Jackson, K; Rubin, R; Van Hoeck, N; Hauert, T; Lana, V; Wang, H
The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers Journal Article
In: Translational Neuroscience, vol. 6, no. 1, pp. 131–138, 2015.
Abstract | Links | BibTeX | Tags: adult, Article, Athletics, body temperature, body temperature measurement, brain, brain temperature, clinical assessment, clinical effectiveness, cognition, cold tolerance, cold treatment, Concussion, diastolic blood pressure, executive function, Feasibility, Female, head neck cooling, Heart Rate, human, human experiment, infrared thermometer, Intervention, Male, mouth temperature, normal human, physiological process, priority journal, pulse oximetry, room temperature, systolic blood pressure, TASK performance, temperature management device, thermoregulation, tympanic temperature, velocity, welkins emt temperature management system, working memory
@article{Jackson2015,
title = {The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers},
author = {Jackson, K and Rubin, R and {Van Hoeck}, N and Hauert, T and Lana, V and Wang, H},
doi = {10.1515/tnsci-2015-0012},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
number = {1},
pages = {131--138},
abstract = {In general, brain temperatures are elevated during physical sporting activities; therefore, reducing brain temperature shortly after a sports-related concussion (SRC) could be a promising intervention technique. The main objective of this study was to examine the effects of head and neck cooling on physiological and cognitive function in normal healthy volunteers. Twelve healthy volunteers underwent two different sessions of combined head and neck cooling, one session with a cold pack and one session with a room temperature pack. Physiological measurements included: systolic/diastolic blood pressure, pulse oximetry, heart rate, and sublingual and tympanic temperature. Cognitive assessment included: processing speed, executive function, and working memory tasks. Physiological measurements were taken pre-, mid- and post-cooling, while cognitive assessments were done before and after cooling. The order of the sessions was randomized. There was a significant decrease in tympanic temperature across both sessions; however more cooling occurred when the cold pack was in the device. There was no significant decrease in sublingual temperature across either session. The observed heart rates, pulse oximetry, systolic and diastolic blood pressure during the sessions were all within range of a normal healthy adult. Cognitive assessment remained stable across each session for both pre- and post-cooling. We propose that optimizing brain temperature management after brain injury using head and neck cooling technology may represent a sensible, practical, and effective strategy to potentially enhance recovery and perhaps minimize the subsequent short and long term consequences from SRC. © 2015 Kevin Jackson et al.},
keywords = {adult, Article, Athletics, body temperature, body temperature measurement, brain, brain temperature, clinical assessment, clinical effectiveness, cognition, cold tolerance, cold treatment, Concussion, diastolic blood pressure, executive function, Feasibility, Female, head neck cooling, Heart Rate, human, human experiment, infrared thermometer, Intervention, Male, mouth temperature, normal human, physiological process, priority journal, pulse oximetry, room temperature, systolic blood pressure, TASK performance, temperature management device, thermoregulation, tympanic temperature, velocity, welkins emt temperature management system, working memory},
pubstate = {published},
tppubtype = {article}
}
Wang, H; Wang, B; Jackson, K; Miller, C M; Hasadsri, L; Llano, D; Rubin, R; Zimmerman, J; Johnson, C; Sutton, B
A novel head-neck cooling device for concussion injury in contact sports Journal Article
In: Translational Neuroscience, vol. 6, pp. 20–31, 2015.
Abstract | Links | BibTeX | Tags: Acceleration, Article, brain concussion, Brain hypothermia, brain perfusion, brain temperature, brain tissue, clinical study, cognition, contact sport, cooling, diving, exercise, exercise induced hyperthermia, experimental study, government, head neck cooling device, Head-neck cooling, human, hyperthermia, induced hypothermia, mild traumatic brain injury, nonhuman, priority journal, randomized controlled trial (topic), sport injury, Sports, surface property, thermal regulating system, thermal stimulation, thermoregulation, traumatic brain injury
@article{Wang2015a,
title = {A novel head-neck cooling device for concussion injury in contact sports},
author = {Wang, H and Wang, B and Jackson, K and Miller, C M and Hasadsri, L and Llano, D and Rubin, R and Zimmerman, J and Johnson, C and Sutton, B},
doi = {10.1515/tnsci-2015-0004},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
pages = {20--31},
abstract = {Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports. © 2015 Huan Wang et al., licensee De Gruyter Open.},
keywords = {Acceleration, Article, brain concussion, Brain hypothermia, brain perfusion, brain temperature, brain tissue, clinical study, cognition, contact sport, cooling, diving, exercise, exercise induced hyperthermia, experimental study, government, head neck cooling device, Head-neck cooling, human, hyperthermia, induced hypothermia, mild traumatic brain injury, nonhuman, priority journal, randomized controlled trial (topic), sport injury, Sports, surface property, thermal regulating system, thermal stimulation, thermoregulation, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Jackson, K; Rubin, R; Van Hoeck, N; Hauert, T; Lana, V; Wang, H
The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers Journal Article
In: Translational Neuroscience, vol. 6, no. 1, pp. 131–138, 2015.
