Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
Abstract | Links | BibTeX | Tags: 2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter},
pubstate = {published},
tppubtype = {article}
}
Hwang, Sungjae; Ma, Lei; Kawata, Keisuke; Tierney, Ryan; Jeka, John J
Vestibular dysfunction after subconcussive head impact Journal Article
In: Journal of Neurotrauma, vol. 34, no. 1, pp. 8–15, 2017, ISBN: 0897-7151 1557-9042.
Abstract | Links | BibTeX | Tags: 2017, BEHAVIORAL assessment, Behavioral assessments, Head trauma, Human studies, Outcome measures, Sensory Feedback, sensory function, Soccer, traumatic brain injury
@article{Hwang2017,
title = {Vestibular dysfunction after subconcussive head impact},
author = {Hwang, Sungjae and Ma, Lei and Kawata, Keisuke and Tierney, Ryan and Jeka, John J},
doi = {10.1089/neu.2015.4238},
isbn = {0897-7151
1557-9042},
year = {2017},
date = {2017-01-01},
journal = {Journal of Neurotrauma},
volume = {34},
number = {1},
pages = {8--15},
publisher = {Mary Ann Liebert, Inc.},
address = {US},
abstract = {Current thinking views mild head impact (i.e., subconcussion) as an underrecognized phenomenon that has the ability to cause significant current and future detrimental neurological effects. Repeated mild impacts to the head, however, often display no observable behavioral deficits based on standard clinical tests, which may lack sensitivity. The current study investigates the effects of subconcussive impacts from soccer heading with innovative measures of vestibular function and walking stability in a pre- 0\textendash2 h, post- 24 h post-heading repeated measures design. The heading group (n = 10) executed 10 headers with soccer balls projected at a velocity of 25 mph (11.2 m/sec) over 10 min. Subjects were evaluated 24 h before, immediately after, and 24 h after soccer heading with: the modified Balance Error Scoring System (mBESS); a walking stability task with visual feedback of trunk movement; and galvanic vestibular stimulation (GVS) while standing with eyes closed on foam. A control group (n = 10) followed the same protocol with no heading. The results showed significant decrease in trunk angle, leg angle gain, and center of mass gain relative to GVS for the heading group compared with controls. Medial-lateral trunk orientation displacement and velocity during treadmill walking increased immediately after mild head impact for the heading group compared with controls. Controls showed an improvement in mBESS scores over time, indicating a learning effect, which was not observed with the heading group. These results suggest that mild head impact leads to a transient dysfunction in vestibular processing, which deters walking stability during task performance. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, BEHAVIORAL assessment, Behavioral assessments, Head trauma, Human studies, Outcome measures, Sensory Feedback, sensory function, Soccer, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hwang, Sungjae; Ma, Lei; Kawata, Keisuke; Tierney, Ryan; Jeka, John J
Vestibular dysfunction after subconcussive head impact Journal Article
In: Journal of Neurotrauma, vol. 34, no. 1, pp. 8–15, 2017, ISBN: 0897-7151 1557-9042.
@article{Hwang2017,
title = {Vestibular dysfunction after subconcussive head impact},
author = {Hwang, Sungjae and Ma, Lei and Kawata, Keisuke and Tierney, Ryan and Jeka, John J},
doi = {10.1089/neu.2015.4238},
isbn = {0897-7151
1557-9042},
year = {2017},
date = {2017-01-01},
journal = {Journal of Neurotrauma},
volume = {34},
number = {1},
pages = {8--15},
publisher = {Mary Ann Liebert, Inc.},
address = {US},
abstract = {Current thinking views mild head impact (i.e., subconcussion) as an underrecognized phenomenon that has the ability to cause significant current and future detrimental neurological effects. Repeated mild impacts to the head, however, often display no observable behavioral deficits based on standard clinical tests, which may lack sensitivity. The current study investigates the effects of subconcussive impacts from soccer heading with innovative measures of vestibular function and walking stability in a pre- 0\textendash2 h, post- 24 h post-heading repeated measures design. The heading group (n = 10) executed 10 headers with soccer balls projected at a velocity of 25 mph (11.2 m/sec) over 10 min. Subjects were evaluated 24 h before, immediately after, and 24 h after soccer heading with: the modified Balance Error Scoring System (mBESS); a walking stability task with visual feedback of trunk movement; and galvanic vestibular stimulation (GVS) while standing with eyes closed on foam. A control group (n = 10) followed the same protocol with no heading. The results showed significant decrease in trunk angle, leg angle gain, and center of mass gain relative to GVS for the heading group compared with controls. Medial-lateral trunk orientation displacement and velocity during treadmill walking increased immediately after mild head impact for the heading group compared with controls. Controls showed an improvement in mBESS scores over time, indicating a learning effect, which was not observed with the heading group. These results suggest that mild head impact leads to a transient dysfunction in vestibular processing, which deters walking stability during task performance. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
Abstract | Links | BibTeX | Tags: 2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter},
pubstate = {published},
tppubtype = {article}
}
Hwang, Sungjae; Ma, Lei; Kawata, Keisuke; Tierney, Ryan; Jeka, John J
Vestibular dysfunction after subconcussive head impact Journal Article
In: Journal of Neurotrauma, vol. 34, no. 1, pp. 8–15, 2017, ISBN: 0897-7151 1557-9042.
Abstract | Links | BibTeX | Tags: 2017, BEHAVIORAL assessment, Behavioral assessments, Head trauma, Human studies, Outcome measures, Sensory Feedback, sensory function, Soccer, traumatic brain injury
@article{Hwang2017,
title = {Vestibular dysfunction after subconcussive head impact},
author = {Hwang, Sungjae and Ma, Lei and Kawata, Keisuke and Tierney, Ryan and Jeka, John J},
doi = {10.1089/neu.2015.4238},
isbn = {0897-7151
1557-9042},
year = {2017},
date = {2017-01-01},
journal = {Journal of Neurotrauma},
volume = {34},
number = {1},
pages = {8--15},
publisher = {Mary Ann Liebert, Inc.},
address = {US},
abstract = {Current thinking views mild head impact (i.e., subconcussion) as an underrecognized phenomenon that has the ability to cause significant current and future detrimental neurological effects. Repeated mild impacts to the head, however, often display no observable behavioral deficits based on standard clinical tests, which may lack sensitivity. The current study investigates the effects of subconcussive impacts from soccer heading with innovative measures of vestibular function and walking stability in a pre- 0\textendash2 h, post- 24 h post-heading repeated measures design. The heading group (n = 10) executed 10 headers with soccer balls projected at a velocity of 25 mph (11.2 m/sec) over 10 min. Subjects were evaluated 24 h before, immediately after, and 24 h after soccer heading with: the modified Balance Error Scoring System (mBESS); a walking stability task with visual feedback of trunk movement; and galvanic vestibular stimulation (GVS) while standing with eyes closed on foam. A control group (n = 10) followed the same protocol with no heading. The results showed significant decrease in trunk angle, leg angle gain, and center of mass gain relative to GVS for the heading group compared with controls. Medial-lateral trunk orientation displacement and velocity during treadmill walking increased immediately after mild head impact for the heading group compared with controls. Controls showed an improvement in mBESS scores over time, indicating a learning effect, which was not observed with the heading group. These results suggest that mild head impact leads to a transient dysfunction in vestibular processing, which deters walking stability during task performance. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, BEHAVIORAL assessment, Behavioral assessments, Head trauma, Human studies, Outcome measures, Sensory Feedback, sensory function, Soccer, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}