Elder, G A
Update on TBI and Cognitive Impairment in Military Veterans Journal Article
In: Current Neurology & Neuroscience Reports, vol. 15, no. 10, pp. 68, 2015.
Abstract | BibTeX | Tags: *Brain Injuries/pp [Physiopathology], *Cognition Disorders/pp [Physiopathology], *Veterans, Blast Injuries/co [Complications], Blast Injuries/pp [Physiopathology], Brain Injuries/co [Complications], Cognition Disorders/et [Etiology], Humans, Post-Traumatic/pp [Physiopatholo, Risk Factors, Stress Disorders
@article{Elder2015,
title = {Update on TBI and Cognitive Impairment in Military Veterans},
author = {Elder, G A},
year = {2015},
date = {2015-01-01},
journal = {Current Neurology \& Neuroscience Reports},
volume = {15},
number = {10},
pages = {68},
abstract = {Traumatic brain injury (TBI) is a common cause of morbidity and mortality in military life. Interest in military TBI has increased recently due to the conflicts in Iraq and Afghanistan. Certain types of TBI are relatively unique to the military, the most prominent being blast-related TBI. Blast-related mild TBI has been of particular concern in veterans from the most recent conflicts although controversy remains concerning its separation from post-traumatic stress disorder. TBI is also a risk factor for the later development of neurodegenerative diseases in which cognitive impairment is prominent putting veterans at risk for disorders including Alzheimer's disease and chronic traumatic encephalopathy. Recent evidence associating TBI with chronic cognitive impairment is reviewed in the context of its relevance to military veterans.},
keywords = {*Brain Injuries/pp [Physiopathology], *Cognition Disorders/pp [Physiopathology], *Veterans, Blast Injuries/co [Complications], Blast Injuries/pp [Physiopathology], Brain Injuries/co [Complications], Cognition Disorders/et [Etiology], Humans, Post-Traumatic/pp [Physiopatholo, Risk Factors, Stress Disorders},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}
Kiraly, M; Kiraly, S J
Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia Journal Article
In: TheScientificWorldJournal, vol. 7, pp. 1768–1776, 2007.
Abstract | BibTeX | Tags: *Brain Injuries/co [Complications], *Brain Injuries/pp [Physiopathology], *Brain/pp [Physiopathology], *Dementia/et [Etiology], *Dementia/pp [Physiopathology], *Models, Animals, Humans, Neurological
@article{Kiraly2007,
title = {Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia},
author = {Kiraly, M and Kiraly, S J},
year = {2007},
date = {2007-01-01},
journal = {TheScientificWorldJournal},
volume = {7},
pages = {1768--1776},
abstract = {Brain injuries are too common. Most people are unaware of the incidence of and horrendous consequences of traumatic brain injury (TBI) and mild traumatic brain injury (MTBI). Research and the advent of sophisticated imaging have led to progression in the understanding of brain pathophysiology following TBI. Seminal evidence from animal and human experiments demonstrate links between TBI and the subsequent onset of premature, psychiatric syndromes and neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Objectives of this summary are, therefore, to instill appreciation regarding the importance of brain injury prevention, diagnosis, and treatment, and to increase awareness regarding the long-term delayed consequences following TBI. [References: 88]},
keywords = {*Brain Injuries/co [Complications], *Brain Injuries/pp [Physiopathology], *Brain/pp [Physiopathology], *Dementia/et [Etiology], *Dementia/pp [Physiopathology], *Models, Animals, Humans, Neurological},
pubstate = {published},
tppubtype = {article}
}
De Monte, V E; Geffen, G M; May, C R; McFarland, K; Heath, P; Neralic, M
The acute effects of mild traumatic brain injury on finger tapping with and without word repetition Journal Article
In: Journal of Clinical & Experimental Neuropsychology, vol. 27, no. 2, pp. 224–239, 2005.
