Noble, J M
The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later) Journal Article
In: JAMA Neurology, vol. 73, no. 3, pp. 263–265, 2016.
BibTeX | Tags: *Brain Injuries, *Brain Injury, Chronic, football, Humans
@article{Noble2016,
title = {The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later)},
author = {Noble, J M},
year = {2016},
date = {2016-01-01},
journal = {JAMA Neurology},
volume = {73},
number = {3},
pages = {263--265},
keywords = {*Brain Injuries, *Brain Injury, Chronic, football, Humans},
pubstate = {published},
tppubtype = {article}
}
Laksari, K; Wu, L C; Kurt, M; Kuo, C; Camarillo, D C
Resonance of human brain under head acceleration Journal Article
In: Journal of the Royal Society Interface, vol. 12, no. 108, pp. 20150331, 2015.
Abstract | BibTeX | Tags: *Acceleration/ae [Adverse Effects], *BRAIN, *Brain Injuries, *Craniocerebral Trauma, *MAGNETIC resonance imaging, *Skull, adult, Brain Injuries/dg [Diagnostic Imaging], Brain Injuries/pp [Physiopathology], Brain/dg [Diagnostic Imaging], Brain/pp [Physiopathology], Craniocerebral Trauma/dg [Diagnostic Imaging], Craniocerebral Trauma/pp [Physiopathology], Humans, Male, Radiography, Skull/dg [Diagnostic Imaging], Skull/pp [Physiopathology]
@article{Laksari2015,
title = {Resonance of human brain under head acceleration},
author = {Laksari, K and Wu, L C and Kurt, M and Kuo, C and Camarillo, D C},
year = {2015},
date = {2015-01-01},
journal = {Journal of the Royal Society Interface},
volume = {12},
number = {108},
pages = {20150331},
abstract = {Although safety standards have reduced fatal head trauma due to single severe head impacts, mild trauma from repeated head exposures may carry risks of long-term chronic changes in the brain's function and structure. To study the physical sensitivities of the brain to mild head impacts, we developed the first dynamic model of the skull-brain based on in vivo MRI data. We showed that the motion of the brain can be described by a rigid-body with constrained kinematics. We further demonstrated that skull-brain dynamics can be approximated by an under-damped system with a low-frequency resonance at around 15 Hz. Furthermore, from our previous field measurements, we found that head motions in a variety of activities, including contact sports, show a primary frequency of less than 20 Hz. This implies that typical head exposures may drive the brain dangerously close to its mechanical resonance and lead to amplified brain-skull relative motions. Our results suggest a possible cause for mild brain trauma, which could occur due to repetitive low-acceleration head oscillations in a variety of recreational and occupational activities. Copyright © 2015 The Author(s) Published by the Royal Society. All rights reserved.},
keywords = {*Acceleration/ae [Adverse Effects], *BRAIN, *Brain Injuries, *Craniocerebral Trauma, *MAGNETIC resonance imaging, *Skull, adult, Brain Injuries/dg [Diagnostic Imaging], Brain Injuries/pp [Physiopathology], Brain/dg [Diagnostic Imaging], Brain/pp [Physiopathology], Craniocerebral Trauma/dg [Diagnostic Imaging], Craniocerebral Trauma/pp [Physiopathology], Humans, Male, Radiography, Skull/dg [Diagnostic Imaging], Skull/pp [Physiopathology]},
pubstate = {published},
tppubtype = {article}
}
Bartsch, A; Samorezov, S; Benzel, E; Miele, V; Brett, D
Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter Journal Article
In: Stapp Car Crash Journal, vol. 58, pp. 1–27, 2014.
