Meehan 3rd, W; Mannix, R; Zafonte, R; Pascual-Leone, A
Chronic traumatic encephalopathy and athletes Journal Article
In: Neurology, vol. 85, no. 17, pp. 1504–1511, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Brain Concussion/pa [Pathology], *Brain Injury, *Brain/pa [Pathology], *Cognition Disorders/pa [Pathology], *Suicidal Ideation, Aggression/px [Psychology], Athletes, Athletic Injuries/co [Complications], Athletic Injuries/px [Psychology], Brain Concussion/co [Complications], Brain Concussion/px [Psychology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Cognition Disorders/et [Etiology], Cognition Disorders/px [Psychology], Headache/et [Etiology], Headache/pa [Pathology], Humans, Mood Disorders/et [Etiology], Mood Disorders/pa [Pathology], Mood Disorders/px [Psychology], Speech Disorders/et [Etiology], Speech Disorders/pa [Pathology], Speech Disorders/px [Psychology]
@article{Meehan3rd2015a,
title = {Chronic traumatic encephalopathy and athletes},
author = {{Meehan 3rd}, W and Mannix, R and Zafonte, R and Pascual-Leone, A},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {17},
pages = {1504--1511},
abstract = {Recent case reports have described athletes previously exposed to repetitive head trauma while participating in contact sports who later in life developed mood disorders, headaches, cognitive difficulties, suicidal ideation, difficulties with speech, and aggressive behavior. Postmortem discoveries show that some of these athletes have pathologic findings that are collectively termed chronic traumatic encephalopathy (CTE). Current hypotheses suggest that concussions or perhaps blows to the head that do not cause the signs and symptoms necessary for making the diagnosis of concussion, so-called subconcussive blows, cause both the clinical and pathologic findings. There are, however, some athletes who participate in contact sports who do not develop the findings ascribed to CTE. Furthermore, there are people who have headaches, mood disorders, cognitive difficulties, suicidal ideation, and other clinical problems who have neither been exposed to repeated head trauma nor possessed the pathologic postmortem findings of those currently diagnosed with CTE. The current lack of prospective data and properly designed case-control studies limits the current understanding of CTE, leading to debate about the causes of the neuropathologic findings and the clinical observations. Given the potential for referral and recall bias in available studies, it remains unclear whether or not the pathologic findings made postmortem cause the presumed neurobehavioral sequela and whether the presumed risk factors, such as sports activity, cerebral concussions, and subconcussive blows, are solely causative of the clinical signs and symptoms. This article discusses the current evidence and the associated limitations. Copyright © 2015 American Academy of Neurology.},
keywords = {*Athletic Injuries/pa [Pathology], *Brain Concussion/pa [Pathology], *Brain Injury, *Brain/pa [Pathology], *Cognition Disorders/pa [Pathology], *Suicidal Ideation, Aggression/px [Psychology], Athletes, Athletic Injuries/co [Complications], Athletic Injuries/px [Psychology], Brain Concussion/co [Complications], Brain Concussion/px [Psychology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Cognition Disorders/et [Etiology], Cognition Disorders/px [Psychology], Headache/et [Etiology], Headache/pa [Pathology], Humans, Mood Disorders/et [Etiology], Mood Disorders/pa [Pathology], Mood Disorders/px [Psychology], Speech Disorders/et [Etiology], Speech Disorders/pa [Pathology], Speech Disorders/px [Psychology]},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Cantu, R C
Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes Journal Article
In: World Neurosurgery, vol. 80, no. 6, pp. 792–793, 2013.
BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Brain/pa [Pathology], *Diffusion Tensor Imaging/mt [Methods], *Neuroimaging/mt [Methods], Humans, Male
@article{Cantu2013,
title = {Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes},
author = {Cantu, R C},
year = {2013},
date = {2013-01-01},
journal = {World Neurosurgery},
volume = {80},
number = {6},
pages = {792--793},
keywords = {*Athletic Injuries/pa [Pathology], *Brain/pa [Pathology], *Diffusion Tensor Imaging/mt [Methods], *Neuroimaging/mt [Methods], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Meehan 3rd, W; Mannix, R; Zafonte, R; Pascual-Leone, A
Chronic traumatic encephalopathy and athletes Journal Article
In: Neurology, vol. 85, no. 17, pp. 1504–1511, 2015.
@article{Meehan3rd2015a,
title = {Chronic traumatic encephalopathy and athletes},
author = {{Meehan 3rd}, W and Mannix, R and Zafonte, R and Pascual-Leone, A},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {17},
pages = {1504--1511},
abstract = {Recent case reports have described athletes previously exposed to repetitive head trauma while participating in contact sports who later in life developed mood disorders, headaches, cognitive difficulties, suicidal ideation, difficulties with speech, and aggressive behavior. Postmortem discoveries show that some of these athletes have pathologic findings that are collectively termed chronic traumatic encephalopathy (CTE). Current hypotheses suggest that concussions or perhaps blows to the head that do not cause the signs and symptoms necessary for making the diagnosis of concussion, so-called subconcussive blows, cause both the clinical and pathologic findings. There are, however, some athletes who participate in contact sports who do not develop the findings ascribed to CTE. Furthermore, there are people who have headaches, mood disorders, cognitive difficulties, suicidal ideation, and other clinical problems who have neither been exposed to repeated head trauma nor possessed the pathologic postmortem findings of those currently diagnosed with CTE. The current lack of prospective data and properly designed case-control studies limits the current understanding of CTE, leading to debate about the causes of the neuropathologic findings and the clinical observations. Given the potential for referral and recall bias in available studies, it remains unclear whether or not the pathologic findings made postmortem cause the presumed neurobehavioral sequela and whether the presumed risk factors, such as sports activity, cerebral concussions, and subconcussive blows, are solely causative of the clinical signs and symptoms. This article discusses the current evidence and the associated limitations. Copyright © 2015 American Academy of Neurology.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Cantu, R C
Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes Journal Article
In: World Neurosurgery, vol. 80, no. 6, pp. 792–793, 2013.