Abstract | BibTeX | Tags: *Brain Injuries/pp [Physiopathology], *Fingers/pp [Physiopathology], *Psychomotor Performance/ph [Physiology], *Verbal Learning/ph [Physiology], Adolescent, adult, Demography, Discrimination (Psychology)/ph [Physiology], Female, Fingers/ir [Innervation], Glasgow Coma Scale, Hand Deformities/pp [Physiopathology], Humans, Male, Mental Recall/ph [Physiology], middle aged, Neuropsychological Tests/sn [Statistics & Numerica, Sensitivity and Specificity, Sex Factors, Task Performance and Analysis, Word Association Tests/sn [Statistics & Numerical
@article{DeMonte2005,
title = {The acute effects of mild traumatic brain injury on finger tapping with and without word repetition},
author = {{De Monte}, V E and Geffen, G M and May, C R and McFarland, K and Heath, P and Neralic, M},
year = {2005},
date = {2005-01-01},
journal = {Journal of Clinical \& Experimental Neuropsychology},
volume = {27},
number = {2},
pages = {224--239},
abstract = {This study aimed to investigate the acute effects of mild Traumatic Brain Injury (mTBI) on the performance of a finger tapping and word repetition dual task in order to determine working memory impairment in mTBI. Sixty-four (50 male, 14 female) right-handed cases of mTBI and 26 (18 male and 8 female) right-handed cases of orthopaedic injuries were tested within 24 hours of injury. Patients with mTBI completed fewer correct taps in 10 seconds than patients with orthopaedic injuries, and female mTBI cases repeated fewer words. The size of the dual task decrement did not vary between groups. When added to a test battery including the Rapid Screen of Concussion (RSC; Comerford, Geffen, May, Medland \& Geffen, 2002) and the Digit Symbol Substitution Test, finger tapping speed accounted for 1% of between groups variance and did not improve classification rates of male participants. While the addition of tapping rate did not improve the sensitivity and specificity of the RSC and DSST to mTBI in males, univariate analysis of motor performance in females indicated that dual task performance might be diagnostic. An increase in female sample size is warranted. These results confirm the view that there is a generalized slowing of processing ability following mTBI.},
keywords = {*Brain Injuries/pp [Physiopathology], *Fingers/pp [Physiopathology], *Psychomotor Performance/ph [Physiology], *Verbal Learning/ph [Physiology], Adolescent, adult, Demography, Discrimination (Psychology)/ph [Physiology], Female, Fingers/ir [Innervation], Glasgow Coma Scale, Hand Deformities/pp [Physiopathology], Humans, Male, Mental Recall/ph [Physiology], middle aged, Neuropsychological Tests/sn [Statistics \& Numerica, Sensitivity and Specificity, Sex Factors, Task Performance and Analysis, Word Association Tests/sn [Statistics \& Numerical},
pubstate = {published},
tppubtype = {article}
}
Davis, A E
Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations Journal Article
In: Critical Care Nursing Quarterly, vol. 23, no. 3, pp. 1–13, 2000.
Abstract | BibTeX | Tags: *Brain Injuries/pa [Pathology], *Brain Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Injuries/cl [Classification], Brain Injuries/co [Complications], Brain/me [Metabolism], Brain/pa [Pathology], Humans, intracranial hemorrhage, Neurons/me [Metabolism], Neurons/pa [Pathology], Nonpenetrating/pa [Pathology], Nonpenetrating/pp [Physiopathology], Skull Fractures/pa [Pathology], Skull Fractures/pp [Physiopathology], Traumatic/pa [Pathology], Traumatic/pp [Physiopatho, Wounds
@article{Davis2000,
title = {Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations},
author = {Davis, A E},
year = {2000},
date = {2000-01-01},
journal = {Critical Care Nursing Quarterly},
volume = {23},
number = {3},
pages = {1--13},
abstract = {Traumatic brain injury (TBI) is a public health problem of great concern, because it affects more than 2 million individuals each year. TBI occurs as a result of motor vehicle crashes, falls, and sports-related events. Biomechanical mechanisms occurring at the time of the injury initiate primary and secondary injuries that evolve over several days. In this article the relationship between an blunt injury event and the subsequent damage produced is addressed. Mechanisms of brain injury from biomechanics to cellular pathobiology are presented. Primary and secondary injuries are differentiated, and specific focal and diffuse clinical syndromes are described. Cellular mechanisms responsible for injury are also addressed, because they provide the unifying concepts across the many clinical syndromes so often discussed separately in reviews of traumatic brain injury. [References: 26]},
keywords = {*Brain Injuries/pa [Pathology], *Brain Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Injuries/cl [Classification], Brain Injuries/co [Complications], Brain/me [Metabolism], Brain/pa [Pathology], Humans, intracranial hemorrhage, Neurons/me [Metabolism], Neurons/pa [Pathology], Nonpenetrating/pa [Pathology], Nonpenetrating/pp [Physiopathology], Skull Fractures/pa [Pathology], Skull Fractures/pp [Physiopathology], Traumatic/pa [Pathology], Traumatic/pp [Physiopatho, Wounds},
pubstate = {published},
tppubtype = {article}
}
Elder, G A
Update on TBI and Cognitive Impairment in Military Veterans Journal Article
In: Current Neurology & Neuroscience Reports, vol. 15, no. 10, pp. 68, 2015.