Abstract | BibTeX | Tags: *Acceleration, *Boxing, *Brain Injuries, *Football, *Mouth Protectors, *Telemetry, ALGORITHMS, Biomechanical Phenomena/ph [Physiology], Boxing/in [Injuries], Boxing/ph [Physiology], Brain Injuries/di [Diagnosis], Brain Injuries/et [Etiology], Brain Injuries/pc [Prevention & Control], Brain Injuries/pp [Physiopathology], finite element analysis, Football/in [Injuries], Football/ph [Physiology], Head Protective Devices, Humans, Reproducibility of Results, Telemetry/is [Instrumentation], Telemetry/mt [Methods]
@article{Bartsch2014,
title = {Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter},
author = {Bartsch, A and Samorezov, S and Benzel, E and Miele, V and Brett, D},
year = {2014},
date = {2014-01-01},
journal = {Stapp Car Crash Journal},
volume = {58},
pages = {1--27},
abstract = {Dating to Colonel John Paul Stapp MD in 1975, scientists have desired to measure live human head impacts with accuracy and precision. But no instrument exists to accurately and precisely quantify single head impact events. Our goal is to develop a practical single event head impact dosimeter known as "Intelligent Mouthguard" and quantify its performance on the benchtop, in vitro and in vivo. In the Intelligent Mouthguard hardware, limited gyroscope bandwidth requires an algorithm-based correction as a function of impact duration. After we apply gyroscope correction algorithm, Intelligent Mouthguard results at time of CG linear acceleration peak correlate to the Reference Hybrid III within our tested range of pulse durations and impact acceleration profiles in American football and Boxing in vitro tests: American football},
keywords = {*Acceleration, *Boxing, *Brain Injuries, *Football, *Mouth Protectors, *Telemetry, ALGORITHMS, Biomechanical Phenomena/ph [Physiology], Boxing/in [Injuries], Boxing/ph [Physiology], Brain Injuries/di [Diagnosis], Brain Injuries/et [Etiology], Brain Injuries/pc [Prevention \& Control], Brain Injuries/pp [Physiopathology], finite element analysis, Football/in [Injuries], Football/ph [Physiology], Head Protective Devices, Humans, Reproducibility of Results, Telemetry/is [Instrumentation], Telemetry/mt [Methods]},
pubstate = {published},
tppubtype = {article}
}
Jordan, B D
Neurologic aspects of boxing Journal Article
In: Archives of Neurology, vol. 44, no. 4, pp. 453–459, 1987.
Abstract | BibTeX | Tags: *Athletic Injuries, *Boxing, *Brain Injuries, Athletic Injuries/ep [Epidemiology], Athletic Injuries/pa [Pathology], Athletic Injuries/pc [Prevention & Control], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Injuries/ep [Epidemiology], Brain Injuries/pa [Pathology], Brain Injuries/pc [Prevention & Control], Brain Injuries/pp [Physiopathology], Humans, Magnetic Resonance Spectroscopy, Tomography, X-Ray Computed
@article{Jordan1987,
title = {Neurologic aspects of boxing},
author = {Jordan, B D},
year = {1987},
date = {1987-01-01},
journal = {Archives of Neurology},
volume = {44},
number = {4},
pages = {453--459},
abstract = {The assessment and prevention of potentially adverse neurologic consequences of boxing requires two important considerations. Acute neurologic injuries should be distinguished from chronic brain injuries and the level of competitive boxing (ie, amateur vs professional) must also be taken into account. Acute neurologic injuries such as concussion, post-concussion syndrome, intracranial hemorrhage, and brain contusion are more readily identified than chronic neurologic injuries because of their immediate devastation of the nervous system. In contrast, chronic neurologic injuries differ in their pathophysiologic mechanisms that are exemplified by an insidious onset and progression after the cessation of boxing. Accordingly, the chronic traumatic encephalopathy of boxing poses the most serious neurologic threat of boxing. Amateur boxing differs from professional boxing in the duration of fights, rules and regulatory policies, medical evaluation, and protective devices. These factors could produce a differential effect on the risk of injury to the brain. The prevention of neurologic injuries in boxing requires the integration of proper neurologic evaluation by qualified ring-side physicians, the design and utilization of effective protective devices, and the establishment of national regulatory agencies.},
keywords = {*Athletic Injuries, *Boxing, *Brain Injuries, Athletic Injuries/ep [Epidemiology], Athletic Injuries/pa [Pathology], Athletic Injuries/pc [Prevention \& Control], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Injuries/ep [Epidemiology], Brain Injuries/pa [Pathology], Brain Injuries/pc [Prevention \& Control], Brain Injuries/pp [Physiopathology], Humans, Magnetic Resonance Spectroscopy, Tomography, X-Ray Computed},
pubstate = {published},
tppubtype = {article}
}
Noble, J M
The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later) Journal Article
In: JAMA Neurology, vol. 73, no. 3, pp. 263–265, 2016.
