Czerniak, S M; Sikoglu, E M; Liso Navarro, A A; McCafferty, J; Eisenstock, J; Stevenson, J H; King, J A; Moore, C M
A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270] Journal Article
In: Brain Imaging & Behavior, vol. 9, no. 2, pp. 323–332, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Concussion/pp [Physiopathology], *Brain/pp [Physiopathology], Adolescent, Athletes, BRAIN mapping, Female, Humans, interview, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Psychological, rest, Young Adult
@article{Czerniak2015b,
title = {A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270]},
author = {Czerniak, S M and Sikoglu, E M and {Liso Navarro}, A A and McCafferty, J and Eisenstock, J and Stevenson, J H and King, J A and Moore, C M},
year = {2015},
date = {2015-01-01},
journal = {Brain Imaging \& Behavior},
volume = {9},
number = {2},
pages = {323--332},
abstract = {Sports-related concussions are currently diagnosed through multi-domain assessment by a medical professional and may utilize neurocognitive testing as an aid. However, these tests have only been able to detect differences in the days to week post-concussion. Here, we investigate a measure of brain function, namely resting state functional connectivity, which may detect residual brain differences in the weeks to months after concussion. Twenty-one student athletes (9 concussed within 6 months of enrollment; 12 non-concussed; between ages 18 and 22 years) were recruited for this study. All participants completed the Wisconsin Card Sorting Task and the Color-Word Interference Test. Neuroimaging data, specifically resting state functional Magnetic Resonance Imaging data, were acquired to examine resting state functional connectivity. Two sample t-tests were used to compare the neurocognitive scores and resting state functional connectivity patterns among concussed and non-concussed participants. Correlations between neurocognitive scores and resting state functional connectivity measures were also determined across all subjects. There were no significant differences in neurocognitive performance between concussed and non-concussed groups. Concussed subjects had significantly increased connections between areas of the brain that underlie executive function. Across all subjects, better neurocognitive performance corresponded to stronger brain connectivity. Even at rest, brains of concussed athletes may have to 'work harder' than their healthy peers to achieve similar neurocognitive results. Resting state brain connectivity may be able to detect prolonged brain differences in concussed athletes in a more quantitative manner than neurocognitive test scores.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Concussion/pp [Physiopathology], *Brain/pp [Physiopathology], Adolescent, Athletes, BRAIN mapping, Female, Humans, interview, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Psychological, rest, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}
Czerniak, S M; Sikoglu, E M; Liso Navarro, A A; McCafferty, J; Eisenstock, J; Stevenson, J H; King, J A; Moore, C M
A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270] Journal Article
In: Brain Imaging & Behavior, vol. 9, no. 2, pp. 323–332, 2015.
@article{Czerniak2015b,
title = {A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270]},
author = {Czerniak, S M and Sikoglu, E M and {Liso Navarro}, A A and McCafferty, J and Eisenstock, J and Stevenson, J H and King, J A and Moore, C M},
year = {2015},
date = {2015-01-01},
journal = {Brain Imaging \& Behavior},
volume = {9},
number = {2},
pages = {323--332},
abstract = {Sports-related concussions are currently diagnosed through multi-domain assessment by a medical professional and may utilize neurocognitive testing as an aid. However, these tests have only been able to detect differences in the days to week post-concussion. Here, we investigate a measure of brain function, namely resting state functional connectivity, which may detect residual brain differences in the weeks to months after concussion. Twenty-one student athletes (9 concussed within 6 months of enrollment; 12 non-concussed; between ages 18 and 22 years) were recruited for this study. All participants completed the Wisconsin Card Sorting Task and the Color-Word Interference Test. Neuroimaging data, specifically resting state functional Magnetic Resonance Imaging data, were acquired to examine resting state functional connectivity. Two sample t-tests were used to compare the neurocognitive scores and resting state functional connectivity patterns among concussed and non-concussed participants. Correlations between neurocognitive scores and resting state functional connectivity measures were also determined across all subjects. There were no significant differences in neurocognitive performance between concussed and non-concussed groups. Concussed subjects had significantly increased connections between areas of the brain that underlie executive function. Across all subjects, better neurocognitive performance corresponded to stronger brain connectivity. Even at rest, brains of concussed athletes may have to 'work harder' than their healthy peers to achieve similar neurocognitive results. Resting state brain connectivity may be able to detect prolonged brain differences in concussed athletes in a more quantitative manner than neurocognitive test scores.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Czerniak, S M; Sikoglu, E M; Liso Navarro, A A; McCafferty, J; Eisenstock, J; Stevenson, J H; King, J A; Moore, C M
A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270] Journal Article
In: Brain Imaging & Behavior, vol. 9, no. 2, pp. 323–332, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Concussion/pp [Physiopathology], *Brain/pp [Physiopathology], Adolescent, Athletes, BRAIN mapping, Female, Humans, interview, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Psychological, rest, Young Adult
@article{Czerniak2015b,
title = {A resting state functional magnetic resonance imaging study of concussion in collegiate athletes.[Erratum appears in Brain Imaging Behav. 2015 Sep;9(3):650; PMID: 25326270]},
author = {Czerniak, S M and Sikoglu, E M and {Liso Navarro}, A A and McCafferty, J and Eisenstock, J and Stevenson, J H and King, J A and Moore, C M},
year = {2015},
date = {2015-01-01},
journal = {Brain Imaging \& Behavior},
volume = {9},
number = {2},
pages = {323--332},
abstract = {Sports-related concussions are currently diagnosed through multi-domain assessment by a medical professional and may utilize neurocognitive testing as an aid. However, these tests have only been able to detect differences in the days to week post-concussion. Here, we investigate a measure of brain function, namely resting state functional connectivity, which may detect residual brain differences in the weeks to months after concussion. Twenty-one student athletes (9 concussed within 6 months of enrollment; 12 non-concussed; between ages 18 and 22 years) were recruited for this study. All participants completed the Wisconsin Card Sorting Task and the Color-Word Interference Test. Neuroimaging data, specifically resting state functional Magnetic Resonance Imaging data, were acquired to examine resting state functional connectivity. Two sample t-tests were used to compare the neurocognitive scores and resting state functional connectivity patterns among concussed and non-concussed participants. Correlations between neurocognitive scores and resting state functional connectivity measures were also determined across all subjects. There were no significant differences in neurocognitive performance between concussed and non-concussed groups. Concussed subjects had significantly increased connections between areas of the brain that underlie executive function. Across all subjects, better neurocognitive performance corresponded to stronger brain connectivity. Even at rest, brains of concussed athletes may have to 'work harder' than their healthy peers to achieve similar neurocognitive results. Resting state brain connectivity may be able to detect prolonged brain differences in concussed athletes in a more quantitative manner than neurocognitive test scores.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Concussion/pp [Physiopathology], *Brain/pp [Physiopathology], Adolescent, Athletes, BRAIN mapping, Female, Humans, interview, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Psychological, rest, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}