@article{Elder2015,
title = {Update on TBI and Cognitive Impairment in Military Veterans},
author = {Elder, G A},
year = {2015},
date = {2015-01-01},
journal = {Current Neurology \& Neuroscience Reports},
volume = {15},
number = {10},
pages = {68},
abstract = {Traumatic brain injury (TBI) is a common cause of morbidity and mortality in military life. Interest in military TBI has increased recently due to the conflicts in Iraq and Afghanistan. Certain types of TBI are relatively unique to the military, the most prominent being blast-related TBI. Blast-related mild TBI has been of particular concern in veterans from the most recent conflicts although controversy remains concerning its separation from post-traumatic stress disorder. TBI is also a risk factor for the later development of neurodegenerative diseases in which cognitive impairment is prominent putting veterans at risk for disorders including Alzheimer's disease and chronic traumatic encephalopathy. Recent evidence associating TBI with chronic cognitive impairment is reviewed in the context of its relevance to military veterans.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Kiraly, M; Kiraly, S J
Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia Journal Article
In: TheScientificWorldJournal, vol. 7, pp. 1768–1776, 2007.
@article{Kiraly2007,
title = {Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia},
author = {Kiraly, M and Kiraly, S J},
year = {2007},
date = {2007-01-01},
journal = {TheScientificWorldJournal},
volume = {7},
pages = {1768--1776},
abstract = {Brain injuries are too common. Most people are unaware of the incidence of and horrendous consequences of traumatic brain injury (TBI) and mild traumatic brain injury (MTBI). Research and the advent of sophisticated imaging have led to progression in the understanding of brain pathophysiology following TBI. Seminal evidence from animal and human experiments demonstrate links between TBI and the subsequent onset of premature, psychiatric syndromes and neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Objectives of this summary are, therefore, to instill appreciation regarding the importance of brain injury prevention, diagnosis, and treatment, and to increase awareness regarding the long-term delayed consequences following TBI. [References: 88]},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
De Monte, V E; Geffen, G M; May, C R; McFarland, K; Heath, P; Neralic, M
The acute effects of mild traumatic brain injury on finger tapping with and without word repetition Journal Article
In: Journal of Clinical & Experimental Neuropsychology, vol. 27, no. 2, pp. 224–239, 2005.
@article{DeMonte2005,
title = {The acute effects of mild traumatic brain injury on finger tapping with and without word repetition},
author = {{De Monte}, V E and Geffen, G M and May, C R and McFarland, K and Heath, P and Neralic, M},
year = {2005},
date = {2005-01-01},
journal = {Journal of Clinical \& Experimental Neuropsychology},
volume = {27},
number = {2},
pages = {224--239},
abstract = {This study aimed to investigate the acute effects of mild Traumatic Brain Injury (mTBI) on the performance of a finger tapping and word repetition dual task in order to determine working memory impairment in mTBI. Sixty-four (50 male, 14 female) right-handed cases of mTBI and 26 (18 male and 8 female) right-handed cases of orthopaedic injuries were tested within 24 hours of injury. Patients with mTBI completed fewer correct taps in 10 seconds than patients with orthopaedic injuries, and female mTBI cases repeated fewer words. The size of the dual task decrement did not vary between groups. When added to a test battery including the Rapid Screen of Concussion (RSC; Comerford, Geffen, May, Medland \& Geffen, 2002) and the Digit Symbol Substitution Test, finger tapping speed accounted for 1% of between groups variance and did not improve classification rates of male participants. While the addition of tapping rate did not improve the sensitivity and specificity of the RSC and DSST to mTBI in males, univariate analysis of motor performance in females indicated that dual task performance might be diagnostic. An increase in female sample size is warranted. These results confirm the view that there is a generalized slowing of processing ability following mTBI.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Davis, A E
Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations Journal Article
In: Critical Care Nursing Quarterly, vol. 23, no. 3, pp. 1–13, 2000.
@article{Davis2000,
title = {Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations},
author = {Davis, A E},
year = {2000},
date = {2000-01-01},
journal = {Critical Care Nursing Quarterly},
volume = {23},
number = {3},
pages = {1--13},
abstract = {Traumatic brain injury (TBI) is a public health problem of great concern, because it affects more than 2 million individuals each year. TBI occurs as a result of motor vehicle crashes, falls, and sports-related events. Biomechanical mechanisms occurring at the time of the injury initiate primary and secondary injuries that evolve over several days. In this article the relationship between an blunt injury event and the subsequent damage produced is addressed. Mechanisms of brain injury from biomechanics to cellular pathobiology are presented. Primary and secondary injuries are differentiated, and specific focal and diffuse clinical syndromes are described. Cellular mechanisms responsible for injury are also addressed, because they provide the unifying concepts across the many clinical syndromes so often discussed separately in reviews of traumatic brain injury. [References: 26]},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Elder, G A
Update on TBI and Cognitive Impairment in Military Veterans Journal Article
In: Current Neurology & Neuroscience Reports, vol. 15, no. 10, pp. 68, 2015.