@article{Noble2016,
title = {The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later)},
author = {Noble, J M},
year = {2016},
date = {2016-01-01},
journal = {JAMA Neurology},
volume = {73},
number = {3},
pages = {263--265},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Laksari, K; Wu, L C; Kurt, M; Kuo, C; Camarillo, D C
Resonance of human brain under head acceleration Journal Article
In: Journal of the Royal Society Interface, vol. 12, no. 108, pp. 20150331, 2015.
@article{Laksari2015,
title = {Resonance of human brain under head acceleration},
author = {Laksari, K and Wu, L C and Kurt, M and Kuo, C and Camarillo, D C},
year = {2015},
date = {2015-01-01},
journal = {Journal of the Royal Society Interface},
volume = {12},
number = {108},
pages = {20150331},
abstract = {Although safety standards have reduced fatal head trauma due to single severe head impacts, mild trauma from repeated head exposures may carry risks of long-term chronic changes in the brain's function and structure. To study the physical sensitivities of the brain to mild head impacts, we developed the first dynamic model of the skull-brain based on in vivo MRI data. We showed that the motion of the brain can be described by a rigid-body with constrained kinematics. We further demonstrated that skull-brain dynamics can be approximated by an under-damped system with a low-frequency resonance at around 15 Hz. Furthermore, from our previous field measurements, we found that head motions in a variety of activities, including contact sports, show a primary frequency of less than 20 Hz. This implies that typical head exposures may drive the brain dangerously close to its mechanical resonance and lead to amplified brain-skull relative motions. Our results suggest a possible cause for mild brain trauma, which could occur due to repetitive low-acceleration head oscillations in a variety of recreational and occupational activities. Copyright © 2015 The Author(s) Published by the Royal Society. All rights reserved.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Bartsch, A; Samorezov, S; Benzel, E; Miele, V; Brett, D
Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter Journal Article
In: Stapp Car Crash Journal, vol. 58, pp. 1–27, 2014.
@article{Bartsch2014,
title = {Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter},
author = {Bartsch, A and Samorezov, S and Benzel, E and Miele, V and Brett, D},
year = {2014},
date = {2014-01-01},
journal = {Stapp Car Crash Journal},
volume = {58},
pages = {1--27},
abstract = {Dating to Colonel John Paul Stapp MD in 1975, scientists have desired to measure live human head impacts with accuracy and precision. But no instrument exists to accurately and precisely quantify single head impact events. Our goal is to develop a practical single event head impact dosimeter known as "Intelligent Mouthguard" and quantify its performance on the benchtop, in vitro and in vivo. In the Intelligent Mouthguard hardware, limited gyroscope bandwidth requires an algorithm-based correction as a function of impact duration. After we apply gyroscope correction algorithm, Intelligent Mouthguard results at time of CG linear acceleration peak correlate to the Reference Hybrid III within our tested range of pulse durations and impact acceleration profiles in American football and Boxing in vitro tests: American football},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jordan, B D
Neurologic aspects of boxing Journal Article
In: Archives of Neurology, vol. 44, no. 4, pp. 453–459, 1987.
@article{Jordan1987,
title = {Neurologic aspects of boxing},
author = {Jordan, B D},
year = {1987},
date = {1987-01-01},
journal = {Archives of Neurology},
volume = {44},
number = {4},
pages = {453--459},
abstract = {The assessment and prevention of potentially adverse neurologic consequences of boxing requires two important considerations. Acute neurologic injuries should be distinguished from chronic brain injuries and the level of competitive boxing (ie, amateur vs professional) must also be taken into account. Acute neurologic injuries such as concussion, post-concussion syndrome, intracranial hemorrhage, and brain contusion are more readily identified than chronic neurologic injuries because of their immediate devastation of the nervous system. In contrast, chronic neurologic injuries differ in their pathophysiologic mechanisms that are exemplified by an insidious onset and progression after the cessation of boxing. Accordingly, the chronic traumatic encephalopathy of boxing poses the most serious neurologic threat of boxing. Amateur boxing differs from professional boxing in the duration of fights, rules and regulatory policies, medical evaluation, and protective devices. These factors could produce a differential effect on the risk of injury to the brain. The prevention of neurologic injuries in boxing requires the integration of proper neurologic evaluation by qualified ring-side physicians, the design and utilization of effective protective devices, and the establishment of national regulatory agencies.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Noble, J M
The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later) Journal Article
In: JAMA Neurology, vol. 73, no. 3, pp. 263–265, 2016.