@article{Cantu2013,
title = {Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes},
author = {Cantu, R C},
year = {2013},
date = {2013-01-01},
journal = {World Neurosurgery},
volume = {80},
number = {6},
pages = {792--793},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Meehan 3rd, W; Mannix, R; Zafonte, R; Pascual-Leone, A
Chronic traumatic encephalopathy and athletes Journal Article
In: Neurology, vol. 85, no. 17, pp. 1504–1511, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Brain Concussion/pa [Pathology], *Brain Injury, *Brain/pa [Pathology], *Cognition Disorders/pa [Pathology], *Suicidal Ideation, Aggression/px [Psychology], Athletes, Athletic Injuries/co [Complications], Athletic Injuries/px [Psychology], Brain Concussion/co [Complications], Brain Concussion/px [Psychology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Cognition Disorders/et [Etiology], Cognition Disorders/px [Psychology], Headache/et [Etiology], Headache/pa [Pathology], Humans, Mood Disorders/et [Etiology], Mood Disorders/pa [Pathology], Mood Disorders/px [Psychology], Speech Disorders/et [Etiology], Speech Disorders/pa [Pathology], Speech Disorders/px [Psychology]
@article{Meehan3rd2015a,
title = {Chronic traumatic encephalopathy and athletes},
author = {{Meehan 3rd}, W and Mannix, R and Zafonte, R and Pascual-Leone, A},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {17},
pages = {1504--1511},
abstract = {Recent case reports have described athletes previously exposed to repetitive head trauma while participating in contact sports who later in life developed mood disorders, headaches, cognitive difficulties, suicidal ideation, difficulties with speech, and aggressive behavior. Postmortem discoveries show that some of these athletes have pathologic findings that are collectively termed chronic traumatic encephalopathy (CTE). Current hypotheses suggest that concussions or perhaps blows to the head that do not cause the signs and symptoms necessary for making the diagnosis of concussion, so-called subconcussive blows, cause both the clinical and pathologic findings. There are, however, some athletes who participate in contact sports who do not develop the findings ascribed to CTE. Furthermore, there are people who have headaches, mood disorders, cognitive difficulties, suicidal ideation, and other clinical problems who have neither been exposed to repeated head trauma nor possessed the pathologic postmortem findings of those currently diagnosed with CTE. The current lack of prospective data and properly designed case-control studies limits the current understanding of CTE, leading to debate about the causes of the neuropathologic findings and the clinical observations. Given the potential for referral and recall bias in available studies, it remains unclear whether or not the pathologic findings made postmortem cause the presumed neurobehavioral sequela and whether the presumed risk factors, such as sports activity, cerebral concussions, and subconcussive blows, are solely causative of the clinical signs and symptoms. This article discusses the current evidence and the associated limitations. Copyright © 2015 American Academy of Neurology.},
keywords = {*Athletic Injuries/pa [Pathology], *Brain Concussion/pa [Pathology], *Brain Injury, *Brain/pa [Pathology], *Cognition Disorders/pa [Pathology], *Suicidal Ideation, Aggression/px [Psychology], Athletes, Athletic Injuries/co [Complications], Athletic Injuries/px [Psychology], Brain Concussion/co [Complications], Brain Concussion/px [Psychology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Cognition Disorders/et [Etiology], Cognition Disorders/px [Psychology], Headache/et [Etiology], Headache/pa [Pathology], Humans, Mood Disorders/et [Etiology], Mood Disorders/pa [Pathology], Mood Disorders/px [Psychology], Speech Disorders/et [Etiology], Speech Disorders/pa [Pathology], Speech Disorders/px [Psychology]},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Cantu, R C
Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes Journal Article
In: World Neurosurgery, vol. 80, no. 6, pp. 792–793, 2013.
BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Brain/pa [Pathology], *Diffusion Tensor Imaging/mt [Methods], *Neuroimaging/mt [Methods], Humans, Male
@article{Cantu2013,
title = {Role of diffusion tensor imaging MRI in detecting brain injury in asymptomatic contact athletes},
author = {Cantu, R C},
year = {2013},
date = {2013-01-01},
journal = {World Neurosurgery},
volume = {80},
number = {6},
pages = {792--793},
keywords = {*Athletic Injuries/pa [Pathology], *Brain/pa [Pathology], *Diffusion Tensor Imaging/mt [Methods], *Neuroimaging/mt [Methods], Humans, Male},
pubstate = {published},
tppubtype = {article}
}