Abstract | BibTeX | Tags: *Brain Injuries/pp [Physiopathology], *Cognition Disorders/pp [Physiopathology], *Veterans, Blast Injuries/co [Complications], Blast Injuries/pp [Physiopathology], Brain Injuries/co [Complications], Cognition Disorders/et [Etiology], Humans, Post-Traumatic/pp [Physiopatholo, Risk Factors, Stress Disorders
@article{Elder2015,
title = {Update on TBI and Cognitive Impairment in Military Veterans},
author = {Elder, G A},
year = {2015},
date = {2015-01-01},
journal = {Current Neurology \& Neuroscience Reports},
volume = {15},
number = {10},
pages = {68},
abstract = {Traumatic brain injury (TBI) is a common cause of morbidity and mortality in military life. Interest in military TBI has increased recently due to the conflicts in Iraq and Afghanistan. Certain types of TBI are relatively unique to the military, the most prominent being blast-related TBI. Blast-related mild TBI has been of particular concern in veterans from the most recent conflicts although controversy remains concerning its separation from post-traumatic stress disorder. TBI is also a risk factor for the later development of neurodegenerative diseases in which cognitive impairment is prominent putting veterans at risk for disorders including Alzheimer's disease and chronic traumatic encephalopathy. Recent evidence associating TBI with chronic cognitive impairment is reviewed in the context of its relevance to military veterans.},
keywords = {*Brain Injuries/pp [Physiopathology], *Cognition Disorders/pp [Physiopathology], *Veterans, Blast Injuries/co [Complications], Blast Injuries/pp [Physiopathology], Brain Injuries/co [Complications], Cognition Disorders/et [Etiology], Humans, Post-Traumatic/pp [Physiopatholo, Risk Factors, Stress Disorders},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}
Kiraly, M; Kiraly, S J
Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia Journal Article
In: TheScientificWorldJournal, vol. 7, pp. 1768–1776, 2007.
Abstract | BibTeX | Tags: *Brain Injuries/co [Complications], *Brain Injuries/pp [Physiopathology], *Brain/pp [Physiopathology], *Dementia/et [Etiology], *Dementia/pp [Physiopathology], *Models, Animals, Humans, Neurological
@article{Kiraly2007,
title = {Traumatic brain injury and delayed sequelae: a review--traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia},
author = {Kiraly, M and Kiraly, S J},
year = {2007},
date = {2007-01-01},
journal = {TheScientificWorldJournal},
volume = {7},
pages = {1768--1776},
abstract = {Brain injuries are too common. Most people are unaware of the incidence of and horrendous consequences of traumatic brain injury (TBI) and mild traumatic brain injury (MTBI). Research and the advent of sophisticated imaging have led to progression in the understanding of brain pathophysiology following TBI. Seminal evidence from animal and human experiments demonstrate links between TBI and the subsequent onset of premature, psychiatric syndromes and neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Objectives of this summary are, therefore, to instill appreciation regarding the importance of brain injury prevention, diagnosis, and treatment, and to increase awareness regarding the long-term delayed consequences following TBI. [References: 88]},
keywords = {*Brain Injuries/co [Complications], *Brain Injuries/pp [Physiopathology], *Brain/pp [Physiopathology], *Dementia/et [Etiology], *Dementia/pp [Physiopathology], *Models, Animals, Humans, Neurological},
pubstate = {published},
tppubtype = {article}
}
De Monte, V E; Geffen, G M; May, C R; McFarland, K; Heath, P; Neralic, M
The acute effects of mild traumatic brain injury on finger tapping with and without word repetition Journal Article
In: Journal of Clinical & Experimental Neuropsychology, vol. 27, no. 2, pp. 224–239, 2005.
