract = {Reviews the book, Ahead of the Game: The Parent's Guide to Youth Sports Concussion by Rosemarie Scolaro Moser (2012). This book is a strong addition to the limited arsenal of useful references to help guide parents through the complex maze of information about concussion in youths. The author presents this text in an easily navigable format, with user-friendly titles and terms. While the content of the book may be intimidating for many parents, the format and writing style will not be overwhelming. Additionally, each chapter provides a review at the end, as well as useful tips, facts, and tables throughout. Parents in the midst of trying to educate themselves about this injury, preferably before they are faced with these issues, would likely be able to access individual components of the book as needed. This resource should be useful for parents and the public, as well as clinical neuropsychologists as a possible reference point for parents, community groups, and patient populations. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, At Risk Populations, Athletes, brain concussion, health education, parent guide, Parents, sport concussion, Sports, youth athletics},
pubstate = {published},
tppubtype = {article}
}
Anonymous,
Pocket CRT Journal Article
In: British Journal of Sports Medicine, vol. 47, no. 5, pp. 267, 2013, ISBN: 1473-0480.
BibTeX | Tags: ambulatory care, Article, Assessment/Testing, brain concussion, human, injury scale, memory disorder, sport injury
@article{Anonymous2013a,
title = {Pocket CRT},
author = {Anonymous},
isbn = {1473-0480},
year = {2013},
date = {2013-01-01},
journal = {British Journal of Sports Medicine},
volume = {47},
number = {5},
pages = {267},
keywords = {ambulatory care, Article, Assessment/Testing, brain concussion, human, injury scale, memory disorder, sport injury},
pubstate = {published},
tppubtype = {article}
}
Vagnozzi, Roberto; Signoretti, Stefano; Cristofori, Luciano; Alessandrini, Franco; Floris, Roberto; Isgrò, Eugenio; Ria, Antonio; Marziali, Simone; Zoccatelli, Giada; Tavazzi, Barbara; Del Bolgia, Franco; Sorge, Roberto; Broglio, Steven P; McIntosh, Tracy K; Lazzarino, Giuseppe
Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients: Corrigendum Journal Article
In: Brain: A Journal of Neurology, vol. 136, no. 11, pp. e262–e262, 2013, ISBN: 0006-8950 1460-2156.
Abstract | BibTeX | Tags: 2013, Athletes, brain concussion, BRAIN damage, Concussion, Magnetic Resonance Spectroscopy, metabolic brain damage, mild traumatic brain injury, NEUROCHEMISTRY, Recovery, Recovery (Disorders), Spectroscopy, traumatic brain injury
@article{Vagnozzi2013a,
title = {Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients: Corrigendum},
author = {Vagnozzi, Roberto and Signoretti, Stefano and Cristofori, Luciano and Alessandrini, Franco and Floris, Roberto and Isgr\`{o}, Eugenio and Ria, Antonio and Marziali, Simone and Zoccatelli, Giada and Tavazzi, Barbara and {Del Bolgia}, Franco and Sorge, Roberto and Broglio, Steven P and McIntosh, Tracy K and Lazzarino, Giuseppe},
isbn = {0006-8950
1460-2156},
year = {2013},
date = {2013-01-01},
journal = {Brain: A Journal of Neurology},
volume = {136},
number = {11},
pages = {e262--e262},
abstract = {Reports an error in 'Assessment of metabolic brain damage and recovery following mild traumatic brain injury: A multicentre, proton magnetic resonance spectroscopic study in concussed patients' by Roberto Vagnozzi, Stefano Signoretti, Luciano Cristofori, Franco Alessandrini, Roberto Floris, Eugenio Isgr\`{o}, Antonio Ria, Simone Marziale, Giada Zoccatelli, Barbara Tavazzi, Franco Del Bolgia, Roberto Sorge, Steven P. Broglio, Tracy K. McIntosh and Giuseppe Lazzarino (Brain: A Journal of Neurology, 2010[Nov], Vol 133[11], 3232-3242). In the original article, the eighth author’s surname was incorrectly given as ‘Marziale’. The corrected surname of the eighth author is present in the erratum. (The following abstract of the original article appeared in record [rid]2010-23062-009[/rid]). Concussive head injury opens a temporary window of brain vulnerability due to the impairment of cellular energetic metabolism. As experimentally demonstrated, a second mild injury occurring during this period can lead to severe brain damage, a condition clinically described as the second impact syndrome. To corroborate the validity of proton magnetic resonance spectroscopy in monitoring cerebral metabolic changes following mild traumatic brain injury, apart from the magnetic field strength (1.5 or 3.0 T) and mode of acquisition, we undertook a multicentre prospective study in which a cohort of 40 athletes suffering from concussion and a group of 30 control healthy subjects were admitted. Athletes (aged 16\textendash35 years) were recruited and examined at three different institutions between September 2007 and June 2009. They underwent assessment of brain metabolism at 3, 15, 22 and 30 days post-injury through