Bigler, Erin D; Deibert, Ellen
Lesion analysis in mild traumatic brain injury: Old school goes high tech Journal Article
In: Neurology, vol. 83, no. 14, pp. 1226–1227, 2014, ISBN: 0028-3878 1526-632X.
Abstract | Links | BibTeX | Tags: 2014, ALGORITHMS, brain, functional magnetic resonance imaging, gray matter, mild traumatic brain injury, MRI, traumatic brain injury, white matter
@article{Bigler2014,
title = {Lesion analysis in mild traumatic brain injury: Old school goes high tech},
author = {Bigler, Erin D and Deibert, Ellen},
doi = {10.1212/WNL.0000000000000848},
isbn = {0028-3878
1526-632X},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {14},
pages = {1226--1227},
publisher = {Lippincott Williams \& Wilkins},
address = {US},
abstract = {Comments on an article by Y. W. Lui et al. (see record [rid]2014-43480-004[/rid]). Concussion has been a controversial topic in neurology since the beginning of the discipline. Evidence based diagnostic guidelines have been established,1 but the diagnosis and treatment are largely grounded in clinical decision-making. Clinical and research issues around sports concussion have even reached the levels of government policy with the White House. At the moderate to severe range of traumatic brain injury, neuroimaging provides well-established, objective pathoanatomical biomarkers of the injury. In contrast, conventional neuroimaging findings in mTBI are typically absent. The cognitive and neurobehavioral symptoms of mTBI overlap with any number of neurologic or psychiatric disorders, providing no definitive marker of injury or for tracking injury effects. Reliable biomarkers of mTBI could lead to better clinical decision-making and potential treatments. Deformation-based biomechanical studies of mTBI have shown the thalamus is situated in a particularly vulnerable zone. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2014, ALGORITHMS, brain, functional magnetic resonance imaging, gray matter, mild traumatic brain injury, MRI, traumatic brain injury, white matter},
pubstate = {published},
tppubtype = {article}
}
Kochanek, Patrick M; Bell, Michael J
Making an IMPACT in traumatic brain injury research Journal Article
In: The Lancet Neurology, vol. 12, no. 12, pp. 1132–1133, 2013, ISBN: 1474-4422.
Abstract | Links | BibTeX | Tags: 2013, brain, clinical outcomes, Cognitive Impairment, Magnetic Resonance Imaging, MRI, neurology, Subtypes (Disorders), system dysfunction, topological organization, traumatic brain injury
@article{Kochanek2013,
title = {Making an IMPACT in traumatic brain injury research},
author = {Kochanek, Patrick M and Bell, Michael J},
doi = {10.1016/S1474-4422(13)70245-X},
isbn = {1474-4422},
year = {2013},
date = {2013-01-01},
journal = {The Lancet Neurology},
volume = {12},
number = {12},
pages = {1132--1133},
publisher = {Elsevier Science},
address = {Netherlands},
abstract = {Comments on an article by Maas et al. (see record [rid]2013-40314-020[/rid]). Maas and colleagues review key developments related to 10 years of work by an international group of investigators, the International Mission on Prognosis and Analysis of randomized Controlled Trials in TBI (IMPACT). The investigators identify essential elements for improved clinical trials in TBI, along with a roadmap for future investigations. They suggest that the key elements that have been lacking in clinical trial design for TBI include standardization of data collection (common data elements), accurate quantification of initial prognostic risk, and study designs that appropriately deal with the substantial heterogeneity of the disease. The newly recognised importance of TBI, including the evolution into viewing even mild TBI or concussion as a serious illness rather than regarding it as a so-called badge of honor to be ignored by sports participants, along with the recent major surge in funding of TBI research across the full range of illness by both traditional and new sources, such as the US Army and the National Football League, among others, is leading to a golden age of TBI research with the potential to produce significant breakthroughs. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, brain, clinical outcomes, Cognitive Impairment, Magnetic Resonance Imaging, MRI, neurology, Subtypes (Disorders), system dysfunction, topological organization, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}
Bigler, Erin D; Deibert, Ellen
Lesion analysis in mild traumatic brain injury: Old school goes high tech Journal Article
In: Neurology, vol. 83, no. 14, pp. 1226–1227, 2014, ISBN: 0028-3878 1526-632X.
@article{Bigler2014,
title = {Lesion analysis in mild traumatic brain injury: Old school goes high tech},
author = {Bigler, Erin D and Deibert, Ellen},
doi = {10.1212/WNL.0000000000000848},
isbn = {0028-3878
1526-632X},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {14},
pages = {1226--1227},
publisher = {Lippincott Williams \& Wilkins},
address = {US},
abstract = {Comments on an article by Y. W. Lui et al. (see record [rid]2014-43480-004[/rid]). Concussion has been a controversial topic in neurology since the beginning of the discipline. Evidence based diagnostic guidelines have been established,1 but the diagnosis and treatment are largely grounded in clinical decision-making. Clinical and research issues around sports concussion have even reached the levels of government policy with the White House. At the moderate to severe range of traumatic brain injury, neuroimaging provides well-established, objective pathoanatomical biomarkers of the injury. In contrast, conventional neuroimaging findings in mTBI are typically absent. The cognitive and neurobehavioral symptoms of mTBI overlap with any number of neurologic or psychiatric disorders, providing no definitive marker of injury or for tracking injury effects. Reliable biomarkers of mTBI could lead to better clinical decision-making and potential treatments. Deformation-based biomechanical studies of mTBI have shown the thalamus is situated in a particularly vulnerable zone. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Kochanek, Patrick M; Bell, Michael J
Making an IMPACT in traumatic brain injury research Journal Article
In: The Lancet Neurology, vol. 12, no. 12, pp. 1132–1133, 2013, ISBN: 1474-4422.