@article{Jackson2015,
title = {The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers},
author = {Jackson, K and Rubin, R and {Van Hoeck}, N and Hauert, T and Lana, V and Wang, H},
doi = {10.1515/tnsci-2015-0012},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
number = {1},
pages = {131--138},
abstract = {In general, brain temperatures are elevated during physical sporting activities; therefore, reducing brain temperature shortly after a sports-related concussion (SRC) could be a promising intervention technique. The main objective of this study was to examine the effects of head and neck cooling on physiological and cognitive function in normal healthy volunteers. Twelve healthy volunteers underwent two different sessions of combined head and neck cooling, one session with a cold pack and one session with a room temperature pack. Physiological measurements included: systolic/diastolic blood pressure, pulse oximetry, heart rate, and sublingual and tympanic temperature. Cognitive assessment included: processing speed, executive function, and working memory tasks. Physiological measurements were taken pre-, mid- and post-cooling, while cognitive assessments were done before and after cooling. The order of the sessions was randomized. There was a significant decrease in tympanic temperature across both sessions; however more cooling occurred when the cold pack was in the device. There was no significant decrease in sublingual temperature across either session. The observed heart rates, pulse oximetry, systolic and diastolic blood pressure during the sessions were all within range of a normal healthy adult. Cognitive assessment remained stable across each session for both pre- and post-cooling. We propose that optimizing brain temperature management after brain injury using head and neck cooling technology may represent a sensible, practical, and effective strategy to potentially enhance recovery and perhaps minimize the subsequent short and long term consequences from SRC. © 2015 Kevin Jackson et al.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Wang, H; Wang, B; Jackson, K; Miller, C M; Hasadsri, L; Llano, D; Rubin, R; Zimmerman, J; Johnson, C; Sutton, B
A novel head-neck cooling device for concussion injury in contact sports Journal Article
In: Translational Neuroscience, vol. 6, pp. 20–31, 2015.
@article{Wang2015a,
title = {A novel head-neck cooling device for concussion injury in contact sports},
author = {Wang, H and Wang, B and Jackson, K and Miller, C M and Hasadsri, L and Llano, D and Rubin, R and Zimmerman, J and Johnson, C and Sutton, B},
doi = {10.1515/tnsci-2015-0004},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
pages = {20--31},
abstract = {Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports. © 2015 Huan Wang et al., licensee De Gruyter Open.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jackson, K; Rubin, R; Van Hoeck, N; Hauert, T; Lana, V; Wang, H
The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers Journal Article
In: Translational Neuroscience, vol. 6, no. 1, pp. 131–138, 2015.
Abstract | Links | BibTeX | Tags: adult, Article, Athletics, body temperature, body temperature measurement, brain, brain temperature, clinical assessment, clinical effectiveness, cognition, cold tolerance, cold treatment, Concussion, diastolic blood pressure, executive function, Feasibility, Female, head neck cooling, Heart Rate, human, human experiment, infrared thermometer, Intervention, Male, mouth temperature, normal human, physiological process, priority journal, pulse oximetry, room temperature, systolic blood pressure, TASK performance, temperature management device, thermoregulation, tympanic temperature, velocity, welkins emt temperature management system, working memory
@article{Jackson2015,
title = {The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers},
author = {Jackson, K and Rubin, R and {Van Hoeck}, N and Hauert, T and Lana, V and Wang, H},
doi = {10.1515/tnsci-2015-0012},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
number = {1},
pages = {131--138},
abstract = {In general, brain temperatures are elevated during physical sporting activities; therefore, reducing brain temperature shortly after a sports-related concussion (SRC) could be a promising intervention technique. The main objective of this study was to examine the effects of head and neck cooling on physiological and cognitive function in normal healthy volunteers. Twelve healthy volunteers underwent two different sessions of combined head and neck cooling, one session with a cold pack and one session with a room temperature pack. Physiological measurements included: systolic/diastolic blood pressure, pulse oximetry, heart rate, and sublingual and tympanic temperature. Cognitive assessment included: processing speed, executive function, and working memory tasks. Physiological measurements were taken pre-, mid- and post-cooling, while cognitive assessments were done before and after cooling. The order of