Abstract | BibTeX | Tags: *Brain Injuries/pp [Physiopathology], *Fingers/pp [Physiopathology], *Psychomotor Performance/ph [Physiology], *Verbal Learning/ph [Physiology], Adolescent, adult, Demography, Discrimination (Psychology)/ph [Physiology], Female, Fingers/ir [Innervation], Glasgow Coma Scale, Hand Deformities/pp [Physiopathology], Humans, Male, Mental Recall/ph [Physiology], middle aged, Neuropsychological Tests/sn [Statistics & Numerica, Sensitivity and Specificity, Sex Factors, Task Performance and Analysis, Word Association Tests/sn [Statistics & Numerical
@article{DeMonte2005,
title = {The acute effects of mild traumatic brain injury on finger tapping with and without word repetition},
author = {{De Monte}, V E and Geffen, G M and May, C R and McFarland, K and Heath, P and Neralic, M},
year = {2005},
date = {2005-01-01},
journal = {Journal of Clinical \& Experimental Neuropsychology},
volume = {27},
number = {2},
pages = {224--239},
abstract = {This study aimed to investigate the acute effects of mild Traumatic Brain Injury (mTBI) on the performance of a finger tapping and word repetition dual task in order to determine working memory impairment in mTBI. Sixty-four (50 male, 14 female) right-handed cases of mTBI and 26 (18 male and 8 female) right-handed cases of orthopaedic injuries were tested within 24 hours of injury. Patients with mTBI completed fewer correct taps in 10 seconds than patients with orthopaedic injuries, and female mTBI cases repeated fewer words. The size of the dual task decrement did not vary between groups. When added to a test battery including the Rapid Screen of Concussion (RSC; Comerford, Geffen, May, Medland \& Geffen, 2002) and the Digit Symbol Substitution Test, finger tapping speed accounted for 1% of between groups variance and did not improve classification rates of male participants. While the addition of tapping rate did not improve the sensitivity and specificity of the RSC and DSST to mTBI in males, univariate analysis of motor performance in females indicated that dual task performance might be diagnostic. An increase in female sample size is warranted. These results confirm the view that there is a generalized slowing of processing ability following mTBI.},
keywords = {*Brain Injuries/pp [Physiopathology], *Fingers/pp [Physiopathology], *Psychomotor Performance/ph [Physiology], *Verbal Learning/ph [Physiology], Adolescent, adult, Demography, Discrimination (Psychology)/ph [Physiology], Female, Fingers/ir [Innervation], Glasgow Coma Scale, Hand Deformities/pp [Physiopathology], Humans, Male, Mental Recall/ph [Physiology], middle aged, Neuropsychological Tests/sn [Statistics \& Numerica, Sensitivity and Specificity, Sex Factors, Task Performance and Analysis, Word Association Tests/sn [Statistics \& Numerical},
pubstate = {published},
tppubtype = {article}
}
Davis, A E
Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations Journal Article
In: Critical Care Nursing Quarterly, vol. 23, no. 3, pp. 1–13, 2000.
Abstract | BibTeX | Tags: *Brain Injuries/pa [Pathology], *Brain Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Injuries/cl [Classification], Brain Injuries/co [Complications], Brain/me [Metabolism], Brain/pa [Pathology], Humans, intracranial hemorrhage, Neurons/me [Metabolism], Neurons/pa [Pathology], Nonpenetrating/pa [Pathology], Nonpenetrating/pp [Physiopathology], Skull Fractures/pa [Pathology], Skull Fractures/pp [Physiopathology], Traumatic/pa [Pathology], Traumatic/pp [Physiopatho, Wounds
@article{Davis2000,
title = {Mechanisms of traumatic brain injury: biomechanical, structural and cellular considerations},
author = {Davis, A E},
year = {2000},
date = {2000-01-01},
journal = {Critical Care Nursing Quarterly},
volume = {23},
number = {3},
pages = {1--13},
abstract = {Traumatic brain injury (TBI) is a public health problem of great concern, because it affects more than 2 million individuals each year. TBI occurs as a result of motor vehicle crashes, falls, and sports-related events. Biomechanical mechanisms occurring at the time of the injury initiate primary and secondary injuries that evolve over several days. In this article the relationship between an blunt injury event and the subsequent damage produced is addressed. Mechanisms of brain injury from biomechanics to cellular pathobiology are presented. Primary and secondary injuries are differentiated, and specific focal and diffuse clinical syndromes are described. Cellular mechanisms responsible for injury are also addressed, because they provide the unifying concepts across the many clinical syndromes so often discussed separately in reviews of traumatic brain injury. [References: 26]},
keywords = {*Brain Injuries/pa [Pathology], *Brain Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Injuries/cl [Classification], Brain Injuries/co [Complications], Brain/me [Metabolism], Brain/pa [Pathology], Humans, intracranial hemorrhage, Neurons/me [Metabolism], Neurons/pa [Pathology], Nonpenetrating/pa [Pathology], Nonpenetrating/pp [Physiopathology], Skull Fractures/pa [Pathology], Skull Fractures/pp [Physiopathology], Traumatic/pa [Pathology], Traumatic/pp [Physiopatho, Wounds},
pubstate = {published},
tppubtype = {article}
}