BibTeX | Tags: *Brain Injuries, *Brain Injury, Chronic, football, Humans
@article{Noble2016,
title = {The Long Drive Ahead to Better Understanding Chronic Traumatic Encephalopathy: First (Case) and 10 (Years Later)},
author = {Noble, J M},
year = {2016},
date = {2016-01-01},
journal = {JAMA Neurology},
volume = {73},
number = {3},
pages = {263--265},
keywords = {*Brain Injuries, *Brain Injury, Chronic, football, Humans},
pubstate = {published},
tppubtype = {article}
}
Laksari, K; Wu, L C; Kurt, M; Kuo, C; Camarillo, D C
Resonance of human brain under head acceleration Journal Article
In: Journal of the Royal Society Interface, vol. 12, no. 108, pp. 20150331, 2015.
Abstract | BibTeX | Tags: *Acceleration/ae [Adverse Effects], *BRAIN, *Brain Injuries, *Craniocerebral Trauma, *MAGNETIC resonance imaging, *Skull, adult, Brain Injuries/dg [Diagnostic Imaging], Brain Injuries/pp [Physiopathology], Brain/dg [Diagnostic Imaging], Brain/pp [Physiopathology], Craniocerebral Trauma/dg [Diagnostic Imaging], Craniocerebral Trauma/pp [Physiopathology], Humans, Male, Radiography, Skull/dg [Diagnostic Imaging], Skull/pp [Physiopathology]
@article{Laksari2015,
title = {Resonance of human brain under head acceleration},
author = {Laksari, K and Wu, L C and Kurt, M and Kuo, C and Camarillo, D C},
year = {2015},
date = {2015-01-01},
journal = {Journal of the Royal Society Interface},
volume = {12},
number = {108},
pages = {20150331},
abstract = {Although safety standards have reduced fatal head trauma due to single severe head impacts, mild trauma from repeated head exposures may carry risks of long-term chronic changes in the brain's function and structure. To study the physical sensitivities of the brain to mild head impacts, we developed the first dynamic model of the skull-brain based on in vivo MRI data. We showed that the motion of the brain can be described by a rigid-body with constrained kinematics. We further demonstrated that skull-brain dynamics can be approximated by an under-damped system with a low-frequency resonance at around 15 Hz. Furthermore, from our previous field measurements, we found that head motions in a variety of activities, including contact sports, show a primary frequency of less than 20 Hz. This implies that typical head exposures may drive the brain dangerously close to its mechanical resonance and lead to amplified brain-skull relative motions. Our results suggest a possible cause for mild brain trauma, which could occur due to repetitive low-acceleration head oscillations in a variety of recreational and occupational activities. Copyright © 2015 The Author(s) Published by the Royal Society. All rights reserved.},
keywords = {*Acceleration/ae [Adverse Effects], *BRAIN, *Brain Injuries, *Craniocerebral Trauma, *MAGNETIC resonance imaging, *Skull, adult, Brain Injuries/dg [Diagnostic Imaging], Brain Injuries/pp [Physiopathology], Brain/dg [Diagnostic Imaging], Brain/pp [Physiopathology], Craniocerebral Trauma/dg [Diagnostic Imaging], Craniocerebral Trauma/pp [Physiopathology], Humans, Male, Radiography, Skull/dg [Diagnostic Imaging], Skull/pp [Physiopathology]},
pubstate = {published},
tppubtype = {article}
}
Bartsch, A; Samorezov, S; Benzel, E; Miele, V; Brett, D
Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter Journal Article
In: Stapp Car Crash Journal, vol. 58, pp. 1–27, 2014.