the sessions was randomized. There was a significant decrease in tympanic temperature across both sessions; however more cooling occurred when the cold pack was in the device. There was no significant decrease in sublingual temperature across either session. The observed heart rates, pulse oximetry, systolic and diastolic blood pressure during the sessions were all within range of a normal healthy adult. Cognitive assessment remained stable across each session for both pre- and post-cooling. We propose that optimizing brain temperature management after brain injury using head and neck cooling technology may represent a sensible, practical, and effective strategy to potentially enhance recovery and perhaps minimize the subsequent short and long term consequences from SRC. © 2015 Kevin Jackson et al.},
keywords = {adult, Article, Athletics, body temperature, body temperature measurement, brain, brain temperature, clinical assessment, clinical effectiveness, cognition, cold tolerance, cold treatment, Concussion, diastolic blood pressure, executive function, Feasibility, Female, head neck cooling, Heart Rate, human, human experiment, infrared thermometer, Intervention, Male, mouth temperature, normal human, physiological process, priority journal, pulse oximetry, room temperature, systolic blood pressure, TASK performance, temperature management device, thermoregulation, tympanic temperature, velocity, welkins emt temperature management system, working memory},
pubstate = {published},
tppubtype = {article}
}
Wang, H; Wang, B; Jackson, K; Miller, C M; Hasadsri, L; Llano, D; Rubin, R; Zimmerman, J; Johnson, C; Sutton, B
A novel head-neck cooling device for concussion injury in contact sports Journal Article
In: Translational Neuroscience, vol. 6, pp. 20–31, 2015.
Abstract | Links | BibTeX | Tags: Acceleration, Article, brain concussion, Brain hypothermia, brain perfusion, brain temperature, brain tissue, clinical study, cognition, contact sport, cooling, diving, exercise, exercise induced hyperthermia, experimental study, government, head neck cooling device, Head-neck cooling, human, hyperthermia, induced hypothermia, mild traumatic brain injury, nonhuman, priority journal, randomized controlled trial (topic), sport injury, Sports, surface property, thermal regulating system, thermal stimulation, thermoregulation, traumatic brain injury
@article{Wang2015a,
title = {A novel head-neck cooling device for concussion injury in contact sports},
author = {Wang, H and Wang, B and Jackson, K and Miller, C M and Hasadsri, L and Llano, D and Rubin, R and Zimmerman, J and Johnson, C and Sutton, B},
doi = {10.1515/tnsci-2015-0004},
year = {2015},
date = {2015-01-01},
journal = {Translational Neuroscience},
volume = {6},
pages = {20--31},
abstract = {Emerging research on the long-term impact of concussions on athletes has allowed public recognition of the potentially devastating effects of these and other mild head injuries. Mild traumatic brain injury (mTBI) is a multifaceted disease for which management remains a clinical challenge. Recent pre-clinical and clinical data strongly suggest a destructive synergism between brain temperature elevation and mTBI; conversely, brain hypothermia, with its broader, pleiotropic effects, represents the most potent neuro-protectant in laboratory studies to date. Although well-established in selected clinical conditions, a systemic approach to accomplish regional hypothermia has failed to yield an effective treatment strategy in traumatic brain injury (TBI). Furthermore, although systemic hypothermia remains a potentially valid treatment strategy for moderate to severe TBIs, it is neither practical nor safe for mTBIs. Therefore, selective head-neck cooling may represent an ideal strategy to provide therapeutic benefits to the brain. Optimizing brain temperature management using a National Aeronautics and Space Administration (NASA) spacesuit spinoff head-neck cooling technology before and/or after mTBI in contact sports may represent a sensible, practical, and effective method to potentially enhance recover and minimize post-injury deficits. In this paper, we discuss and summarize the anatomical, physiological, preclinical, and clinical data concerning NASA spinoff head-neck cooling technology as a potential treatment for mTBIs, particularly in the context of contact sports. © 2015 Huan Wang et al., licensee De Gruyter Open.},
keywords = {Acceleration, Article, brain concussion, Brain hypothermia, brain perfusion, brain temperature, brain tissue, clinical study, cognition, contact sport, cooling, diving, exercise, exercise induced hyperthermia, experimental study, government, head neck cooling device, Head-neck cooling, human, hyperthermia, induced hypothermia, mild traumatic brain injury, nonhuman, priority journal, randomized controlled trial (topic), sport injury, Sports, surface property, thermal regulating system, thermal stimulation, thermoregulation, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}