proton magnetic resonance spectroscopy for the determination of N-acetylaspartate, creatine and choline-containing compounds. Values of these representative brain metabolites were compared with those observed in the group of non-injured controls. Comparison of spectroscopic data, obtained in controls using different field strength and/or mode of acquisition, did not show any difference in the brain metabolite ratios. Athletes with concussion exhibited the most significant alteration of metabolite ratios at Day 3 post-injury (N-acetylaspartate/creatine: −17.6%, N-acetylaspartate/choline: −21.4%; P \< 0.001 with respect to controls). On average, metabolic disturbance gradually recovered, initially in a slow fashion and, following Day 15, more rapidly. At 30 days post-injury, all athletes showed complete recovery, having metabolite ratios returned to values detected in controls. Athletes self-declared symptom clearance between 3 and 15 days after concussion. Results indicate that N-acetylaspartate determination by proton magnetic resonance spectroscopy represents a non-invasive tool to accurately measure changes in cerebral energy metabolism occurring in mild traumatic brain injury. In particular, this metabolic evaluation may significantly improve, along with other clinical assessments, the management of athletes suffering from concussion. Further studies to verify the effects of a second concussive event occurring at different time points of the recovery curve of brain metabolism are needed. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, Athletes, brain concussion, BRAIN damage, Concussion, Magnetic Resonance Spectroscopy, metabolic brain damage, mild traumatic brain injury, NEUROCHEMISTRY, Recovery, Recovery (Disorders), Spectroscopy, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Duhaime, A C
Response Journal Article
In: Journal of Neurosurgery, vol. 117, no. 6, pp. 1090–1091, 2012, ISBN: 0022-3085 1933-0693.
BibTeX | Tags: Accident prevention, Assessment & Testing, athlete, Biomechanics, brain concussion, Equipment, headache, Helmets, human, Neck pain, neurosurgery, Note, Post-Concussion, priority journal, sport injury, surgeon, symptom, Syndrome, traumatic brain injury, unconsciousness
@article{Duhaime2012,
title = {Response},
author = {Duhaime, A C},
isbn = {0022-3085
1933-0693},
year = {2012},
date = {2012-01-01},
journal = {Journal of Neurosurgery},
volume = {117},
number = {6},
pages = {1090--1091},
keywords = {Accident prevention, Assessment \& Testing, athlete, Biomechanics, brain concussion, Equipment, headache, Helmets, human, Neck pain, neurosurgery, Note, Post-Concussion, priority journal, sport injury, surgeon, symptom, Syndrome, traumatic brain injury, unconsciousness},
pubstate = {published},
tppubtype = {article}
}
Rabb, C H
Comments Journal Article
In: Neurosurgery, vol. 67, no. 4, pp. 1027–1028, 2010, ISBN: 0148-396X.
BibTeX | Tags: brain concussion, functional magnetic resonance imaging, human, Imaging & EEG, mental task, neuroimaging, Note, priority journal, sport injury, working memory Overviews
@article{Rabb2010,
title = {Comments},
author = {Rabb, C H},
isbn = {0148-396X},
year = {2010},
date = {2010-01-01},
journal = {Neurosurgery},
volume = {67},
number = {4},
pages = {1027--1028},
keywords = {brain concussion, functional magnetic resonance imaging, human, Imaging \& EEG, mental task, neuroimaging, Note, priority journal, sport injury, working memory Overviews},
pubstate = {published},
tppubtype = {article}
}
Pangilinan, P H; Hornyak, J E
Controversial topic: return to competitive sport after severe traumatic brain injury Journal Article
In: Brain Injury, vol. 21, no. 12, pp. 1315–1317, 2007, ISBN: 0269-9052.
Abstract | BibTeX | Tags: Athletes, brain concussion, Brain Injuries -- Rehabilitation, Case Studies, human, Severity of Injury, Sports, Sports Re-Entry
@article{Pangilinan2007,
title = {Controversial topic: return to competitive sport after severe traumatic brain injury},
author = {Pangilinan, P H and Hornyak, J E},
isbn = {0269-9052},
year = {2007},
date = {2007-01-01},
journal = {Brain Injury},
volume = {21},
number = {12},
pages = {1315--1317},
publisher = {Taylor \& Francis Ltd},
address = {Philadelphia, Pennsylvania},
abstract = {Various guidelines have been proposed for returning to sport after concussion or mild TBI. However, no such guidelines exist for severe TBI. This study presents three cases of athletes who sustained severe TBIs and returned to competition. The rational for their clearance will be discussed.},
keywords = {Athletes, brain concussion, Brain Injuries -- Rehabilitation, Case Studies, human, Severity of Injury, Sports, Sports Re-Entry},
pubstate = {published},
tppubtype = {article}
}
Barr, William B
Recovering from mild traumatic brain injury: What psychology has learned from sports concussion research Journal Article
In: NYS Psychologist, vol. 19, no. 5, pp. 24–29, 2007, ISBN: 1048-6925.