@article{Kochanek2013,
title = {Making an IMPACT in traumatic brain injury research},
author = {Kochanek, Patrick M and Bell, Michael J},
doi = {10.1016/S1474-4422(13)70245-X},
isbn = {1474-4422},
year = {2013},
date = {2013-01-01},
journal = {The Lancet Neurology},
volume = {12},
number = {12},
pages = {1132--1133},
publisher = {Elsevier Science},
address = {Netherlands},
abstract = {Comments on an article by Maas et al. (see record [rid]2013-40314-020[/rid]). Maas and colleagues review key developments related to 10 years of work by an international group of investigators, the International Mission on Prognosis and Analysis of randomized Controlled Trials in TBI (IMPACT). The investigators identify essential elements for improved clinical trials in TBI, along with a roadmap for future investigations. They suggest that the key elements that have been lacking in clinical trial design for TBI include standardization of data collection (common data elements), accurate quantification of initial prognostic risk, and study designs that appropriately deal with the substantial heterogeneity of the disease. The newly recognised importance of TBI, including the evolution into viewing even mild TBI or concussion as a serious illness rather than regarding it as a so-called badge of honor to be ignored by sports participants, along with the recent major surge in funding of TBI research across the full range of illness by both traditional and new sources, such as the US Army and the National Football League, among others, is leading to a golden age of TBI research with the potential to produce significant breakthroughs. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Bigler, Erin D; Deibert, Ellen
Lesion analysis in mild traumatic brain injury: Old school goes high tech Journal Article
In: Neurology, vol. 83, no. 14, pp. 1226–1227, 2014, ISBN: 0028-3878 1526-632X.
Abstract | Links | BibTeX | Tags: 2014, ALGORITHMS, brain, functional magnetic resonance imaging, gray matter, mild traumatic brain injury, MRI, traumatic brain injury, white matter
@article{Bigler2014,
title = {Lesion analysis in mild traumatic brain injury: Old school goes high tech},
author = {Bigler, Erin D and Deibert, Ellen},
doi = {10.1212/WNL.0000000000000848},
isbn = {0028-3878
1526-632X},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {14},
pages = {1226--1227},
publisher = {Lippincott Williams \& Wilkins},
address = {US},
abstract = {Comments on an article by Y. W. Lui et al. (see record [rid]2014-43480-004[/rid]). Concussion has been a controversial topic in neurology since the beginning of the discipline. Evidence based diagnostic guidelines have been established,1 but the diagnosis and treatment are largely grounded in clinical decision-making. Clinical and research issues around sports concussion have even reached the levels of government policy with the White House. At the moderate to severe range of traumatic brain injury, neuroimaging provides well-established, objective pathoanatomical biomarkers of the injury. In contrast, conventional neuroimaging findings in mTBI are typically absent. The cognitive and neurobehavioral symptoms of mTBI overlap with any number of neurologic or psychiatric disorders, providing no definitive marker of injury or for tracking injury effects. Reliable biomarkers of mTBI could lead to better clinical decision-making and potential treatments. Deformation-based biomechanical studies of mTBI have shown the thalamus is situated in a particularly vulnerable zone. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2014, ALGORITHMS, brain, functional magnetic resonance imaging, gray matter, mild traumatic brain injury, MRI, traumatic brain injury, white matter},
pubstate = {published},
tppubtype = {article}
}
Kochanek, Patrick M; Bell, Michael J
Making an IMPACT in traumatic brain injury research Journal Article
In: The Lancet Neurology, vol. 12, no. 12, pp. 1132–1133, 2013, ISBN: 1474-4422.
Abstract | Links | BibTeX | Tags: 2013, brain, clinical outcomes, Cognitive Impairment, Magnetic Resonance Imaging, MRI, neurology, Subtypes (Disorders), system dysfunction, topological organization, traumatic brain injury
@article{Kochanek2013,
title = {Making an IMPACT in traumatic brain injury research},
author = {Kochanek, Patrick M and Bell, Michael J},
doi = {10.1016/S1474-4422(13)70245-X},
isbn = {1474-4422},
year = {2013},
date = {2013-01-01},
journal = {The Lancet Neurology},
volume = {12},
number = {12},
pages = {1132--1133},
publisher = {Elsevier Science},
address = {Netherlands},
abstract = {Comments on an article by Maas et al. (see record [rid]2013-40314-020[/rid]). Maas and colleagues review key developments related to 10 years of work by an international group of investigators, the International Mission on Prognosis and Analysis of randomized Controlled Trials in TBI (IMPACT). The investigators identify essential elements for improved clinical trials in TBI, along with a roadmap for future investigations. They suggest that the key elements that have been lacking in clinical trial design for TBI include standardization of data collection (common data elements), accurate quantification of initial prognostic risk, and study designs that appropriately deal with the substantial heterogeneity of the disease. The newly recognised importance of TBI, including the evolution into viewing even mild TBI or concussion as a serious illness rather than regarding it as a so-called badge of honor to be ignored by sports participants, along with the recent major surge in funding of TBI research across the full range of illness by both traditional and new sources, such as the US Army and the National Football League, among others, is leading to a golden age of TBI research with the potential to produce significant breakthroughs. (PsycINFO Database Record (c) 2016 APA, all rights reserved)},
keywords = {2013, brain, clinical outcomes, Cognitive Impairment, Magnetic Resonance Imaging, MRI, neurology, Subtypes (Disorders), system dysfunction, topological organization, traumatic brain injury},
pubstate = {published},
tppubtype = {article}
}