Abstract | BibTeX | Tags: *Acceleration, *Boxing, *Brain Injuries, *Football, *Mouth Protectors, *Telemetry, ALGORITHMS, Biomechanical Phenomena/ph [Physiology], Boxing/in [Injuries], Boxing/ph [Physiology], Brain Injuries/di [Diagnosis], Brain Injuries/et [Etiology], Brain Injuries/pc [Prevention & Control], Brain Injuries/pp [Physiopathology], finite element analysis, Football/in [Injuries], Football/ph [Physiology], Head Protective Devices, Humans, Reproducibility of Results, Telemetry/is [Instrumentation], Telemetry/mt [Methods]
@article{Bartsch2014,
title = {Validation of an "Intelligent Mouthguard" Single Event Head Impact Dosimeter},
author = {Bartsch, A and Samorezov, S and Benzel, E and Miele, V and Brett, D},
year = {2014},
date = {2014-01-01},
journal = {Stapp Car Crash Journal},
volume = {58},
pages = {1--27},
abstract = {Dating to Colonel John Paul Stapp MD in 1975, scientists have desired to measure live human head impacts with accuracy and precision. But no instrument exists to accurately and precisely quantify single head impact events. Our goal is to develop a practical single event head impact dosimeter known as "Intelligent Mouthguard" and quantify its performance on the benchtop, in vitro and in vivo. In the Intelligent Mouthguard hardware, limited gyroscope bandwidth requires an algorithm-based correction as a function of impact duration. After we apply gyroscope correction algorithm, Intelligent Mouthguard results at time of CG linear acceleration peak correlate to the Reference Hybrid III within our tested range of pulse durations and impact acceleration profiles in American football and Boxing in vitro tests: American football},
keywords = {*Acceleration, *Boxing, *Brain Injuries, *Football, *Mouth Protectors, *Telemetry, ALGORITHMS, Biomechanical Phenomena/ph [Physiology], Boxing/in [Injuries], Boxing/ph [Physiology], Brain Injuries/di [Diagnosis], Brain Injuries/et [Etiology], Brain Injuries/pc [Prevention \& Control], Brain Injuries/pp [Physiopathology], finite element analysis, Football/in [Injuries], Football/ph [Physiology], Head Protective Devices, Humans, Reproducibility of Results, Telemetry/is [Instrumentation], Telemetry/mt [Methods]},
pubstate = {published},
tppubtype = {article}
}
Jordan, B D
Neurologic aspects of boxing Journal Article
In: Archives of Neurology, vol. 44, no. 4, pp. 453–459, 1987.
Abstract | BibTeX | Tags: *Athletic Injuries, *Boxing, *Brain Injuries, Athletic Injuries/ep [Epidemiology], Athletic Injuries/pa [Pathology], Athletic Injuries/pc [Prevention & Control], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Injuries/ep [Epidemiology], Brain Injuries/pa [Pathology], Brain Injuries/pc [Prevention & Control], Brain Injuries/pp [Physiopathology], Humans, Magnetic Resonance Spectroscopy, Tomography, X-Ray Computed
@article{Jordan1987,
title = {Neurologic aspects of boxing},
author = {Jordan, B D},
year = {1987},
date = {1987-01-01},
journal = {Archives of Neurology},
volume = {44},
number = {4},
pages = {453--459},
abstract = {The assessment and prevention of potentially adverse neurologic consequences of boxing requires two important considerations. Acute neurologic injuries should be distinguished from chronic brain injuries and the level of competitive boxing (ie, amateur vs professional) must also be taken into account. Acute neurologic injuries such as concussion, post-concussion syndrome, intracranial hemorrhage, and brain contusion are more readily identified than chronic neurologic injuries because of their immediate devastation of the nervous system. In contrast, chronic neurologic injuries differ in their pathophysiologic mechanisms that are exemplified by an insidious onset and progression after the cessation of boxing. Accordingly, the chronic traumatic encephalopathy of boxing poses the most serious neurologic threat of boxing. Amateur boxing differs from professional boxing in the duration of fights, rules and regulatory policies, medical evaluation, and protective devices. These factors could produce a differential effect on the risk of injury to the brain. The prevention of neurologic injuries in boxing requires the integration of proper neurologic evaluation by qualified ring-side physicians, the design and utilization of effective protective devices, and the establishment of national regulatory agencies.},
keywords = {*Athletic Injuries, *Boxing, *Brain Injuries, Athletic Injuries/ep [Epidemiology], Athletic Injuries/pa [Pathology], Athletic Injuries/pc [Prevention \& Control], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Injuries/ep [Epidemiology], Brain Injuries/pa [Pathology], Brain Injuries/pc [Prevention \& Control], Brain Injuries/pp [Physiopathology], Humans, Magnetic Resonance Spectroscopy, Tomography, X-Ray Computed},
pubstate = {published},
tppubtype = {article}
}