Abstract | BibTeX | Tags: 2007, brain concussion, disorder recovery, mild traumatic brain injury, psychology, Recovery (Disorders), Sports, sports concussion, traumatic brain injury
@article{Barr2007,
title = {Recovering from mild traumatic brain injury: What psychology has learned from sports concussion research},
author = {Barr, William B},
isbn = {1048-6925},
year = {2007},
date = {2007-01-01},
journal = {NYS Psychologist},
volume = {19},
number = {5},
pages = {24--29},
publisher = {New York State Psychological Assn},
address = {US},
abstract = {Research on sports concussion has contributed significantly to our knowledge on the characteristics and course of recovery from mild traumatic brain injury (MTBI). Findings from research studies on injured athletes indicate that most symptoms of concussion resolve within 7-10 days of the injury. Results from studies examining the development of more persistent symptoms have found relationships with a number of psychological factors, including expectation and maladaptive coping styles. Systematic reviews of intervention strategies have indicated that psychological approaches to treatment of MTBI, such as early education and support, are more effective than any form of drug treatment. Psychologists should be aware of these findings and the potential for playing a significant role in treating individuals with MTBI. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2007, brain concussion, disorder recovery, mild traumatic brain injury, psychology, Recovery (Disorders), Sports, sports concussion, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Quintana, E C
[Commentary on] Recovery from mild concussion in high school athletes Journal Article
In: Annals of Emergency Medicine, vol. 43, no. 5, pp. 680–681, 2004, ISBN: 0196-0644.
BibTeX | Tags: Athletes, brain concussion, Cognition Disorders -- Etiology, high school, Recovery
@article{Quintana2004,
title = {[Commentary on] Recovery from mild concussion in high school athletes},
author = {Quintana, E C},
isbn = {0196-0644},
year = {2004},
date = {2004-01-01},
journal = {Annals of Emergency Medicine},
volume = {43},
number = {5},
pages = {680--681},
publisher = {Elsevier Science},
address = {New York, New York},
keywords = {Athletes, brain concussion, Cognition Disorders -- Etiology, high school, Recovery},
pubstate = {published},
tppubtype = {article}
}
Bernstein, Daniel M
Information processing difficulty long after self-reported concussion Journal Article
In: Journal of the International Neuropsychological Society, vol. 8, no. 5, pp. 673–682, 2002, ISBN: 1355-6177 1469-7661.
Abstract | Links | BibTeX | Tags: 2002, attention, attention tasks, brain concussion, Cognitive Ability, cognitive tasks, information processing, Mild head injury, self-report concussion
@article{Bernstein2002,
title = {Information processing difficulty long after self-reported concussion},
author = {Bernstein, Daniel M},
doi = {10.1017/S1355617702801400},
isbn = {1355-6177
1469-7661},
year = {2002},
date = {2002-01-01},
journal = {Journal of the International Neuropsychological Society},
volume = {8},
number = {5},
pages = {673--682},
publisher = {Cambridge University Press},
address = {United Kingdom},
abstract = {The present study replicates and extends previous work in which university students with self-reported concussion demonstrated reduced P300 amplitude on a set of easy and difficult attention tasks, in addition to performing more poorly than controls on demanding cognitive tasks many years after injury. In the present study, 13 students with self-reported concussion (MHI group: M time since injury = 8 years) and 10 controls were matched for age, sex, education, and a variety of cognitive, physical and emotional complaints. Controls outperformed the MHI group on the Digit Symbol substitution task and on a difficult dual task involving tone discrimination and visual working memory. Additionally, controls exhibited larger P300 amplitudes on both an easy and a difficult auditory discrimination task. A combination of electrophysiological, neuropsychological and self-report indices predicted group membership (MHI vs. control) with 88% accuracy. The present results, coupled with previous work, offer preliminary evidence that the combination of event-related potentials and demanding behavioral measures might reveal long-lasting, subtle cognitive problems associated with MHI. These findings may challenge existing notions of complete recovery after MHI. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2002, attention, attention tasks, brain concussion, Cognitive Ability, cognitive tasks, information processing, Mild head injury, self-report concussion},
pubstate = {published},
tppubtype = {article}
}