Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
Abstract | Links | BibTeX | Tags: 2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter},
pubstate = {published},
tppubtype = {article}
}
Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob; Muehlmann, Marc; Weir, Isabelle Ruth; Rauchmann, Boris-Stephan; Shenton, Martha Elizabeth; Koerte, Inga Katharina; Bazarian, Jeffrey John
White matter alterations in college football players: A longitudinal diffusion tensor imaging study Journal Article
In: Brain Imaging & Behavior, 2017, ISBN: 1931-7557.
Abstract | Links | BibTeX | Tags: 2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter
@article{Mayinger2017,
title = {White matter alterations in college football players: A longitudinal diffusion tensor imaging study},
author = {Mayinger, Michael Christian and Merchant-Borna, Kian and Hufschmidt, Jakob and Muehlmann, Marc and Weir, Isabelle Ruth and Rauchmann, Boris-Stephan and Shenton, Martha Elizabeth and Koerte, Inga Katharina and Bazarian, Jeffrey John},
doi = {10.1007/s11682-017-9672-4},
isbn = {1931-7557},
year = {2017},
date = {2017-01-01},
journal = {Brain Imaging \& Behavior},
publisher = {Springer},
address = {Germany},
abstract = {The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non-athlete student controls underwent diffusion MR imaging and computerized cognitive testing at all three timepoints. Whole-brain tract-based spatial statistics (TBSS) were used to compare fractional anisotropy (FA), radial diffusivity (RD), axial diffusivity (AD), and trace between all timepoints. Average diffusion values were obtained from statistically significant clusters for each individual. No athlete suffered a concussion during the study period. After one season of play (T1 to T2), we observed a significant increase in trace in a cluster located in the brainstem and left temporal lobe, and a significant increase in FA in the left parietal lobe. After six months of no-contact rest (T2 to T3), there was a significant decrease in trace and FA in clusters that were partially overlapping or in close proximity with the initial clusters (T1 to T2), with no significant changes from T1 to T3. Repetitive head impacts (RHI) sustained during a single football season may result in alterations of the brain’s WM in collegiate football players. These changes appear to return to baseline after 6 months of no-contact rest, suggesting remission of WM alterations. Our preliminary results suggest that collegiate football players might benefit from periods without exposure to RHI. (PsycINFO Database Record (c) 2017 APA, all rights reserved)},
keywords = {2017, Athletics, Diffusion Tensor Imaging, football, fractional anisotropy, High magnitude impact, Human studies, Longitudinal, No terms assigned, Repetitive head impacts, Sports, Subconcussive head trauma, TBSS, white matter},
pubstate = {published},
tppubtype = {article}
}